The generalized Cucconi test statistic for the two-sample problem

When testing hypotheses in two-sample problem, the Lepage test statistic is often used to jointly test the location and scale parameters, and this test statistic has been discussed by many authors over the years. Since two-sample nonparametric testing plays an important role in biometry, the Cucconi test statistic is generalized to the location, scale, and location–scale parameters in two-sample problem. The limiting distribution of the suggested test statistic is derived under the hypotheses. Deriving the exact critical value of the test statistic is difficult when the sample sizes are increased. A gamma approximation is used to evaluate the upper tail probability for the proposed test statistic given finite sample sizes. The asymptotic efficiencies of the proposed test statistic are determined for various distributions. The consistency of the original Cucconi test statistic is shown on the specific cases. Finally, the original Cucconi statistic is discussed in the theory of ties.     

A random-sum Wilcoxon statistic and its application to analysis of ROC and LROC data

The Wilcoxon-Mann-Whitney statistic is commonly used for a distribution-free comparison of two groups. One requirement for its use is that the sample sizes of the two groups are fixed. This is violated in some of the applications such as medical imaging studies and diagnostic marker studies; in the former, the violation occurs since the number of correctly localized abnormal images is random, while in the latter the violation is due to some subjects not having observable measurements. For this reason, we propose here a random-sum Wilcoxon statistic for comparing two groups in the presence of ties, and derive its variance as well as its asymptotic distribution for large sample sizes. The proposed statistic includes the regular Wilcoxon rank-sum statistic. Finally, we apply the proposed statistic for summarizing location response operating characteristic data from a liver computed tomography study, and also for summarizing diagnostic accuracy of biomarker data.     

A Modification on the Friedman Test Statistic

A modification on the well-known, nonparametric Friedman test statistic is suggested in this article. Probability distributions of the suggested test statistic under the null hypothesis are tabulated for some small sample cases. In addition to an example, simulation results for various sample sizes are presented. The simulation indicates that the modified test statistic performs better than the Friedman test in detecting treatment effects of small differences especially when the sample size is small.     

Notes on Kolassa’s Method for Estimating the Power of Wilcoxon–Mann–Whitney Test

The Kolassa method implemented in the nQuery Advisor software has been widely used for approximating the power of the Wilcoxon–Mann–Whitney (WMW) test for ordered categorical data, in which Edgeworth approximation is used to estimate the power of an unconditional test based on the WMW U statistic. When the sample size is small or when the sizes in the two groups are unequal, Kolassa’s method may yield quite poor approximation to the power of the conditional WMW test that is commonly implemented in statistical packages. Two modifications of Kolassa’s formula are proposed and assessed by simulation studies.     

A continuously adaptive nonparametric two–sample test

A two–sample test statistic for detecting shifts in location is developed for a broad range of underlying distributions using adaptive techniques. The test statistic is a linear rank statistics which uses a simple modification of the Wilcoxon test; the scores are Winsorized ranks where the upper and lower Winsorinzing proportions are estimated in the first stage of the adaptive procedure using sample the first stage of the adaptive procedure using sample measures of the distribution's skewness and tailweight. An empirical relationship between the Winsorizing proportions and the sample skewness and tailweight allows for a ‘continuous’ adaptation of the test statistic to the data. The test has good asymptotic properties, and the small sample results are compared with other populatr parametric, nonparametric, and two–stage tests using Monte Carlo methods. Based on these results, this proposed test procedure is recommended for moderate and larger sample sizes.     

An exact two-sample test based on the baumgartner-weiss-schindler statistic and a modification of lepage's test

It is shown that the nonparametric two-saniDle test recently proposed by Baumgartner, WeiB, Schindler (1998, Biometrics, 54, 1129-1135) does not control the type I error rate in case of small sample sizes. We investigate the exact permutation test based on their statistic and demonstrate that this test is almost not conservative. Comparing exact tests, the procedure based on the new statistic has a less conservative size and is, according to simulation results, more powerful than the often employed Wilcoxon test. Furthermore, the new test is also powerful with regard to less restrictive settings than the location-shift model. For example, the test can detect location-scale alternatives. Therefore, we use the test to create a powerful modification of the nonparametric location-scale test according to Lepage (1971, Biometrika, 58, 213-217). Selected critical values for the proposed tests are given.     

A note on the nonparametric test based on theL 1-version of the Cramér-von Mises statistic

We consider the test based on theL ₁-version of the Cramér-von Mises statistic for the nonparametric two-sample problem. Some quantiles of the exact distribution under H₀ of the test statistic are computed for small sample sizes. We compare the test in terms of power against general alternatives to other two-sample tests, namely the Wilcoxon rank sum test, the Smirnov test and the Cramér-von Mises test in the case of unbalanced small sample sizes. The computation of the power is rather complicated when the sample sizes are unequal. Using Monte Carlo power estimates it turns out that the Smirnov test is more sensitive to non stochastically ordered alternatives than the new test. And under location-contamination alternatives the power estimates of the new test and of the competing tests are equal.     

On the asymptotic normality and other large sample properties of grenander's mode estimator

The problem of estimating the mode of a continuous distribution has received considerable attention in recent years. Grenander (1965) has proposed a direct estimator of the mode based on the intuitive idea that raising a density to a positive power will make the mode more pronounced and, hence, easier to estimate. Grenander shows his estimator is weakly consistent and conjectures that it is also asymptotically normal. The analytical complexity of the estimator makes a mathematical study of this conjecture quite difficult. Another approach is to conduct goodness-of-fit studies to see how well the normal distribution approximates the sampling distribution of the estimator for various sample sizes and underlying parent distributions. The results of the study are presented where the main inferential tools were a Kolmogorov–Smirnov test statistic and a modified Shapiro–Wilk test statistic. The results of a simulation study exploring other large sample properties of the estimator (and a modification) are also given.     

Modification of the kolmogorov-smirnov test for the erlang-2 distribution

An adjusted Kolmogorov-Smirnov statistic and critical values are developed for the Erlang-2 probability distribution using data from Monte Carlo simulations. The process used is similar to that of Stephens in the 1970s. The test statistic produced features of compactness and ease of implementation. It is quite accurate for sample sizes as low as ten.     

Application of Anbar's Approach to Hypothesis Testing to Detect the Difference between Two Proportions

In this paper, Anbar's (1983) approach for estimating a difference between two binomial proportions is discussed with respect to a hypothesis testing problem. Such an approach results in two possible testing strategies. While the results of the tests are expected to agree for a large sample size when two proportions are equal, the tests are shown to perform quite differently in terms of their probabilities of a Type I error for selected sample sizes. Moreover, the tests can lead to different conclusions, which is illustrated via a simple example; and the probability of such cases can be relatively large. In an attempt to improve the tests while preserving their relative simplicity feature, a modified test is proposed. The performance of this test and a conventional test based on normal approximation is assessed. It is shown that the modified Anbar's test better controls the probability of a Type I error for moderate sample sizes.     

A test for bivariate two sample location problem

A consistent test for difference in locations between two bivariate populations is proposed, The test is similar as the Mann-Whitney test and depends on the exceedances of slopes of the two samples where slope for each sample observation is computed by taking the ratios of the observed values. In terms of the slopes, it reduces to a univariate problem, The power of the test has been compared with those of various existing tests by simulation. The proposed test statistic is compared with Mardia's(1967) test statistics, Peters-Randies(1991) test statistic, Wilcoxon's rank sum test. statistic and Hotelling' T² test statistic using Monte Carlo technique. It performs better than other statistics compared for small differences in locations between two populations when underlying population is population 7(light tailed population) and sample size 15 and 18 respectively. When underlying population is population 6(heavy tailed population) and sample sizes are 15 and 18 it performas better than other statistic compared except Wilcoxon's rank sum test statistics for small differences in location between two populations. It performs better than Mardia's(1967) test statistic for large differences in location between two population when underlying population is bivariate normal mixture with probability p=0.5, population 6, Pearson type II population and Pearson type VII population for sample size 15 and 18 .Under bivariate normal population it performs as good as Mardia' (1967) test statistic for small differences in locations between two populations and sample sizes 15 and 18. For sample sizes 25 and 28 respectively it performs better than Mardia's (1967) test statistic when underlying population is population 6, Pearson type II population and Pearson type VII population     

The analysis of multicentre clinical trials when there is heterogeneity between centres

Two-treatment multicentre clinical trials are very common in practice. In cases where a non-parametric analysis is appropriate, a rank-sum test for grouped data called the van Elteren test can be applied. As an alternative approach, one may apply a combination test such as Fisher's combination test or the inverse normal combination test (also called Liptak's method) in order to combine centre-specific P-values. If there are no ties and no differences between centres with regard to the groups’ sample sizes, the inverse normal combination test using centre-specific Wilcoxon rank-sum tests is equivalent to the van Elteren test. In this paper, the van Elteren test is compared with Fisher's combination test based on Wilcoxon rank-sum tests. Data from two multicentre trials as well as simulated data indicate that Fisher's combination of P-values is more powerful than the van Elteren test in realistic scenarios, i.e. when there are large differences between the centres’ P-values, some quantitative interaction between treatment and centre, and/or heterogeneity in variability. The combination approach opens the possibility of using statistics other than the rank sum, and it is also a suitable method for more complicated designs, e.g. when covariates such as age or gender are included in the analysis.     

Improving the brown-forsythe solution to the generalized behrens-fisher problem

Over two decades ago, Brown and Forsythe (B-F) (1974) proposed an innovative solution to the problem of comparing independent normal means under heteroscedasticity. Since then, their testing procedure has gained in popularity and authors have published various articles in which the B-F test has formed the basis of their research. The purpose of this paper is to point out, and correct, a flaw in the B-F testing procedure. Specifically, it is shown that the approximation proposed by B-F for the null distribution of their test statistic is inadequate. An improved approximation is provided and the small sample null properties of the modified B-F test are studied via simulation. The empirical findings support the theoretical result that the modified B-F test does a better job of preserving the test size compared to the original B-F test.     

A Generalization of Ahmad's Class of Mann–Whitney–Wilcoxon Statistics

In the spirit of the recent work of Ahmad (1996) this paper introduces another class of Mann–Whitney–Wilcoxon test statistics. The test statistic compares the r th and s th powers of the tail probabilities of the underlying probability distributions. The choice of r + s = 4 improves the Pitman efficiency for uniform, exponential, lognormal and normal distributions and keeps the same efficiency as the Mann–Whitney–Wilcoxon test for logistic and double exponential distributions. The two-sample test is modified for the one-sample problem with symmetric underlying distribution.     

Critical Values for the Robust Rank-Order Test

ABSTRACT

The nonparametric Wilcoxon–Mann–Whitney test is commonly used by practitioners for detecting differences in location (mean, median) between two samples. Earlier work has shown this test to have a number of disadvantages, most of which are remedied by use of the alternative robust rank-order test. Use of the robust rank-order test has been limited, perhaps partly because exact critical values have up to now been available for only a small number of sample-size values, and not for all of the commonly used levels of significance. This article expands what is known about the distribution of the robust rank-order test statistic; critical values are given for more sample sizes and for more levels of significance.     

Book Reviews

The Levene test is a widely used test for detecting differences in dispersion. The modified Levene transformation using sample medians is considered in this article. After Levene's transformation the data are not normally distributed, hence, nonparametric tests may be useful. As the Wilcoxon rank sum test applied to the transformed data cannot control the type I error rate for asymmetric distributions, a permutation test based on reallocations of the original observations rather than the absolute deviations was investigated. Levene's transformation is then only an intermediate step to compute the test statistic. Such a Levene test, however, cannot control the type I error rate when the Wilcoxon statistic is used; with the Fisher–Pitman permutation test it can be extremely conservative. The Fisher–Pitman test based on reallocations of the transformed data seems to be the only acceptable nonparametric test. Simulation results indicate that this test is on average more powerful than applying the t test after Levene's transformation, even when the t test is improved by the deletion of structural zeros.     

A moment-based empirical likelihood ratio test for exponentiality using the probability integral transformation

ABSTRACT

A simple and efficient goodness-of-fit test for exponentiality is developed by exploiting the characterization of the exponential distribution using the probability integral transformation. We adopted the empirical likelihood methodology in constructing the test statistic. The proposed test statistic has a chi-square limiting distribution. For small to moderate sample sizes Monte-Carlo simulations revealed that our proposed tests are much more superior under increasing failure rate (IFR) and bathtub decreasing-increasing failure rate (BFR) alternatives. Real data examples were used to demonstrate the robustness and applicability of our proposed tests in practice.     

P-values for the multi-sample kolmogorov-smirnov test using the expanded bonferroni appoximation

Birnbaum and Hall (1960) introduced a natural statistic for a k-sample generlization of the Kolomogorov-Smirnov test. Using an expansion of Bonferroni's Inequality, this paper determines approximate p-values for the Birnbaum and Hall statistic up to ten samples. This approximation is found to be very accurate under most circumstances. The statistic is also generalized to unequal sample sizes. An example of its use is presented.     

A Bayesian analysis for the Wilcoxon signed-rank statistic

A Bayesian analysis is provided for the Wilcoxon signed-rank statistic (T⁺). The Bayesian analysis is based on a sign-bias parameter φ on the (0, 1) interval. For the case of a uniform prior probability distribution for φ and for small sample sizes (i.e., 6 ? n ? 25), values for the statistic T⁺ are computed that enable probabilistic statements about φ. For larger sample sizes, approximations are provided for the asymptotic likelihood function P(T⁺|φ) as well as for the posterior distribution P(φ|T⁺). Power analyses are examined both for properly specified Gaussian sampling and for misspecified non Gaussian models. The new Bayesian metric has high power efficiency in the range of 0.9–1 relative to a standard t test when there is Gaussian sampling. But if the sampling is from an unknown and misspecified distribution, then the new statistic still has high power; in some cases, the power can be higher than the t test (especially for probability mixtures and heavy-tailed distributions). The new Bayesian analysis is thus a useful and robust method for applications where the usual parametric assumptions are questionable. These properties further enable a way to do a generic Bayesian analysis for many non Gaussian distributions that currently lack a formal Bayesian model.     

Small sample distribution for a nonparametric test for trend

The exact distribution of a nonparametric test statistic for ordered alternatives, the _rank ² statistic, is computed for small sample sizes. The exact distribution is compared to an approximation.