An objective Bayesian estimation in a two-period crossover design

Two-period crossover design is one of the commonly used designs in clinical trials. But, the estimation of treatment effect is complicated by the possible presence of carryover effect. It is known that ignoring the carryover effect when it exists can lead to poor estimates of the treatment effect. The classical approach by Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467–480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) consists of two stages. First, a preliminary test is conducted on carryover effect. If the carryover effect is significant, analysis is based only on data from period one; otherwise, analysis is based on data from both periods. A Bayesian approach with improper priors was proposed by Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979–990.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) which uses a mixture of two models: a model with carryover effect and another without. The indeterminacy of the Bayes factor due to the arbitrary constant in the improper prior was addressed by assigning a minimally discriminatory value to the constant. In this article, we present an objective Bayesian estimation approach to the two-period crossover design which is also based on a mixture model, but using the commonly recommended Zellner–Siow g-prior. We provide simulation studies and a real data example and compare the numerical results with Grizzle (1965 Grizzle, J.E. (1965). The two-period change-over design and its use in clinical trials. Biometrics 21:467–480. See Grizzle (1974) for corrections.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar])’s and Grieve (1985 Grieve, A.P. (1985). A Bayesian analysis of the two-period crossover design for clinical trials. Biometrics 41:979–990.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar])’s approaches.     

Bahadur Representation of Linear Kernel Quantile Estimator for Stationary Processes

In this article, we discuss the method of linear kernel quantile estimator proposed by Parzen (1979 Parzen, E. (1979). Nonparametric statistical data modeling. J. Amer. Statist. Assoc. 74:105121.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]). We establish a Bahadur representation in sense of almost surely convergence with the rate log^{? α}n under the case of S-mixing random variable sequence which was proposed by Berkes (2009 Berkes, I., Hörmann, S., (2009). Asymptotic results for the itpirical process of stationary sequences. Stoch. Process. Their Applic. 119:12981324.[Crossref], [Web of Science ®] , [Google Scholar]). We also obtain the strong consistence of this estimator and its convergence rate.     

An extension of almost sure central limit theorem for the maximum of stationary Gaussian random fields

Let X₁, X₂, … be a sequence of stationary standardized Gaussian random fields. The almost sure limit theorem for the maxima of stationary Gaussian random fields is established. Our results extend and improve the results in Csáki and Gonchigdanzan (2002 Csáki, E., Gonchigdanzan, K. (2002). Almost sure limit theorems for the maximum of stationary Gaussian sequences. Stat. Probab. Lett. 58:195–203.[Crossref], [Web of Science ®] , [Google Scholar]) and Choi (2010 Choi, H. (2010). Almost sure limit theorem for stationary Gaussian random fields. J. Korean Stat. Soc. 39:449–454.[Crossref], [Web of Science ®] , [Google Scholar]).     

Buffered Autoregressive Models With Conditional Heteroscedasticity: An Application to Exchange Rates

This article introduces a new model called the buffered autoregressive model with generalized autoregressive conditional heteroscedasticity (BAR-GARCH). The proposed model, as an extension of the BAR model in Li et al. (2015 Li, G.D., Guan, B., Li, W.K., and Yu, P. L.H. (2015), “Hysteretic Autoregressive Time Series Models,” Biometrika, 102, 717–723.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]), can capture the buffering phenomena of time series in both the conditional mean and variance. Thus, it provides us a new way to study the nonlinearity of time series. Compared with the existing AR-GARCH and threshold AR-GARCH models, an application to several exchange rates highlights the importance of the BAR-GARCH model.     

Linear transformation models for survival analysis with tumor growth information in cancer screening study

The complication in analyzing tumor data is that the tumors detected in a screening program tend to be slowly progressive tumors, which is the so-called left-truncated sampling that is inherent in screening studies. Under the assumption that all subjects have the same tumor growth function, Ghosh (2008 Ghosh, D. (2008). Proportional hazards regression for cancer studies. Biometrics 64:141–148.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) developed estimation procedures for the Cox proportional hazards model. Shen (2011a Shen, P.-S. (2011a). Proportional hazards regression for cancer screening data. J. Stat. Comput. Simul. 18:367–377.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) demonstrated that Ghosh (2008 Ghosh, D. (2008). Proportional hazards regression for cancer studies. Biometrics 64:141–148.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar])'s approach can be extended to the case when each subject has a specific growth function. In this article, under linear transformation model, we present a general framework to the analysis of data from cancer screening studies. We developed estimation procedures under linear transformation model, which includes Cox's model as a special case. A simulation study is conducted to demonstrate the potential usefulness of the proposed estimators.     

Bayesian Estimation for Linear Functions of Poisson Rates

The probability matching prior for linear functions of Poisson parameters is derived. A comparison is made between the confidence intervals obtained by Stamey and Hamilton (2006 Stamey, J., Hamilton, C. (2006). A note on confidence intervals for a linear function of Poisson rates. Commun. Statist. Simul. &; Computat. 35(4):849–856.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]), and the intervals derived by us when using the Jeffreys’ and probability matching priors. The intervals obtained from the Jeffreys’ prior are in some cases fiducial intervals (Krishnamoorthy and Lee, 2010 Krishnamoorthy, K., Lee, M. (2010). Inference for functions of parameters in discrete distributions based on fiducial approach: Binomial and Poisson cases. J. Statist. Plann. Infere. 140(5):1182–1192.[Crossref], [Web of Science ®] , [Google Scholar]). A weighted Monte Carlo method is used for the probability matching prior. The power and size of the test, using Bayesian methods, is compared to tests used by Krishnamoorthy and Thomson (2004 Krishnamoorthy, K., Thomson, J. (2004). A more powerful test for comparing two Poisson means. J. Statist. Plann. Infere. 119(1):23–35.[Crossref], [Web of Science ®] , [Google Scholar]). The Jeffreys’, probability matching and two other priors are used.     

Shared inverse Gaussian frailty models based on additive hazards

Frailty models are used in the survival analysis to account for the unobserved heterogeneity in individual risks to disease and death. To analyze the bivariate data on related survival times (e.g., matched pairs experiments, twin, or family data), the shared frailty models were suggested. These models are based on the assumption that frailty acts multiplicatively to hazard rate. In this article, we assume that frailty acts additively to hazard rate. We introduce the shared inverse Gaussian frailty models with three different baseline distributions, namely the generalized log-logistic, the generalized Weibull, and exponential power distribution. We introduce the Bayesian estimation procedure using Markov chain Monte Carlo technique to estimate the parameters involved in these models. We apply these models to a real-life bivariate survival dataset of McGilchrist and Aisbett (1991 McGilchrist, C.A., Aisbett, C.W. (1991). Regression with frailty in survival analysis. Biometrics 47:461–466.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) related to the kidney infection data, and a better model is suggested for the data.     

Minimax estimators for the lower-bounded scale parameter of a location-scale family of distributions

This article is concerned with the minimax estimation of a scale parameter under the quadratic loss function where the family of densities is location-scale type. We obtain results for the case when the scale parameter is bounded below by a known constant. Implications for the estimation of a lower-bounded scale parameter of an exponential distribution are presented under unknown location. Furthermore, classes of improved minimax estimators are derived for the restricted parameter using the Integral Expression for Risk Difference (IERD) approach of Kubokawa (1994 Kubokawa, T. (1994). A unified approach to improving equivariant estimators. Ann. Stat. 22:290–299.[Crossref], [Web of Science ®] , [Google Scholar]). These classes are shown to include some existing estimators from literature.     

A bivariate generalized geometric distribution with applications

This paper proposes a bivariate version of the univariate discrete generalized geometric distribution considered by Gómez–Déniz (2010 Gómez–Déniz, E. (2010). Another generalization of the geometric distribution. Test 19:399–415.[Crossref], [Web of Science ®] , [Google Scholar]). The proposed bivariate distribution can have a positive or negative correlation coefficient which can be used for modeling bivariate-dependent count data. After discussing some of its properties, maximum likelihood estimation is discussed. Two illustrative examples are given for fitting and demonstrating the usefulness of the new bivariate distribution proposed here.     

Fubini theorem for non additive measures in the framework of g-expectation

Since the seminal paper of Ghirardato (1997 Ghirardato, P. 1997. On the independence for non-additive measures, with a Fubini theorem. Journal of Economic Theory 73:261–91.[Crossref], [Web of Science ®] , [Google Scholar]), it is known that Fubini theorem for non additive measures can be available only for functions as “slice-comonotonic” in the framework of product algebra. Later, inspired by Ghirardato (1997 Ghirardato, P. 1997. On the independence for non-additive measures, with a Fubini theorem. Journal of Economic Theory 73:261–91.[Crossref], [Web of Science ®] , [Google Scholar]), Chateauneuf and Lefort (2008 Chateauneuf, A., and J. P. Lefort. 2008. Some Fubini theorems on product σ-algebras for non-additive measures. International Journal of Approximate Reasoning 48:686–96.[Crossref], [Web of Science ®] , [Google Scholar]) obtained some Fubini theorems for non additive measures in the framework of product σ-algebra. In this article, we study Fubini theorem for non additive measures in the framework of g-expectation. We give some different assumptions that provide Fubini theorem in the framework of g-expectation.     

Credibility premium for rate-making systems

Credibility formula has been developed in many fields of actuarial sciences. Based upon Payandeh (2010 Payandeh, A.T. (2010). A new approach to the credibility formula. Insur.: Math. Econ. 46(2):334–338.[Crossref], [Web of Science ®] , [Google Scholar]), this article extends concept of credibility formula to relatively premium of a given rate-making system. More precisely, it calculates Payandeh’s (2010 Payandeh, A.T. (2010). A new approach to the credibility formula. Insur.: Math. Econ. 46(2):334–338.[Crossref], [Web of Science ®] , [Google Scholar]) credibility factor for zero-inflated Poisson gamma distributions with respect to several loss functions. A comparison study has been given.     

Bimodal symmetric-asymmetric power-normal families

This article proposes new symmetric and asymmetric distributions applying methods analogous as the ones in Kim (2005 Kim, H.J. (2005). On a class of two-piece skew-normal distributions. Statist.: J. Theoret. Appl. Statist. 39:537–553.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) and Arnold et al. (2009 Arnold, B.C., H.W. Gómez, and H.S. Salinas. (2009). On multiple constraint skewed models. Statist. J. Theoret. Appl. Statist. 43: 279–293.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) to the exponentiated normal distribution studied in Durrans (1992 Durrans, S.R. (1992). Distributions of fractional order statistics in hydrology. Water Resour. Res. 28:1649–1655.[Crossref], [Web of Science ®] , [Google Scholar]), that we call the power-normal (PN) distribution. The proposed bimodal extension, the main focus of the paper, is called the bimodal power-normal model and is denoted by BPN(α) model, where α is the asymmetry parameter. The authors give some properties including moments and maximum likelihood estimation. Two important features of the model proposed is that its normalizing constant has closed and simple form and that the Fisher information matrix is nonsingular, guaranteeing large sample properties of the maximum likelihood estimators. Finally, simulation studies and real applications reveal that the proposed model can perform well in both situations.     

Frailty models power variance function with cure fraction and latent risk factors negative binomial

In this article, we propose a flexible cure rate model, which is an extension of Cancho et al. (2011 Cancho, V.G., Rodrigues, J., de Castro, M. (2011). A flexible model for survival data with a cure rate: A Bayesian approach. J. Appl. Stat. 38:57–70.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) model, by incorporating a power variance function (PVF) frailty term in latent risk. The model is more flexible in terms of dispersion and it also quantifies the unobservable heterogeneity. The parameter estimation is reached by maximum likelihood estimation procedure and Monte Carlo simulation studies are considered to evaluate the proposed model performance. The practical relevance of the model is illustrated in a real data set of preventing cancer recurrence.     

Efficient Mixture Design Fitting Quadratic Surface with Quantile Responses Using First-degree Polynomial

This study considers efficient mixture designs for the approximation of the response surface of a quantile regression model, which is a second degree polynomial, by a first degree polynomial in the proportions of q components. Instead of least squares estimation in the traditional regression analysis, the objective function in quantile regression models is a weighted sum of absolute deviations and the least absolute deviations (LAD) estimation technique should be used (Bassett and Koenker, 1982 Bassett, G., Koenker, R. (1982). An empirical quantile function for linear models with i.i.d. errors. Journal of the American Statistical Association 77:407–415.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]; Koenker and Bassett, 1978 Koenker, R., Bassett, G. (1978). Regression quantiles. Econometrica 46(1):33–50.[Crossref], [Web of Science ®] , [Google Scholar]). Therefore, the standard optimal mixture designs like the D-optimal or A-optimal mixture designs for the least squared estimation are not appropriate. This study explores mixture designs that minimize the bias between the approximated 1st-degree polynomial and a 2nd-degree polynomial response surfaces by the LAD estimation. In contrast to the standard optimal mixture designs for the least squared estimation, the efficient designs might contain elementary centroid design points of degrees higher than two. An example of a portfolio with five assets is given to illustrate the proposed efficient mixture designs in determining the marginal contribution of risks by individual assets in the portfolio.     

Improved Asymptotics of a Decreasing Mean Residual Life Estimator

The mean residual life of a life distribution, X, with a finite mean is defined by M(t) = E[X ? t|X > t] for t ? 0. Kochar et al. (2000 Kochar, S.C., Mukerjee, H., Samaniego, F.J. (2000). Estimation of a monotone mean residual life. Ann. Stat. 28: 905–921.[Crossref], [Web of Science ®] , [Google Scholar]) provided an estimator of M when it is assumed to be decreasing. They showed that its asymptotic distribution was the same as that of the empirical estimate, but only under very stringent analytic and distributional assumptions. We provide a more general asymptotic theory, and under much weaker conditions. We also provide improved asymptotic confidence bands.     

On the optimal allocation of active redundancies in series system

This paper studies the allocations of two non identical active redundancies in series systems in terms of the reversed hazard rate order and hazard rate order, which generalizes some results built in Valdés and Zequeira (2003 Valdés, J. E., and R. I. Zequeira 2003. On the optimal allocation of an active redundancy in a two-component series system. Stat. Probab. Lett. 63:325–32.[Crossref], [Web of Science ®] , [Google Scholar], 2006 Valdés, J. E., and R. I. Zequeira 2006. On the optimal allocation of two active redundancies in a two-component series system. Oper. Res. Lett. 34:49–52.[Crossref], [Web of Science ®] , [Google Scholar]).     

A new efficient unrelated randomized response model

The present paper suggests an interesting and useful ramification of the unrelated randomized response model due to Pal and Singh (2012 Pal, S., and S. Singh. 2012. A new unrelated question randomized response model. Statistics 46 (1):99–109.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) [A new unrelated question randomized response model. Statistics 46 (1), 99–109] that can be used for any sampling scheme. We have shown theoretically and numerically that the proposed model is more efficient than Pal and Singh (2012 Pal, S., and S. Singh. 2012. A new unrelated question randomized response model. Statistics 46 (1):99–109.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) model.     

Performance of some ridge regression estimators for the multinomial logit model

This article considers several estimators for estimating the ridge parameter k for multinomial logit model based on the work of Khalaf and Shukur (2005 Khalaf, G., and G. Shukur. 2005. Choosing ridge parameters for regression problems. Commun. Statist. Theor. Meth., 34:1177–1182.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]), Alkhamisi et al. (2006 Alkhamisi, M., G. Khalaf, and G. Shukur. 2006. Some modifications for choosing ridge parameters. Commun. Statist. Theor. Meth. 35:2005–2020.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]), and Muniz et al. (2012 Muniz, G., B. M. G. Kibria, K. Månsson, and G. Shukur. 2012. On developing ridge regression parameters: A graphical investigation. in SORT. 36: 115–138.[Web of Science ®] , [Google Scholar]). The mean square error (MSE) is considered as the performance criterion. A simulation study has been conducted to compare the performance of the estimators. Based on the simulation study we found that increasing the correlation between the independent variables and the number of regressors has negative effect on the MSE. However, when the sample size increases the MSE decreases even when the correlation between the independent variables is large. Based on the minimum MSE criterion some useful estimators for estimating the ridge parameter k are recommended for the practitioners.     

On weighted cumulative residual entropy

In analogy with the weighted Shannon entropy proposed by Belis and Guiasu (1968 Belis, M., Guiasu, S. (1968). A quantitative-qualitative measure of information in cybernetic systems. IEEE Trans. Inf. Th. IT-4:593–594.[Crossref], [Web of Science ®] , [Google Scholar]) and Guiasu (1986 Guiasu, S. (1986). Grouping data by using the weighted entropy. J. Stat. Plann. Inference 15:63–69.[Crossref], [Web of Science ®] , [Google Scholar]), we introduce a new information measure called weighted cumulative residual entropy (WCRE). This is based on the cumulative residual entropy (CRE), which is introduced by Rao et al. (2004 Rao, M., Chen, Y., Vemuri, B.C., Wang, F. (2004). Cumulative residual entropy: a new measure of information. IEEE Trans. Info. Theory 50(6):1220–1228.[Crossref], [Web of Science ®] , [Google Scholar]). This new information measure is “length-biased” shift dependent that assigns larger weights to larger values of random variable. The properties of WCRE and a formula relating WCRE and weighted Shannon entropy are given. Related studies of reliability theory is covered. Our results include inequalities and various bounds to the WCRE. Conditional WCRE and some of its properties are discussed. The empirical WCRE is proposed to estimate this new information measure. Finally, strong consistency and central limit theorem are provided.     

Improved Exponential Type Estimators of the Mean of a Sensitive Variable in the Presence of Nonsensitive Auxiliary Information

Recently, Koyuncu et al. (2013 Koyuncu, N., Gupta, S., Sousa, R. (2014). Exponential type estimators of the mean of a sensitive variable in the presence of non-sensitive auxiliary information. Communications in Statistics- Simulation and Computation[PubMed], [Web of Science ®] , [Google Scholar]) proposed an exponential type estimator to improve the efficiency of mean estimator based on randomized response technique. In this article, we propose an improved exponential type estimator which is more efficient than the Koyuncu et al. (2013 Koyuncu, N., Gupta, S., Sousa, R. (2014). Exponential type estimators of the mean of a sensitive variable in the presence of non-sensitive auxiliary information. Communications in Statistics- Simulation and Computation[PubMed], [Web of Science ®] , [Google Scholar]) estimator, which in turn was shown to be more efficient than the usual mean estimator, ratio estimator, regression estimator, and the Gupta et al. (2012 Gupta, S., Shabbir, J., Sousa, R., Corte-Real, P. (2012). Regression estimation of the mean of a sensitive variable in the presence of auxiliary information. Communications in Statistics – Theory and Methods 41:2394–2404.[Taylor &; Francis Online], [Web of Science ®] , [Google Scholar]) estimator. Under simple random sampling without replacement (SRSWOR) scheme, bias and mean square error expressions for the proposed estimator are obtained up to first order of approximation and comparisons are made with the Koyuncu et al. (2013 Koyuncu, N., Gupta, S., Sousa, R. (2014). Exponential type estimators of the mean of a sensitive variable in the presence of non-sensitive auxiliary information. Communications in Statistics- Simulation and Computation[PubMed], [Web of Science ®] , [Google Scholar]) estimator. A simulation study is used to observe the performances of these two estimators. Theoretical findings are also supported by a numerical example with real data. We also show how to, extend the proposed estimator to the case when more than one auxiliary variable is available.