Robust designs for diallel crosses against the missing of one block

Dey & Midha (1996) showed that some of the complete diallel crosses plans, obtained by using triangular partially balanced designs with two associate classes, are optimal. In this investigation, it is derived that these optimal designs for diallel crosses are robust also against the unavailability of one block.     

Complete diallel crosses plans through balanced incomplete block designs

The present investigation involves the methods of construction of complete diallel cross plans using balanced incomplete block (BIB) designs. Furthermore, the analysis of complete diallel crosses plans are carried out to estimate the general combining ability of the ith line (i=1, r 2, r …, r v) where the intra- block analysis of the adjusted sum of squares for GCA and the unadjusted block sum of squares are also obtained, thereafter the relationship between the estimates of BIB design and the estimates of the GCA effect of CDC plan has been established. Moreover, it has also been shown that the complete diallel crosses design obtained through two BIB designs satisfying v1=b1= 4 5 1+3=v2=b2, r r1=2 5 1+1=r2=k1=k2 and 5 1= 5 2 are universally optimum. These results are further supported by a suitable example of each. However, the need of this study is to show that the analysis of the CDC plan is reducible to the analysis of generating the BIB design.     

Application of PBIB designs in CDC Method IV

In this paper we propose the use of some partially balanced incomplete block designs for blocking in complete diallel cross Method IV (Griffing, 1956) to deal with the situation when it is not desirable for all crosses to be accommodated in the block of a traditional randomized block design. A method is also proposed to analyse the MatingEnvironment designs for estimating the general combining ability effect of lines.     

Single replicate orthogonal block designs for circulant partial diallel crosses

Some incomplete block designs for partial diallel crosses have been given in the literature. These designs are obtained by regarding the number of crosses as treatments, and consequently require several replications of each cross. The need for resorting to a partial diallel cross itself implies that it is desired to have fewer crosses. A method for constructing single replicate incomplete block designs for circulant partial diallel crosses is provided in this paper. The designs are orthogonal, and thus they retain full efficiency for estimation of the contrasts of interest.     

Robustness of a complete diallel crosses plan with an unequal number of crosses to the unavailability of one block

The present investigation involved the estimation of the general combining ability of complete diallel crosses (CDC) plans with unequal numbers of crosses, subject to the unavailability of one block for Griffing's system IV . Further, it has been shown that CDC plans with unequal numbers of crosses are fairly robust to the unavailability of one block.     

Robustness of a Class of Partial Diallel Cross Designs to the Unavailability of a Complete Block of Observations

Complete and partial diallel cross designs are examined as to their construction and robustness against the loss of a block of observations. A simple generalized inverse is found for the information matrix of the line effects, which allows evaluation of expressions for the variances of the line-effect differences with and without the missing block. A-efficiencies, based on average variances of the elementary contrasts of the line-effects, suggest that these designs are fairly robust. The loss of efficiency is generally less than 10%, but it is shown that specific comparisons might suffer a loss of efficiency of as much as 40%.     

Optimal row-column designs for complete diallel crosses

Universally optimal row-column designs for complete, diallel crosses are investigated. Three series of designs that require just one replication of the crosses are provided. A series of designs having two replications of each cross is also provided.     

Incomplete block designs for complete diallel crosses and their analysis

A large number of incomplete block designs for Griffing's complete diallel cross-systems I, II and III, involving from five to 12 lines, are suggested, using two-associate triangular partially balanced incomplete block designs. Analysis of incomplete block designs for complete diallel cross-systems has been carried out assuming the most appropriate model for genetic yield, as advocated by Hinklemnann. This includes estimation of the general combining ability, specific combining ability and reciprocal cross- effects. An illustration of the design for each system is presented.     

Optimal block designs for triallel cross experiments

Optimal block designs for a certain type of triallel cross experiments are investigated. Nested balanced block designs are introduced and it is shown how these designs give rise to optimal designs for triallel crosses. Several .series of nested balanced block designs, leading to optimal designs for triallel crosses are reported.     

Search for suitable incomplete block designs for complete diallel cross systems

The suitability of incomplete block designs for each complete diallel cross system I, II, III and IV, under the general genetic model is examined, and a set of necessary conditions obtained. In this connection, modifications in available designs are suggested and illustrated. A table of suitable designs with higher efficiency for complete diallel cross systems is presented.     

Variance-balanced row–column designs involving diallel crosses incorporating specific combining abilities for comparing test lines with a control line

In this paper, the problem of comparing t test lines with a control line under a row–column setup in complete diallel cross experiment is investigated when specific combining ability (sca) effect is included in the model. Three classes of Mating-Environmental Row–Column (MERC) designs have been obtained which are variance balanced for estimating the contrasts pertaining to general combining ability (gca) effects free from sca effects.     

Use of n-ary block designs in diallel crosses evaluation

To fill the gap between theory and practice of modern statistical designs, this paper presents the use of n-ary block designs in the evaluation of balanced incomplete block (BIB) designs for all the four Griffing's (1956) complete dialled crosses (CDC) systems, the construction of which is proposed here by adopting a suitable BIB design and associating its treatments with the crosses under a CDC system.     

A-optimal diallel crosses for test versus control comparisons

A-optimality of block designs for control versus test comparisons in diallel crosses is investigated. A sufficient condition for designs to be A-optimal is derived. Type S₀ designs are defined and A-optimal type S₀ designs are characterized. A lower bound to the A-efficiency of type S₀ designs is also given. Using the lower bound to A-efficiency, type S₀ designs are shown to yield efficient designs for test versus control comparisons.     

The Use of Treatment Concurrences to Assess Robustness of Binary Block Designs Against the Loss of Whole Blocks

Criteria are proposed for assessing the robustness of a binary block design against the loss of whole blocks, based on summing entries of selected upper non‐principal sections of the concurrence matrix. These criteria improve on the minimal concurrence concept that has been used previously and provide new conditions for measuring the robustness status of a design. The robustness properties of two‐associate partially balanced designs are considered and it is shown that two categories of group divisible designs are maximally robust. These results expand a classic result in the literature, obtained by Ghosh, which established maximal robustness for the class of balanced block designs.     

On totally balanced block designs for competition effects

Competition between neighbouring units in field experiments is a serious source of bias. The study of a competing situation needs construction of an environment in which it can happen and the competing units have to appear in a predetermined pattern. This paper describes methods of constructing incomplete block designs balanced for neighbouring competition effects. The designs obtained are totally balanced in the sense that all the effects, direct and neighbours, are estimated with the same variance. The efficiency of these designs has been computed as compared to a complete block design balanced for neighbours and a catalogue has also been prepared.     

Optimal block designs with non additive mixed effects interference

This paper deals with optimality aspects of block designs balanced for interference effects from neighboring units on both sides under a general non additive model along with random block effects. Here, a class of complete, circular block designs strongly balanced for interference effects has been shown to be universally optimal for the estimation of direct effects and interference effects (left and right) of treatments under a non additive mixed effects model.     

Optimal Circular Block Designs for Neighbouring Competition Effects

Competition or interference occurs when the responses to treatments in experimental units are affected by the treatments in neighbouring units. This may contribute to variability in experimental results and lead to substantial losses in efficiency. The study of a competing situation needs designs in which the competing units appear in a predetermined pattern. This paper deals with optimality aspects of circular block designs for studying the competition among treatments applied to neighbouring experimental units. The model considered is a four-way classified model consisting of direct effect of the treatment applied to a particular plot, the effect of those treatments applied to the immediate left and right neighbouring units and the block effect. Conditions have been obtained for the block design to be universally optimal for estimating direct and neighbour effects. Some classes of balanced and strongly balanced complete block designs have been identified to be universally optimal for the estimation of direct, left and right neighbour effects and a list of universally optimal designs for v<20 and r<100 has been prepared.     

On construction of constant block-sum partially balanced incomplete block designs

Abstract

Constant block-sum designs are of interest in repeated measures experimentation where the treatments levels are quantitative and it is desired that at the end of the experiments, all units have been exposed to the same constant cumulative dose. It has been earlier shown that the constant block-sum balanced incomplete block designs do not exist. As the next choice, we, in this article, explore and construct several constant block-sum partially balanced incomplete block designs. A natural choice is to first explore these designs via magic squares and Parshvanath yantram is found to be especially useful in generating designs for block size 4. Using other techniques such as pair-sums and, circular and radial arrangements, we generate a large number of constant block-sum partially balanced incomplete block designs. Their relationship with mixture designs is explored. Finally, we explore the optimization issues when constant block-sum may not be possible for the class of designs with a given set of parameters.     

Robustness group divisible designs

Robustness of group divisible (GD) designs is investigated, when one block is lost, in terms of efficiency of the residual design. The exact evaluation of the efficiency can be made for singular GD and semi-regular GD designs as ell as regular GD designs with λ₁ = 0. In a regular GD design with λ₁ > 0, the efficiency may depend upon the lost block and sharp upper and lower bounds on the efficiency are presented. The investigation shows that GD designs are fairly robust in terms of efficiency. As a special case, we can also show the robustness of balanced incomplete block design when one block is lost.     

Robustness of designed experiments against missing data

This paper investigates the robustness of designed experiments for estimating linear functions of a subset of parameters in a general linear model against the loss of any t( ≥1) observations. Necessary and sufficient conditions for robustness of a design under a homoscedastic model are derived. It is shown that a design robust under a homoscedastic model is also robust under a general heteroscedastic model with correlated observations. As a particular case, necessary and sufficient conditions are obtained for the robustness of block designs against the loss of data. Simple sufficient conditions are also provided for the binary block designs to be robust against the loss of data. Some classes of designs, robust up to three missing observations, are identified. A-efficiency of the residual design is evaluated for certain block designs for several patterns of two missing observations. The efficiency of the residual design has also been worked out when all the observations in any two blocks, not necessarily disjoint, are lost. The lower bound to A-efficiency has also been obtained for the loss of t observations. Finally, a general expression is obtained for the efficiency of the residual design when all the observations of m ( ≥1) disjoint blocks are lost.