Kernel Estimation of Rate Function for Recurrent Event Data

Abstract.  Recurrent event data are largely characterized by the rate function but smoothing techniques for estimating the rate function have never been rigorously developed or studied in statistical literature. This paper considers the moment and least squares methods for estimating the rate function from recurrent event data. With an independent censoring assumption on the recurrent event process, we study statistical properties of the proposed estimators and propose bootstrap procedures for the bandwidth selection and for the approximation of confidence intervals in the estimation of the occurrence rate function. It is identified that the moment method without resmoothing via a smaller bandwidth will produce a curve with nicks occurring at the censoring times, whereas there is no such problem with the least squares method. Furthermore, the asymptotic variance of the least squares estimator is shown to be smaller under regularity conditions. However, in the implementation of the bootstrap procedures, the moment method is computationally more efficient than the least squares method because the former approach uses condensed bootstrap data. The performance of the proposed procedures is studied through Monte Carlo simulations and an epidemiological example on intravenous drug users.     

A new two sample type-II progressive censoring scheme

In this paper we introduce a new type-II progressive censoring scheme for two samples. It is observed that the proposed censoring scheme is analytically more tractable than the existing joint progressive type-II censoring scheme proposed by Rasouli and Balakrishnan. The maximum likelihood estimators of the unknown parameters are obtained and their exact distributions are derived. Based on the exact distributions of the maximum likelihood estimators exact confidence intervals are also constructed. For comparison purposes we have used bootstrap confidence intervals also. One data analysis has been performed for illustrative purposes. Finally we propose some open problems.     

Bootstrap adaptive estimation: The trimmed-mean example

We consider the problem of choosing among a class of possible estimators by selecting the estimator with the smallest bootstrap estimate of finite sample variance. This is an alternative to using cross-validation to choose an estimator adaptively. The problem of a confidence interval based on such an adaptive estimator is considered. We illustrate the ideas by applying the method to the problem of choosing the trimming proportion of an adaptive trimmed mean. It is shown that a bootstrap adaptive trimmed mean is asymptotically normal with an asymptotic variance equal to the smallest among trimmed means. The asymptotic coverage probability of a bootstrap confidence interval based on such adaptive estimators is shown to have the nominal level. The intervals based on the asymptotic normality of the estimator share the same asymptotic result, but have poor small-sample properties compared to the bootstrap intervals. A small-sample simulation demonstrates that bootstrap adaptive trimmed means adapt themselves rather well even for samples of size 10.     

Efficient mean estimation in log-normal linear models

Log-normal linear models are widely used in applications, and many times it is of interest to predict the response variable or to estimate the mean of the response variable at the original scale for a new set of covariate values. In this paper we consider the problem of efficient estimation of the conditional mean of the response variable at the original scale for log-normal linear models. Several existing estimators are reviewed first, including the maximum likelihood (ML) estimator, the restricted ML (REML) estimator, the uniformly minimum variance unbiased (UMVU) estimator, and a bias-corrected REML estimator. We then propose two estimators that minimize the asymptotic mean squared error and the asymptotic bias, respectively. A parametric bootstrap procedure is also described to obtain confidence intervals for the proposed estimators. Both the new estimators and the bootstrap procedure are very easy to implement. Comparisons of the estimators using simulation studies suggest that our estimators perform better than the existing ones, and the bootstrap procedure yields confidence intervals with good coverage properties. A real application of estimating the mean sediment discharge is used to illustrate the methodology.     

Statistical analysis of competing risks model from Marshall–Olkin extended Chen distribution under adaptive progressively interval censoring with random removals

In this paper, a new censoring scheme named by adaptive progressively interval censoring scheme is introduced. The competing risks data come from Marshall–Olkin extended Chen distribution under the new censoring scheme with random removals. We obtain the maximum likelihood estimators of the unknown parameters and the reliability function by using the EM algorithm based on the failure data. In addition, the bootstrap percentile confidence intervals and bootstrap-t confidence intervals of the unknown parameters are obtained. To test the equality of the competing risks model, the likelihood ratio tests are performed. Then, Monte Carlo simulation is conducted to evaluate the performance of the estimators under different sample sizes and removal schemes. Finally, a real data set is analyzed for illustration purpose.     

Exact Likelihood Inference for Two Exponential Populations Under Joint Progressive Type-II Censoring

Comparative lifetime experiments are of great importance when the interest is in ascertaining the relative merits of two competing products with regard to their reliability. In this article, we consider two exponential populations and when joint progressive Type-II censoring is implemented on the two samples. We then derive the moment generating functions and the exact distributions of the maximum likelihood estimators (MLEs) of the mean lifetimes of the two exponential populations under such a joint progressive Type-II censoring. We then discuss the exact lower confidence bounds, exact confidence intervals, and simultaneous confidence regions. Next, we discuss the corresponding approximate results based on the asymptotic normality of the MLEs as well as those based on the Bayesian method. All these confidence intervals and regions are then compared by means of Monte Carlo simulations with those obtained from bootstrap methods. Finally, an illustrative example is presented in order to illustrate all the methods of inference discussed here.     

Generalized inverted exponential distribution under progressive first-failure censoring

This article deals with progressive first-failure censoring, which is a generalization of progressive censoring. We derive maximum likelihood estimators of the unknown parameters and reliability characteristics of generalized inverted exponential distribution using progressive first-failure censored samples. The asymptotic confidence intervals and coverage probabilities for the parameters are obtained based on the observed Fisher's information matrix. Bayes estimators of the parameters and reliability characteristics under squared error loss function are obtained using the Lindley approximation and importance sampling methods. Also, highest posterior density credible intervals for the parameters are computed using importance sampling procedure. A Monte Carlo simulation study is conducted to analyse the performance of the estimators derived in the article. A real data set is discussed for illustration purposes. Finally, an optimal censoring scheme has been suggested using different optimality criteria.     

Statistical inference for the extreme value distribution under adaptive Type-II progressive censoring schemes

Adaptive Type-II progressive censoring schemes have been shown to be useful in striking a balance between statistical estimation efficiency and the time spent on a life-testing experiment. In this article, some general statistical properties of an adaptive Type-II progressive censoring scheme are first investigated. A bias correction procedure is proposed to reduce the bias of the maximum likelihood estimators (MLEs). We then focus on the extreme value distributed lifetimes and derive the Fisher information matrix for the MLEs based on these properties. Four different approaches are proposed to construct confidence intervals for the parameters of the extreme value distribution. Performance of these methods is compared through an extensive Monte Carlo simulation.     

Parameter Estimation of Type-II Hybrid Censored Weighted Exponential Distribution

A hybrid censoring scheme is a mixture of Type-I and Type-II censoring schemes. We study the estimation of parameters of weighted exponential distribution based on Type-II hybrid censored data. By applying the EM algorithm, maximum likelihood estimators are evaluated. Using Fisher information matrix, asymptotic confidence intervals are provided. By applying Markov chain Monte Carlo techniques, Bayes estimators, and corresponding highest posterior density confidence intervals of parameters are obtained. Monte Carlo simulations are performed to compare the performances of the different methods, and one dataset is analyzed for illustrative purposes.     

Estimating kurtosis and confidence intervals for the variance under nonnormality

Exact confidence intervals for variances rely on normal distribution assumptions. Alternatively, large-sample confidence intervals for the variance can be attained if one estimates the kurtosis of the underlying distribution. The method used to estimate the kurtosis has a direct impact on the performance of the interval and thus the quality of statistical inferences. In this paper the author considers a number of kurtosis estimators combined with large-sample theory to construct approximate confidence intervals for the variance. In addition, a nonparametric bootstrap resampling procedure is used to build bootstrap confidence intervals for the variance. Simulated coverage probabilities using different confidence interval methods are computed for a variety of sample sizes and distributions. A modification to a conventional estimator of the kurtosis, in conjunction with adjustments to the mean and variance of the asymptotic distribution of a function of the sample variance, improves the resulting coverage values for leptokurtically distributed populations.     

Exact inference for competing risks model with generalized type-I hybrid censored exponential data

Recently, exact inference under hybrid censoring scheme has attracted extensive attention in the field of reliability analysis. However, most of the authors neglect the possibility of competing risks model. This paper mainly discusses the exact likelihood inference for the analysis of generalized type-I hybrid censoring data with exponential competing failure model. Based on the maximum likelihood estimates for unknown parameters, we establish the exact conditional distribution of parameters by conditional moment generating function, and then obtain moment properties as well as exact confidence intervals (CIs) for parameters. Furthermore, approximate CIs are constructed by asymptotic distribution and bootstrap method as well. We also compare their performances with exact method through the use of Monte Carlo simulations. And finally, a real data set is analysed to illustrate the validity of all the methods developed here.     

Confidence Intervals for Reliability of Stress-Strength Models in the Normal Case

In this article, we propose some procedures to get confidence intervals for the reliability in stress-strength models. The confidence intervals are obtained either through a parametric bootstrap procedure or using asymptotic results, and are applied to the particular context of two independent normal random variables. The performance of these estimators and other known approximate estimators are empirically checked through a simulation study which considers several scenarios.     

Some Further Issues Concerning Likelihood Inference for Left Truncated and Right Censored Lognormal Data

The maximum likelihood estimates (MLEs) of the parameters of a two-parameter lognormal distribution with left truncation and right censoring are developed through the Expectation Maximization (EM) algorithm. For comparative purpose, the MLEs are also obtained by the Newton–Raphson method. The asymptotic variance-covariance matrix of the MLEs is obtained by using the missing information principle, under the EM framework. Then, using asymptotic normality of the MLEs, asymptotic confidence intervals for the parameters are constructed. Asymptotic confidence intervals are also obtained using the estimated variance of the MLEs by the observed information matrix, and by using parametric bootstrap technique. Different confidence intervals are then compared in terms of coverage probabilities, through a Monte Carlo simulation study. A prediction problem concerning the future lifetime of a right censored unit is also considered. A numerical example is given to illustrate all the inferential methods developed here.     

Inference on a progressive type I interval-censored truncated normal distribution

In this paper, we consider the problem of making statistical inference for a truncated normal distribution under progressive type I interval censoring. We obtain maximum likelihood estimators of unknown parameters using the expectation-maximization algorithm and in sequel, we also compute corresponding midpoint estimates of parameters. Estimation based on the probability plot method is also considered. Asymptotic confidence intervals of unknown parameters are constructed based on the observed Fisher information matrix. We obtain Bayes estimators of parameters with respect to informative and non-informative prior distributions under squared error and linex loss functions. We compute these estimates using the importance sampling procedure. The highest posterior density intervals of unknown parameters are constructed as well. We present a Monte Carlo simulation study to compare the performance of proposed point and interval estimators. Analysis of a real data set is also performed for illustration purposes. Finally, inspection times and optimal censoring plans based on the expected Fisher information matrix are discussed.     

On hybrid censored Weibull distribution

A hybrid censoring is a mixture of Type-I and Type-II censoring schemes. This article presents the statistical inferences on Weibull parameters when the data are hybrid censored. The maximum likelihood estimators (MLEs) and the approximate maximum likelihood estimators are developed for estimating the unknown parameters. Asymptotic distributions of the MLEs are used to construct approximate confidence intervals. Bayes estimates and the corresponding highest posterior density credible intervals of the unknown parameters are obtained under suitable priors on the unknown parameters and using the Gibbs sampling procedure. The method of obtaining the optimum censoring scheme based on the maximum information measure is also developed. Monte Carlo simulations are performed to compare the performances of the different methods and one data set is analyzed for illustrative purposes.     

Analysis of Type-II hybrid censored competing risks data

Kundu and Gupta [Analysis of hybrid life-tests in presence of competing risks. Metrica. 2007;65:159–170] provided the analysis of Type-I hybrid censored competing risks data, when the lifetime distributions of the competing cause of failures follows exponential distribution. In this paper, we consider the analysis of Type-II hybrid censored competing risks data. It is assumed that latent lifetime distributions of the competing causes of failures follow independent exponential distributions with different scale parameters. It is observed that the maximum likelihood estimators of the unknown parameters do not always exist. We propose the modified estimators of the scale parameters, which coincide with the corresponding maximum likelihood estimators when they exist, and asymptotically they are equivalent. We obtain the exact distribution of the proposed estimators. Using the exact distributions of the proposed estimators, associated confidence intervals are obtained. The asymptotic and bootstrap confidence intervals of the unknown parameters are also provided. Further, Bayesian inference of some unknown parametric functions under a very flexible Beta-Gamma prior is considered. Bayes estimators and associated credible intervals of the unknown parameters are obtained using the Monte Carlo method. Extensive Monte Carlo simulations are performed to see the effectiveness of the proposed estimators and one real data set has been analysed for the illustrative purposes. It is observed that the proposed model and the method work quite well for this data set.     

Non‐parametric Copula Estimation Under Bivariate Censoring

In this paper, we consider non‐parametric copula inference under bivariate censoring. Based on an estimator of the joint cumulative distribution function, we define a discrete and two smooth estimators of the copula. The construction that we propose is valid for a large range of estimators of the distribution function and therefore for a large range of bivariate censoring frameworks. Under some conditions on the tails of the distributions, the weak convergence of the corresponding copula processes is obtained in l^∞([0,1]²). We derive the uniform convergence rates of the copula density estimators deduced from our smooth copula estimators. Investigation of the practical behaviour of these estimators is performed through a simulation study and two real data applications, corresponding to different censoring settings. We use our non‐parametric estimators to define a goodness‐of‐fit procedure for parametric copula models. A new bootstrap scheme is proposed to compute the critical values.     

Bayesian inference using product of spacings function for Progressive hybrid Type-I censoring scheme

This article is devoted to the development of product of spacings estimator for a Progressive hybrid Type-I censoring scheme with binomial removals. The experimental units are assumed to follow inverse Lindley distribution. We propose a Bayes estimator of associated scale parameter based on the product of spacings function and simultaneously compare it with that obtained under a usual Bayesian estimation procedure. The estimators are obtained under the squared error loss function along with corresponding HP intervals evaluated by using the Markov chain Monte-Carlo technique. The classical product of spacings estimator has also been derived and compared with the maximum likelihood estimator in addition to 95% average asymptotic confidence intervals. The applicability of the proposed methods is demonstrated by analysing a real data of guinea pigs affected with tuberculosis for the considered censoring scheme.     

On progressively censored inverted exponentiated Rayleigh distribution

In this paper, we discuss a progressively censored inverted exponentiated Rayleigh distribution. Estimation of unknown parameters is considered under progressive censoring using maximum likelihood and Bayesian approaches. Bayes estimators of unknown parameters are derived with respect to different symmetric and asymmetric loss functions using gamma prior distributions. An importance sampling procedure is taken into consideration for deriving these estimates. Further highest posterior density intervals for unknown parameters are constructed and for comparison purposes bootstrap intervals are also obtained. Prediction of future observations is studied in one- and two-sample situations from classical and Bayesian viewpoint. We further establish optimum censoring schemes using Bayesian approach. Finally, we conduct a simulation study to compare the performance of proposed methods and analyse two real data sets for illustration purposes.     

Bayesian estimation based on progressive Type-II censoring from two-parameter bathtub-shaped lifetime model: an Markov chain Monte Carlo approach

In this paper, maximum likelihood and Bayes estimators of the parameters, reliability and hazard functions have been obtained for two-parameter bathtub-shaped lifetime distribution when sample is available from progressive Type-II censoring scheme. The Markov chain Monte Carlo (MCMC) method is used to compute the Bayes estimates of the model parameters. It has been assumed that the parameters have gamma priors and they are independently distributed. Gibbs within the Metropolis–Hasting algorithm has been applied to generate MCMC samples from the posterior density function. Based on the generated samples, the Bayes estimates and highest posterior density credible intervals of the unknown parameters as well as reliability and hazard functions have been computed. The results of Bayes estimators are obtained under both the balanced-squared error loss and balanced linear-exponential (BLINEX) loss. Moreover, based on the asymptotic normality of the maximum likelihood estimators the approximate confidence intervals (CIs) are obtained. In order to construct the asymptotic CI of the reliability and hazard functions, we need to find the variance of them, which are approximated by delta and Bootstrap methods. Two real data sets have been analyzed to demonstrate how the proposed methods can be used in practice.