Asymptotic test statistics for coefficients of variation

A one-sample asymptotically normal test statistic Is derived for testing the hypothesis that the coefficient of variation of a normal population is equal to a specified value. Based on this derivation, an asymptotically noraml two-sample test statistic and an asymptotically chi-square k-sample test statistic are derived for testing the hypothesis that the coefficients of variation of k ≥2 normal populations are equal. The two and k-sample test statistics allow for unequal sample sizes. Results of a simulation study which evaluate the size and power of the test statistics and compare the test statistics to earlier ones developed by McKay (1932) and Bennett (1976) are presented.     

Nonparametric Tests for Comparing Several Coefficients of Variation

We consider the problem of comparing (k + 1) coefficients of variation. We are interested in testing the null hypothesis that the coefficients of variation are equal against each of the alternatives: (a) some populations have different coefficients of variation and (b) the coefficients of variation are ordered. Three nonparametric test statistics are proposed and their asymptotic theory is developed. We compared the proposed tests together with another parametric test using two Monte Carlo studies to estimate their probabilities of Type I error and powers. An illustration of the proposed tests using a real data set is given.     

Tests for Coefficients in High‐dimensional Additive Hazard Models

We consider hypothesis testing problems for low‐dimensional coefficients in a high dimensional additive hazard model. A variance reduced partial profiling estimator (VRPPE) is proposed and its asymptotic normality is established, which enables us to test the significance of each single coefficient when the data dimension is much larger than the sample size. Based on the p‐values obtained from the proposed test statistics, we then apply a multiple testing procedure to identify significant coefficients and show that the false discovery rate can be controlled at the desired level. The proposed method is also extended to testing a low‐dimensional sub‐vector of coefficients. The finite sample performance of the proposed testing procedure is evaluated by simulation studies. We also apply it to two real data sets, with one focusing on testing low‐dimensional coefficients and the other focusing on identifying significant coefficients through the proposed multiple testing procedure.     

Asymptotic inference for coefficients of variation

Asymptotic inference results for the coefficients of variation of normal populations are presented in this article. This includes formulas for test statistics, power, confidence intervals, and simultaneous inference. The results are based on the asymptotic normality of the sample coefficient of variation as derived by Miller (1991). An example which compares the homogeneity of bone test samples produced from two different methods is presented.     

Omnibus test of normality using the Q statistic

A new statistical procedure for testing normality is proposed. The Q statistic is derived as the ratio of two linear combinations of the ordered random observations. The coefficients of the linear combinations are utilizing the expected values of the order statistics from the standard normal distribution. This test is omnibus to detect the deviations from normality that result from either skewness or kurtosis. The statistic is independent of the origin and the scale under the null hypothesis of normality, and the null distribution of Q can be very well approximated by the Cornish-Fisher expansion. The powers for various alternative distributions were compared with several other test statistics by simulations.     

Tests on the Equality of Two Multiple Correlation Coefficients

Asymptotic tests are suggested for testing the equality of two multiple correlation coefficients calculated from a single sample from a multivariate normal distribution. An F test is possible only when the two dependent variables coincide and one set of independent variables is a subset of the second set. Tests are compared by simulation for situations in which the F test is inapplicable. Special attention is paid to cases in which asymptotic normality of the test statistics does not hold.     

On Symmetrizing Transformation of the Sample Coefficient of Variation from a Normal Population

Variance-stabilizing transformation (VST) for the sample coefficient of variation is often used as a normalizing transformation and may be used for inference on the population coefficient of variation. However, for small samples, the VST may not be symmetric and hence there is a scope of improvement in its performance by seeking a symmetrizing transformation. This article investigates such a transformation that has been obtained by solving a differential equation. The solution may be complex; hence, a numerical strategy is employed in order to make the approximation practically useful. This transformation has been compared with explicitly available VST. The approach has been illustrated on real data from an agricultural experiment concentrating on inference on single samples; however, the method may be generally applicable to multiple samples when testing the homogeneity of coefficients of variation for many populations by following usual normal-theory-based methods applied on transformed statistics.     

Rényi statistics for testing equality of autocorrelation coefficients

The problem of testing for equality of autocorrelation coefficients of two populations in multivariate data when errors are autocorrelated is considered. We derive Rényi statistics defined as divergences between unrestricted and restricted estimated joint probability density functions and we show that they are asymptotically chi-square distributed under the null hypothesis of interest. Monte Carlo simulation experiments are carried out to investigate the behavior of Rényi statistics and to make comparisons with test statistics based on the approach of Bhandary [M. Bhandary, Test for equality of autocorrelation coefficients for two populations in multivariate data when the errors are autocorrelated, Statistics & Probability Letters 73 (2005) 333–342] for the problem under consideration. Rényi statistics showed to have significantly better behavior.     

Behrens-fisher problem under the assumption of homogeneous coefficients of variation

The powers of the likelihood ratio (LR) test and an “asymptotically (in some sense) optimum” invariant test are examined and compared by simulation techniques with those of several other relevant tests for the problem of testing the equality of two univariate normal population means under the assumption of heterogeneous variances but homogeneous coefficients of variation. It is seen that the LR test is highly satisfactory for all values of the coefficient of variation and the “asymptotically optimum” invariant test, which is computationally much simpler than the LR test, is a reasonably good competitor for cases where the value of the coefficient of variation is greater than or equal to 3. Also, a     

Testing order restricted hypotheses with proportional hazards

Inferences for survival curves based on right censored continuous or grouped data are studied. Testing homogeneity with an ordered restricted alternative and testing the order restriction as the null hypothesis are considered. Under a proportional hazards model, the ordering on the survival curves corresponds to an ordering on the regression coefficients. Approximate likelihood methods are obtained by applying order restricted procedures to the estimates of the regression coefficients. Ordered analogues to the log rank test which are based on the score statistics are considered also. Chi-bar-squared distributions, which have been studied extensively, are shown to provide reasonable approximations to the null distributions of these tests statistics. Using Monte Carlo techniques, the powers of these two types of tests are compared with those that are available in the literature.     

CASE-DELETION DIAGNOSTICS FOR TEST STATISTICS IN MULTIVARIATE REGRESSION

Influence measures in multivariate regression analysis have been widely developed, especially through use of the case-deletion approach. However, there seem to be few accounts of the influence of observations on test statistics in hypothesis testing. This paper examines four common multivariate tests, namely the Wilks' ratio, Lawley-Hotelling trace, Pillai's trace and Roy's greatest root for testing a general linear hypothesis of the regression coefficients in multivariate regression. The influence of observations is measured using the case-deletion approach. The proposed diagnostic measures, except that of Roy's greatest root, can be expressed in terms of statistics without involving the actual deletion of observations. An illustrative example is given with satisfactory results.     

Goodness-of-fit tests for one-shot device accelerated life testing data

In this article, we develop a formal goodness-of-fit testing procedure for one-shot device testing data, in which each observation in the sample is either left censored or right censored. Such data are also called current status data. We provide an algorithm for calculating the nonparametric maximum likelihood estimate (NPMLE) of the unknown lifetime distribution based on such data. Then, we consider four different test statistics that can be used for testing the goodness-of-fit of accelerated failure time (AFT) model by the use of samples of residuals: a chi-square-type statistic based on the difference between the empirical and expected numbers of failures at each inspection time; two other statistics based on the difference between the NPMLE of the lifetime distribution obtained from one-shot device testing data and the distribution specified under the null hypothesis; as a final statistic, we use White's idea of comparing two estimators of the Fisher Information (FI) to propose a test statistic. We then compare these tests in terms of power, and draw some conclusions. Finally, we present an example to illustrate the proposed tests.     

The union-intersection principle applied to the test of dimensionality

In the first section Anderson-Rao-Fujikoshi's test statistics for testing the hypothesis of dimensionality are reviewed and then Olkin-Tomsky's generalized union-intersection principle is applied to show that a new class of test statistics for testing the hypothesis of dimensionality are derived which includes the likelihood ratio test statistics, the trace test statistics and a version of ROY'S maximum root test statistics.     

Preliminary phi-divergence test estimators for linear restrictions in a logistic regression model

The problem of estimation of the parameters in a logistic regression model is considered under multicollinearity situation when it is suspected that the parameter of the logistic regression model may be restricted to a subspace. We study the properties of the preliminary test based on the minimum ϕ -divergence estimator as well as in the ϕ -divergence test statistic. The minimum ϕ -divergence estimator is a natural extension of the maximum likelihood estimator and the ϕ -divergence test statistics is a family of the test statistics for testing the hypothesis that the regression coefficients may be restricted to a subspace.     

Maximizing a Family of Optimal Statistics over a Nuisance Parameter with Applications to Genetic Data Analysis

In this article, a simple algorithm is used to maximize a family of optimal statistics for hypothesis testing with a nuisance parameter not defined under the null hypothesis. This arises from genetic linkage and association studies and other hypothesis testing problems. The maximum of optimal statistics over the nuisance parameter space can be used as a robust test in this situation. Here, we use the maximum and minimum statistics to examine the sensitivity of testing results with respect to the unknown nuisance parameter. Examples from genetic linkage analysis using affected sub pairs and a candidate-gene association study in case-parents trio design are studied.     

Statistical analysis of non-inferiority via non-zero risk difference in stratified matched-pair studies

A stratified study is often designed for adjusting several independent trials in modern medical research. We consider the problem of non-inferiority tests and sample size determinations for a nonzero risk difference in stratified matched-pair studies, and develop the likelihood ratio and Wald-type weighted statistics for testing a null hypothesis of non-zero risk difference for each stratum in stratified matched-pair studies on the basis of (1) the sample-based method and (2) the constrained maximum likelihood estimation (CMLE) method. Sample size formulae for the above proposed statistics are derived, and several choices of weights for Wald-type weighted statistics are considered. We evaluate the performance of the proposed tests according to type I error rates and empirical powers via simulation studies. Empirical results show that (1) the likelihood ratio and the Wald-type CMLE test based on harmonic means of the stratum-specific sample size (SSIZE) weight (the Cochran's test) behave satisfactorily in the sense that their significance levels are much closer to the prespecified nominal level; (2) the likelihood ratio test is better than Nam's [2006. Non-inferiority of new procedure to standard procedure in stratified matched-pair design. Biometrical J. 48, 966–977] score test; (3) the sample sizes obtained by using SSIZE weight are smaller than other weighted statistics in general; (4) the Cochran's test statistic is generally much better than other weighted statistics with CMLE method. A real example from a clinical laboratory study is used to illustrate the proposed methodologies.     

Wald,LM and LR test statistics of linear hypothese in a strutural equation model

For the linear hypothesis in a strucural equation model, the properties of test statistics based on the two stage least squares estimator (2SLSE) have been examined since these test statistics are easily derived in the instrumental variable estimation framework. Savin (1976) has shown that inequalities exist among the test statistics for the linear hypothesis, but it is well known that there is no systematic inequality among these statistics based on 2SLSE for the linear hypothesis in a structural equation model. Morimune and Oya (1994) derived the constrained limited information maximum likelihood estimator (LIMLE) subject to general linear constraints on the coefficients of the structural equation, as well as Wald, LM and Lr Test statistics for the adequacy of the linear constraints.

In this paper, we derive the inequalities among these three test statistics based on LIMLE and the local power functions based on Limle and 2SLSE to show that there is no test statistic which is uniformly most powerful, and the LR test statistic based on LIMLE is locally unbised and the other test statistics are not. Monte Carlo simulations are used to examine the actual sizes of these test statistics and some numerical examples of the power differences among these test statistics are given. It is found that the actual sizes of these test statistics are greater than the nominal sizes, the differences between the actual and nominal sizes of Wald test statistics are generally the greatest, those of LM test statistics are the smallest, and the power functions depend on the correlations between the endogenous explanatory variables and the error term of the structural equation, the asymptotic variance of estimator of coefficients of the structural equation and the number of restrictions imposed on the coefficients.     

Exact Tests for 2 × 2 Contingency Tables

Fisher's exact test, difference in proportions, log odds ratio, Pearson's chi-squared, and likelihood ratio are compared as test statistics for testing independence of two dichotomous factors when the associated p values are computed by using the conditional distribution given the marginals. The statistics listed above that can be used for a one-sided alternative give identical p values. For a two-sided alternative, many of the above statistics lead to different p values. The p values are shown to differ only by which tables in the opposite tail from the observed table are considered more extreme than the observed table.     

A new generalized p-value approach for testing equality of coefficients of variation in k normal populations

A new generalized p-value method is proposed for testing the equality of coefficients of variation in k normal populations. Simulation studies show that the type I error probabilities are close to the nominal level. The proposed test is also compared with likelihood ratio test, modified Bennett's test and score test through Monte Carlo simulation, the results demonstrate that the generalized p-value method has satisfactory performance in terms of sizes and powers.     

Conditional Tests for censored matched pairs

A class of statistics is proposed for the problem of testing for location difference using randomly right censored matched pair data. Each member of the class provides a conditionally distribution-free test of H₀: no location difference. Simulation results indicate that powers tests basd on certain members in the class are as good as or better thatn the power of a test proposed by Woolson and Lachenbruch (1980).