ON CONFIDENCE INTERVALS FOR GENERALIZED ADDITIVE MODELS BASED ON PENALIZED REGRESSION SPLINES

Generalized additive models represented using low rank penalized regression splines, estimated by penalized likelihood maximisation and with smoothness selected by generalized cross validation or similar criteria, provide a computationally efficient general framework for practical smooth modelling. Various authors have proposed approximate Bayesian interval estimates for such models, based on extensions of the work of Wahba, G. (1983) [Bayesian confidence intervals for the cross validated smoothing spline. J. R. Statist. Soc. B 45 , 133–150] and Silverman, B.W. (1985) [Some aspects of the spline smoothing approach to nonparametric regression curve fitting. J. R. Statist. Soc. B 47 , 1–52] on smoothing spline models of Gaussian data, but testing of such intervals has been rather limited and there is little supporting theory for the approximations used in the generalized case. This paper aims to improve this situation by providing simulation tests and obtaining asymptotic results supporting the approximations employed for the generalized case. The simulation results suggest that while across‐the‐model performance is good, component‐wise coverage probabilities are not as reliable. Since this is likely to result from the neglect of smoothing parameter variability, a simple and efficient simulation method is proposed to account for smoothing parameter uncertainty: this is demonstrated to substantially improve the performance of component‐wise intervals.     

Coverage Properties of Confidence Intervals for Generalized Additive Model Components

Abstract. We study the coverage properties of Bayesian confidence intervals for the smooth component functions of generalized additive models (GAMs) represented using any penalized regression spline approach. The intervals are the usual generalization of the intervals first proposed by Wahba and Silverman in 1983 and 1985, respectively, to the GAM component context. We present simulation evidence showing these intervals have close to nominal ‘across‐the‐function’ frequentist coverage probabilities, except when the truth is close to a straight line/plane function. We extend the argument introduced by Nychka in 1988 for univariate smoothing splines to explain these results. The theoretical argument suggests that close to nominal coverage probabilities can be achieved, provided that heavy oversmoothing is avoided, so that the bias is not too large a proportion of the sampling variability. The theoretical results allow us to derive alternative intervals from a purely frequentist point of view, and to explain the impact that the neglect of smoothing parameter variability has on confidence interval performance. They also suggest switching the target of inference for component‐wise intervals away from smooth components in the space of the GAM identifiability constraints.     

Nonparametric estimation of quantile functions for randomly right censored data

In this paper we compare four nonparametric quantile function estimators for randomly right censored data: the Kaplan–Meier estimator, the linearly interpolated Kaplan–Meier estimator, the kernel-type survival function estimator, and the Bézier curve smoothing estimator. Also, we compare several kinds of confidence intervals of quantiles for four nonparametric quantile function estimators.     

Nonparametric confidence intervals for quantiles and quantile intervals from inversely sampled record breaking data in a multi-sample plan

There are a number of situations in which an observation is retained only if it is a record value, which include studies in industrial quality control experiments, destructive stress testing, meteorology, hydrology, seismology, athletic events and mining. When the number of records is fixed in advance, the data are referred to as inversely sampled record-breaking data. In this paper, we study the problems of constructing the nonparametric confidence intervals for quantiles and quantile intervals of the parent distribution based on record data. For a single record-breaking sample, the confidence coefficients of the confidence intervals for the pth quantile cannot exceed p and 1?p, on the basis of upper and lower records, respectively; hence, replication is required. So, we develop the procedure based on k independent record-breaking samples. Various cases have been studied and in each case, the optimal k and the exact nonparametric confidence intervals are obtained, and exact expressions for the confidence coefficients of these confidence intervals are derived. Finally, the results are illustrated by numerical computations.     

New bootstrap confidence intervals for means of positively skewed distributions

ABSTRACT

In this paper, we consider the problem of constructing non parametric confidence intervals for the mean of a positively skewed distribution. We suggest calibrated, smoothed bootstrap upper and lower percentile confidence intervals. For the theoretical properties, we show that the proposed one-sided confidence intervals have coverage probability α + O(n^{? 3/2}). This is an improvement upon the traditional bootstrap confidence intervals in terms of coverage probability. A version smoothed approach is also considered for constructing a two-sided confidence interval and its theoretical properties are also studied. A simulation study is performed to illustrate the performance of our confidence interval methods. We then apply the methods to a real data set.     

Focused information criterion and model averaging based on weighted composite quantile regression

We study the focused information criterion and frequentist model averaging and their application to post‐model‐selection inference for weighted composite quantile regression (WCQR) in the context of the additive partial linear models. With the non‐parametric functions approximated by polynomial splines, we show that, under certain conditions, the asymptotic distribution of the frequentist model averaging WCQR‐estimator of a focused parameter is a non‐linear mixture of normal distributions. This asymptotic distribution is used to construct confidence intervals that achieve the nominal coverage probability. With properly chosen weights, the focused information criterion based WCQR estimators are not only robust to outliers and non‐normal residuals but also can achieve efficiency close to the maximum likelihood estimator, without assuming the true error distribution. Simulation studies and a real data analysis are used to illustrate the effectiveness of the proposed procedure.     

Empirical Likelihood Intervals for Conditional Value‐at‐Risk in Heteroscedastic Regression Models

Abstract. Non‐parametric regression models have been studied well including estimating the conditional mean function, the conditional variance function and the distribution function of errors. In addition, empirical likelihood methods have been proposed to construct confidence intervals for the conditional mean and variance. Motivated by applications in risk management, we propose an empirical likelihood method for constructing a confidence interval for the pth conditional value‐at‐risk based on the non‐parametric regression model. A simulation study shows the advantages of the proposed method.     

ON THE COVERAGE PROBABILITY OF CONFIDENCE INTERVALS IN REGRESSION AFTER VARIABLE SELECTION

This paper considers a linear regression model with regression parameter vector β. The parameter of interest is θ= a^Tβ where a is specified. When, as a first step, a data‐based variable selection (e.g. minimum Akaike information criterion) is used to select a model, it is common statistical practice to then carry out inference about θ, using the same data, based on the (false) assumption that the selected model had been provided a priori. The paper considers a confidence interval for θ with nominal coverage 1 ‐ α constructed on this (false) assumption, and calls this the naive 1 ‐ α confidence interval. The minimum coverage probability of this confidence interval can be calculated for simple variable selection procedures involving only a single variable. However, the kinds of variable selection procedures used in practice are typically much more complicated. For the real‐life data presented in this paper, there are 20 variables each of which is to be either included or not, leading to 2²⁰ different models. The coverage probability at any given value of the parameters provides an upper bound on the minimum coverage probability of the naive confidence interval. This paper derives a new Monte Carlo simulation estimator of the coverage probability, which uses conditioning for variance reduction. For these real‐life data, the gain in efficiency of this Monte Carlo simulation due to conditioning ranged from 2 to 6. The paper also presents a simple one‐dimensional search strategy for parameter values at which the coverage probability is relatively small. For these real‐life data, this search leads to parameter values for which the coverage probability of the naive 0.95 confidence interval is 0.79 for variable selection using the Akaike information criterion and 0.70 for variable selection using Bayes information criterion, showing that these confidence intervals are completely inadequate.     

Corrected profile likelihood confidence interval for binomial paired incomplete data

Clinical trials often use paired binomial data as their clinical endpoint. The confidence interval is frequently used to estimate the treatment performance. Tang et al. (2009) have proposed exact and approximate unconditional methods for constructing a confidence interval in the presence of incomplete paired binary data. The approach proposed by Tang et al. can be overly conservative with large expected confidence interval width (ECIW) in some situations. We propose a profile likelihood‐based method with a Jeffreys' prior correction to construct the confidence interval. This approach generates confidence interval with a much better coverage probability and shorter ECIWs. The performances of the method along with the corrections are demonstrated through extensive simulation. Finally, three real world data sets are analyzed by all the methods. Statistical Analysis System (SAS) codes to execute the profile likelihood‐based methods are also presented. Copyright © 2013 John Wiley & Sons, Ltd.     

Boundary corrected cubic smoothing splines

Smoothing splines are known to exhibit a type of boundary bias that can reduce their estimation efficiency. In this paper, a boundary corrected cubic smoothing spline is developed in a way that produces a uniformly fourth order estimator. The resulting estimator can be calculated efficiently using an O(n) algorithm that is designed for the computation of fitted values and associated smoothing parameter selection criteria. A simulation study shows that use of the boundary corrected estimator can improve estimation efficiency in finite samples. Applications to the construction of asymptotically valid pointwise confidence intervals are also investigated .     

Nonparametric estimation of a log-variance function in scale-space

In a nonparametric regression setting, we consider the kernel estimation of the logarithm of the error variance function, which might be assumed to be homogeneous or heterogeneous. The objective of the present study is to discover important features in the variation of the data at multiple locations and scales based on a nonparametric kernel smoothing technique. Traditional kernel approaches estimate the function by selecting an optimal bandwidth, but it often turns out to be unsatisfying in practice. In this paper, we develop a SiZer (SIgnificant ZERo crossings of derivatives) tool based on a scale-space approach that provides a more flexible way of finding meaningful features in the variation. The proposed approach utilizes local polynomial estimators of a log-variance function using a wide range of bandwidths. We derive the theoretical quantile of confidence intervals in SiZer inference and also study the asymptotic properties of the proposed approach in scale-space. A numerical study via simulated and real examples demonstrates the usefulness of the proposed SiZer tool.     

Statistical inference for the quintile share ratio

In recent years, the Quintile Share Ratio (or QSR) has become a very popular measure of inequality. In 2001, the European Council decided that income inequality in European Union member states should be described using two indicators: the Gini Index and the QSR. The QSR is generally defined as the ratio of the total income earned by the richest 20% of the population relative to that earned by the poorest 20%. Thus, it can be expressed using quantile shares, where a quantile share is the share of total income earned by all of the units up to a given quantile. The aim of this paper is to propose an improved methodology for the estimation and variance estimation of the QSR in a complex sampling design framework. Because the QSR is a non-linear function of interest, the estimation of its sampling variance requires advanced methodology. Moreover, a non-trivial obstacle in the estimation of quantile shares in finite populations is the non-unique definition of a quantile. Thus, two different conceptions of the quantile share are presented in the paper, leading us to two different estimators of the QSR. Regarding variance estimation, [Osier, 2006] and [Osier, 2009] proposed a variance estimator based on linearization techniques. However, his method involves Gaussian kernel smoothing of cumulative distribution functions. Our approach, also based on linearization, shows that no smoothing is needed. The construction of confidence intervals is discussed and a proposition is made to account for the skewness of the sampling distribution of the QSR. Finally, simulation studies are run to assess the relevance of our theoretical results.     

A flexible procedure for formulating probability distributions on the unit interval with applications

Abstract

In this paper, we present a flexible mechanism for constructing probability distributions on a bounded intervals which is based on the composition of the baseline cumulative probability function and the quantile transformation from another cumulative probability distribution. In particular, we are interested in the (0, 1) intervals. The composite quantile family of probability distributions contains many models that have been proposed in the recent literature and new probability distributions are introduced on the unit interval. The proposed methodology is illustrated with two examples to analyze a poverty dataset in Peru from the Bayesian paradigm and Likelihood points of view.     

Exact average coverage probabilities and confidence coefficients of confidence intervals for discrete distributions

For a confidence interval (L(X),U(X)) of a parameter θ in one-parameter discrete distributions, the coverage probability is a variable function of θ. The confidence coefficient is the infimum of the coverage probabilities, inf  _θ P _θ (θ∈(L(X),U(X))). Since we do not know which point in the parameter space the infimum coverage probability occurs at, the exact confidence coefficients are unknown. Beside confidence coefficients, evaluation of a confidence intervals can be based on the average coverage probability. Usually, the exact average probability is also unknown and it was approximated by taking the mean of the coverage probabilities at some randomly chosen points in the parameter space. In this article, methodologies for computing the exact average coverage probabilities as well as the exact confidence coefficients of confidence intervals for one-parameter discrete distributions are proposed. With these methodologies, both exact values can be derived.     

Nonparametric estimation of varying-coefficient single-index models

The varying-coefficient single-index model has two distinguishing features: partially linear varying-coefficient functions and a single-index structure. This paper proposes a nonparametric method based on smoothing splines for estimating varying-coefficient functions and an unknown link function. Moreover, the average derivative estimation method is applied to obtain the single-index parameter estimates. For interval inference, Bayesian confidence intervals were obtained based on Bayes models for varying-coefficient functions and the link function. The performance of the proposed method is examined both through simulations and by applying it to Boston housing data.     

Automatic Bayesian quantile regression curve fitting

Quantile regression, including median regression, as a more completed statistical model than mean regression, is now well known with its wide spread applications. Bayesian inference on quantile regression or Bayesian quantile regression has attracted much interest recently. Most of the existing researches in Bayesian quantile regression focus on parametric quantile regression, though there are discussions on different ways of modeling the model error by a parametric distribution named asymmetric Laplace distribution or by a nonparametric alternative named scale mixture asymmetric Laplace distribution. This paper discusses Bayesian inference for nonparametric quantile regression. This general approach fits quantile regression curves using piecewise polynomial functions with an unknown number of knots at unknown locations, all treated as parameters to be inferred through reversible jump Markov chain Monte Carlo (RJMCMC) of Green (Biometrika 82:711–732, 1995). Instead of drawing samples from the posterior, we use regression quantiles to create Markov chains for the estimation of the quantile curves. We also use approximate Bayesian factor in the inference. This method extends the work in automatic Bayesian mean curve fitting to quantile regression. Numerical results show that this Bayesian quantile smoothing technique is competitive with quantile regression/smoothing splines of He and Ng (Comput. Stat. 14:315–337, 1999) and P-splines (penalized splines) of Eilers and de Menezes (Bioinformatics 21(7):1146–1153, 2005).     

The Coverage Probability of Confidence Intervals in One‐Way Analysis of Covariance after Two F Tests

Volume 3 of Analysis of Messy Data by Milliken & Johnson (2002) provides detailed recommendations about sequential model development for the analysis of covariance. In his review of this volume, Koehler (2002) asks whether users should be concerned about the effect of this sequential model development on the coverage probabilities of confidence intervals for comparing treatments. We present a general methodology for the examination of these coverage probabilities in the context of the two‐stage model selection procedure that uses two F tests and is proposed in Chapter 2 of Milliken & Johnson (2002). We apply this methodology to an illustrative example from this volume and show that these coverage probabilities are typically very far below nominal. Our conclusion is that users should be very concerned about the coverage probabilities of confidence intervals for comparing treatments constructed after this two‐stage model selection procedure.     

A note on asymptotics for quantile smoothing splines

When cubic smoothing splines are used to estimate the conditional quantile function, thereby balancing fidelity to the data with a smoothness requirement, the resulting curve is the solution to a quadratic program. Using this quadratic characterization and through comparison with the sample conditional quan-tiles, we show strong consistency and asymptotic normality for the quantile smoothing spline.     

Sparse conformal predictors

Conformal predictors, introduced by Vovk et al. (Algorithmic Learning in a Random World, Springer, New York, 2005), serve to build prediction intervals by exploiting a notion of conformity of the new data point with previously observed data. We propose a novel method for constructing prediction intervals for the response variable in multivariate linear models. The main emphasis is on sparse linear models, where only few of the covariates have significant influence on the response variable even if the total number of covariates is very large. Our approach is based on combining the principle of conformal prediction with the ℓ ₁ penalized least squares estimator (LASSO). The resulting confidence set depends on a parameter ε>0 and has a coverage probability larger than or equal to 1−ε. The numerical experiments reported in the paper show that the length of the confidence set is small. Furthermore, as a by-product of the proposed approach, we provide a data-driven procedure for choosing the LASSO penalty. The selection power of the method is illustrated on simulated and real data.     

Quantile inference for heteroscedastic regression models

Consider the nonparametric heteroscedastic regression model Y=m(X)+σ(X)?, where m(·) is an unknown conditional mean function and σ(·) is an unknown conditional scale function. In this paper, the limit distribution of the quantile estimate for the scale function σ(X) is derived. Since the limit distribution depends on the unknown density of the errors, an empirical likelihood ratio statistic based on quantile estimator is proposed. This statistics is used to construct confidence intervals for the variance function. Under certain regularity conditions, it is shown that the quantile estimate of the scale function converges to a Brownian motion and the empirical likelihood ratio statistic converges to a chi-squared random variable. Simulation results demonstrate the superiority of the proposed method over the least squares procedure when the underlying errors have heavy tails.