Two-Patch Transmission of Tuberculosis

For a two-patch transmission of tuberculosis (TB), the disease-free equilibrium and the basic reproduction rate ?₀ are computed. The disease-free equilibrium is globally asymptotically stable when the basic reproduction rate is less than one. The model can have one or more endemic equilibria. The increased progression rate from latent to active TB in one population may play a significant role in the rising prevalence of TB in the other population. The increased migration from the first to the second population increases the prevalence level of TB in the second population and decreases the TB prevalence in the first population.     

Bayesian Estimation for Quantification by Real-time Polymerase Chain Reaction Under a Branching Process Model of the DNA Molecules Amplification Process

The aim of Quantitative Polymerase Chain Reaction is to determine the initial amount X ₀ of specific nucleic acids from an observed trajectory of the amplification process, the amplification being achieved through successive replication cycles. This process depends on the efficiency {p _n } _n of replication of the DNA molecules, p _n being the probability that a molecule will duplicate at replication cycle n. Assuming p _n  = p for all n, Bayesian estimators of the unknown parameter θ = (p, X ₀) are constructed by Markov Chain Monte Carlo methods under a Bienaymé-Galton-Watson branching model of the amplification process. The Bayesian approach takes into account some prior information on the parameter. Relying on simulated data, the proposed Bayesian estimators and their credibility sets are shown to be quite accurate.     

On a Pandemic Threshold Theorem of the Early Kermack–McKendrick Model with Individual Heterogeneity

A pandemic threshold theorem of the Kermack–McKendrick epidemic system with individual heterogeneity is proved from the definition of R ₀ by Diekmann, Heesterbeek, and Metz. The early Kermack–McKendrick epidemic model is extended to recognize individual heterogeneity, where the state variable indicates an epidemiological state or genetic, physiological, or behavioral characteristics such as risk of infection. With the basic reproduction number R ₀ for the heterogeneous population, the final size equation of the limit epidemic starting from a completely susceptible steady state at t = ?∞ has a unique positive solution if and only if R ₀  > 1. The main result is that the positive solution of the final size equation gives the lower bound of the intensity of any epidemic starting from a host population composed of susceptible and a few infected individuals who spread on a noncompact domain of the trait variable.     

Stability Analysis and Dynamics Preserving Nonstandard Finite Difference Schemes for a Malaria Model

When both human and mosquito populations vary, forward bifurcation occurs if the basic reproduction number R ₀ is less than one in the absence of disease-induced death. When the disease-induced death rate is large enough, R ₀ = 1 is a subcritical backward bifurcation point. The domain for the study of the dynamics is reduced to a compact and feasible region, where the system admits a specific algebraic decomposition into infective and non-infected humans and mosquitoes. Stability results are extended and the possibility of backward bifurcation is clarified. A dynamically consistent nonstandard finite difference scheme is designed.     

Body image,satisfaction with sexual life,self-esteem,and anxiodepressive symptoms: A comparative study between premenopausal,perimenopausal, and postmenopausal women

Menopause is an important life transition in women, and it is associated with significant physical and psychological changes. This study aimed at examining how the menopausal transition influences body image and satisfaction with sexual life. To this aim, body image dissatisfaction, sexual dissatisfaction, and self-esteem were compared in three groups of women with distinct menopausal status (premenopausal n = 142, perimenopausal n = 66, or postmenopausal n = 149), while controlling for depressive and anxiety symptoms and BMI. Using ANOVA between these three groups, we observed that dissatisfaction with body image was significantly higher in the perimenopausal sample compared with its premenopausal counterpart. In the postmenopausal sample, body image improved, as this group displayed body image scores close to the premenopausal level. In addition, sexual dissatisfaction was significantly increased in the perimenopausal and postmenopausal samples, which is compatible with the concept that higher body appreciation positively predicted sexual function. We conclude that body image dissatisfaction reaches a maximum during the perimenopausal phase, before returning to a level nearly identical between the premenopausal and the postmenopausal phases.     

“Hedge Your Bets”: Technology’s Role in Young Gay Men’s Relationship Challenges

Technology is playing an increasingly pervasive role among young gay men in the process of meeting potential romantic or sexual partners. We investigated challenges posed by technology related to young gay men’s relationships. Focus groups (n = 9) of young gay men aged 18–24 (n = 43) were transcribed verbatim, and thematic analysis was used to identify two major themes regarding challenges to relationship development and maintenance. Subthemes include unrealistic expectations of relationships, inauthentic self-presentation online, sexual primacy over romance, increased opportunities for infidelity, and jealousy. The implications of this study for sexual education and sexual health promotion are discussed.     

When “They” Become “Us”: The Effect of Time and Ingroup Identity on Perceptions of Gay and Lesbian Group Members

ABSTRACT

Prejudice change manipulations rarely produce the expected attitude change effects. Our research suggests that attitude change depends on time-dependent memory consolidation processes. This study tested the effects of group information and time on perceptions of gays and lesbians. Heterosexual participants (N = 90) were randomly assigned to a condition where their ingroup, or an outgroup, included gay and lesbian individuals. We measured participants’ gay and lesbian political attitudes and evaluations of the groups’ members at a short or long delay. Results showed no effect of our manipulations on political attitudes, F(1, 86) = 0.14, p = .72. Contrary to predictions, participants evaluated gay and lesbian ingroup members less positively at the long versus short delay, t(49) = 3.72, p = .0004, d = 1.01. Results suggest that members of stigmatized groups are perceived more negatively when associated with one’s ingroup.     

Assessing the Gender Invariance of the Modern Homonegativity Scale

The measurement invariance of the Modern Homonegativity Scale (MHS) was examined among heterosexual female (n = 449) and male (n = 329) university students who were predominantly Mexican American. The MHS demonstrated full invariance of factor loadings and partial invariance of latent intercepts. At the latent mean level, heterosexual men compared to heterosexual women held more negative attitudes toward both gay men and lesbian women. There were no latent mean differences in attitudes toward gay men and lesbian women when rated by either heterosexual men or heterosexual women. The MHS can be used by heterosexual men and heterosexual women to assess their homonegativity.     

A distance measure of spatial pattern in a biological population

Summary Suppose thatn individuals locate independently and randomly on a segment of line of finite length (habitat). Let the theoretical and observed ranges of the sites of the individuals on the segment be μ _n-1 andr _n-1, respectively. Then, the degree of dispersion of the individual sites is measured by the ratio, T _n =n _n-1/μ _n-1, as follows: A random spatial pattern forI _r−1 =1 An aggregated spatial pattern for 0≤I _r <1 A uniform spatial pattern for (n+1)/(n−1)≥I _r >1. Another method was derived. Let the probability that an observed range is less thanr _n−1 beI _p , under the hypothesis of a Beta distribution. Then indicates A random spatial pattern forI _p =1/2 An aggregated spatial pattern forI _p <1/2 A uniform spatial pattern forI _p >1/2. The first index can be used for comparing populations having the same number of individuals, whereas the second one can be used for comparing populations with different numbers of individuals.     

The Interrelations Between Internalized Homophobia,Depressive Symptoms,and Suicidal Ideation Among Australian Gay Men,Lesbians, and Bisexual Women

ABSTRACT

Internalized homophobia has been linked to depression among gay men, lesbians, and bisexuals. Relatively little research has investigated the link between internalized homophobia and suicidal thoughts and behaviors. The current research investigated the interrelations among internalized homophobia, depressive symptoms, and suicidal ideation by testing additive, mediation, and moderation models. Self-identified Australian gay men (n = 360), lesbians (n = 444), and bisexual women (n = 114) completed the Internalized Homophobia Scale, the Center for Epidemiological Studies Depression Scale, and the suicide subscale of the General Health Questionnaire. Results supported the additive and partial mediation models for gay men and the mediation and moderation models for lesbians. None of the models were supported for bisexual women. The findings imply that clinicians should focus on reducing internalized homophobia and depressive symptoms among gay men and lesbians, and depressive symptoms among bisexual women, to reduce suicidal ideation.     

The effectiveness of a group-based educational program on the self-efficacy and self-acceptance of menopausal women: A randomized controlled trial

This study aimed to assess the effectiveness of a group-based educational training on the self-efficacy and self-acceptance of Iranian menopausal women using the PRECEDE–PROCEED model. This Randomized Controlled Trial (RCT) was conducted on 80 menopausal women in the age range of 47–55 years residing in the northeast of Iran. The participants were divided randomly into a test group (n = 40) and a control group (n = 40). We found that designing and implementation of a group-based educational training according to the PRECEDE–PROCEED model can significantly enhance the knowledge and performance of the test group with regard to self-efficacy and self-acceptance.     

Some extensions of the keyfitz momentum relationship

A stable population, such that the total birthrateB(t) =B _o e ^ro^t, is abruptly altered by modifying the age-specific birth rate,m(x). The survivor function remains unaltered. The modified population ultimately settles down to a stable behavior, such thatB(t) =B ₁ e ^r ₁ ^t . It is shown thatB ₁/B ₀ = (R ₀ ?R ₁)/[(r ₀ ?r ₁)R ₀ Z ₁], whereR ₀,R ₁ are the net reproduction rates before and after the change, and \(\bar Z_1 \) expected age giving birth for the stable population after the change. The age structure and transients resulting from the change are also described. The effect of an abrupt change in the survivor functionl(x) is also investigated for the simple case where the change is caused by alteringl(x) toe ^?λx l(x). It is shown that the above ratio becomes \(B_1 /B_0 = N_1 /N_0 = [1 - \smallint _0^\infty e^{ - kx} g(x)dx]/\bar Z_1 \lambda \) , whereN refers to the numbers in the population,k =r ₀ + λ, andg(x) =m(x)l(x), the value before the change. A measure for the reproductive worth of the population is also established.     

Dynamics of Mixed Coalitions Under Social Cohesion Constraints

ABSTRACT

Parameters for the birth and death diffusion life table model subject to downward jumps randomly occurring at a constant rate are estimated. The jump magnitudes have a beta distribution with support [0, l_x ], where l_x is the total number of survivors prior to the jump. The estimation method is maximum likelihood. The Cramer–Rao Lower bound and the asymptotic distribution for the MLE are derived. The model is applied to the U.S. men′s population from 1900 to 1999.     

Seroadaptive Strategies of Vancouver Gay and Bisexual Men in a Treatment as Prevention Environment

British Columbia’s treatment as prevention policy has provided free access to highly active antiretroviral therapy (HAART) to all HIV-positive provincial residents since 1996. One outcome is an increase in HIV-positive gay and bisexual men (GBM) with suppressed viral loads. Previous cross-sectional analyses indicated that some Vancouver GBM now recognize condomless anal sex with men on HAART who report a suppressed viral load as a seroadaptive strategy. To test the hypothesis that this new strategy, termed viral load sorting (VLS), is recognized and used among by GBM in the Momentum Health Study, we analyzed longitudinal data for HIV-negative/unknown (n = 556) and HIV-positive (n = 218) serostatus participants. Analyses indicated that both groups reported VLS, and that serostatus and Treatment Optimism Scale scores were significant determinants in frequency and use. Results exemplify the medicalization of sex and Rogers’ Diffusion Of Preventative Innovations Model, and they have important implications for HIV research and GBM sexual decision-making.     

Exercise training in thermo-mineral spring water has beneficial effects on hemodynamic and health-related factors in young-older hypertensive women: A randomized control trial

ABSTRACT

The aim of the study was to evaluate the effects of an 8-week aerobic training in mineral geothermal water on hemodynamic variables, VO_2max, and body composition in sedentary hypertensive women. Twenty postmenopausal women (58.55 ± 3.28 years) were divided into an exercise group (2 days/week, 30–40 minutes, 60%–75% of HR_max) and control group. Compared to the control group, a signi?cant reduction in systolic blood pressure, heart rate, rate pressure product, body fat percent, and a signi?cant improvement in VO_2max values was found. Aerobic training in thermo-mineral spring water is a safe and effective training modality in the young-older hypertensive population.     

Assessing the Tongzhi Label: Self-Identification and Public Opinion

Tongzhi is one of several Chinese terms that refer to individuals who are attracted to the same sex. Using data from two different surveys in Hong Kong, this research note examines how the term tongzhi coexists with other terms. We investigate the prevalence of self-identification as tongzhi, and we explore the extent to which using the term tongzhi influences public attitudes toward gay people and gay rights. Activists began popularizing the term tongzhi in the late 1980s, but less than one third of the participants in our 2008 survey of sexual orientation minorities (n = 728) described themselves as tongzhi. Using a split-ballot experiment in a 2013 public opinion poll (n = 831), we found that attitudes toward gay people and gay rights were not significantly impacted by whether questions were phrased in terms of tongzhi or the main alternative term tongxinglianzhe. We discuss how our findings can enrich understandings of earlier research and illuminate avenues for future study.     

Seasonal and weather-related behavioral effects among urban Aboriginal, urban non-Aboriginal, and remote Aboriginal participants in Canada

The influence of seasonal change and weather on mood, social activity, weight, food consumption, and sleep length was compared across urban Aboriginals (n = 43), urban non-Aboriginals (n = 49), and remote Aboriginals (n = 39) in Ontario, Canada. Such research is important since climate change may differentially shape the well-being of social groups. Behavioral items—including mood, social activity, weight, sleep, and food consumption—were measured using the Seasonal Pattern Assessment Questionnaire, and associations between these items and meteorological data were examined with bivariate and multivariate approaches. Weather variables had consistent, significant associations with behavior except within the remote Aboriginal group despite living in a more extreme climate. Lifestyle and adaptation may contribute to an increased weather tolerance among remote Aboriginal people, intriguing findings as cultures grapple with the implications of future climate change.     

Development and Validation of the Transgender Inclusive Behavior Scale (TIBS)

Transgender-inclusive behaviors are actions and communication supporting transgender individuals. Examples include using language not reinforcing the gender binary, asking for and using correct pronouns, creation of spaces that welcome members of the transgender community, and acknowledging cisgender (non-transgender) privilege. A survey was developed measuring this behavior in individuals to examine the impact of transgender-inclusive behavior and the potential effect of interventions on promoting inclusive behavior. Data were collected utilizing an online survey (N = 1,051). The sample was split in half to run two sets of cases in a principal components analysis. Analysis of the full sample showed Cronbach’s alpha to be .93 (n = 918). Findings suggest that the Transgender Inclusive Behavior Scale (TIBS) may be a useful instrument for identifying behaviors related to being inclusive of transgender individuals, groups, and communities. It may also be used to measure behavior change before and after transgender-specific educational and behavioral interventions.