An Inverse‐regression Method of Dependent Variable Transformation for Dimension Reduction with Non‐linear Confounding

Many model‐free dimension reduction methods have been developed for high‐dimensional regression data but have not paid much attention on problems with non‐linear confounding. In this paper, we propose an inverse‐regression method of dependent variable transformation for detecting the presence of non‐linear confounding. The benefit of using geometrical information from our method is highlighted. A ratio estimation strategy is incorporated in our approach to enhance the interpretation of variable selection. This approach can be implemented not only in principal Hessian directions (PHD) but also in other recently developed dimension reduction methods. Several simulation examples that are reported for illustration and comparisons are made with sliced inverse regression and PHD in ignorance of non‐linear confounding. An illustrative application to one real data is also presented.     

An approximation of logarithmic functions in the regression setting

We consider a method of moments approach for dealing with censoring at zero for data expressed in levels when researchers would like to take logarithms. A Box–Cox transformation is employed. We explore this approach in the context of linear regression where both dependent and independent variables are censored. We contrast this method to two others, (1) dropping records of data containing censored values and (2) assuming normality for censored observations and the residuals in the model. Across the methods considered, where researchers are interested primarily in the slope parameter, estimation bias is consistently reduced using the method of moments approach.     

Bayesian Conditional Mean Estimation in Log‐Normal Linear Regression Models with Finite Quadratic Expected Loss

Log‐normal linear regression models are popular in many fields of research. Bayesian estimation of the conditional mean of the dependent variable is problematic as many choices of the prior for the variance (on the log‐scale) lead to posterior distributions with no finite moments. We propose a generalized inverse Gaussian prior for this variance and derive the conditions on the prior parameters that yield posterior distributions of the conditional mean of the dependent variable with finite moments up to a pre‐specified order. The conditions depend on one of the three parameters of the suggested prior; the other two have an influence on inferences for small and medium sample sizes. A second goal of this paper is to discuss how to choose these parameters according to different criteria including the optimization of frequentist properties of posterior means.     

Two-stage informative cluster sampling—estimation and prediction with applications for small-area models

This paper considers the effects of informative two-stage cluster sampling on estimation and prediction. The aims of this article are twofold: first to estimate the parameters of the superpopulation model for two-stage cluster sampling from a finite population, when the sampling design for both stages is informative, using maximum likelihood estimation methods based on the sample-likelihood function; secondly to predict the finite population total and to predict the cluster-specific effects and the cluster totals for clusters in the sample and for clusters not in the sample. To achieve this we derive the sample and sample-complement distributions and the moments of the first and second stage measurements. Also we derive the conditional sample and conditional sample-complement distributions and the moments of the cluster-specific effects given the cluster measurements. It should be noted that classical design-based inference that consists of weighting the sample observations by the inverse of sample selection probabilities cannot be applied for the prediction of the cluster-specific effects for clusters not in the sample. Also we give an alternative justification of the Royall [1976. The linear least squares prediction approach to two-stage sampling. Journal of the American Statistical Association 71, 657–664] predictor of the finite population total under two-stage cluster population. Furthermore, small-area models are studied under informative sampling.     

Sliced inverse moment regression using weighted chi-squared tests for dimension reduction

We propose a new method for dimension reduction in regression using the first two inverse moments. We develop corresponding weighted chi-squared tests for the dimension of the regression. The proposed method considers linear combinations of sliced inverse regression (SIR) and the method using a new candidate matrix which is designed to recover the entire inverse second moment subspace. The optimal combination may be selected based on the p-values derived from the dimension tests. Theoretically, the proposed method, as well as sliced average variance estimate (SAVE), is more capable of recovering the complete central dimension reduction subspace than SIR and principle Hessian directions (pHd). Therefore it can substitute for SIR, pHd, SAVE, or any linear combination of them at a theoretical level. Simulation study indicates that the proposed method may have consistently greater power than SIR, pHd, and SAVE.     

Using Weight Functions in Spatial Point Pattern Analysis with Application to Plant Ecology Data

This paper presents procedures for percentile estimation in the three-parameter inverse Gaussian (IG3) and the two-parameter inverse Gaussian (IG2) distributions. All procedures require first the estimation of distribution parameters and second the computation of the desired quantile at the estimated parameters. Parameter estimation is accomplished by maximum likelihood (ML) or a mixed moments (MXM) method. A Newton-Rahpson (NR) procedure is used for inverting the CDF. Simulation and asymptotic results are given for the resulting estimators. Two sets of real data are used to illustrate the procedures.     

A Semiparametric Estimation Approach for Linear Mixed Models

Maximum likelihood approach is the most frequently employed approach for the inference of linear mixed models. However, it relies on the normal distributional assumption of the random effects and the within-subject errors, and it is lack of robustness against outliers. This article proposes a semiparametric estimation approach for linear mixed models. This approach is based on the first two marginal moments of the response variable, and does not require any parametric distributional assumptions of random effects or error terms. The consistency and asymptotically normality of the estimator are derived under fairly general conditions. In addition, we show that the proposed estimator has a bounded influence function and a redescending property so it is robust to outliers. The methodology is illustrated through an application to the famed Framingham cholesterol data. The finite sample behavior and the robustness properties of the proposed estimator are evaluated through extensive simulation studies.     

Analysis of longitudinal multiple-source binary data using generalized estimating equations

Summary.  We present a multivariate logistic regression model for the joint analysis of longitudinal multiple-source binary data. Longitudinal multiple-source binary data arise when repeated binary measurements are obtained from two or more sources, with each source providing a measure of the same underlying variable. Since the number of responses on each subject is relatively large, the empirical variance estimator performs poorly and cannot be relied on in this setting. Two methods for obtaining a parsimonious within-subject association structure are considered. An additional complication arises with estimation, since maximum likelihood estimation may not be feasible without making unrealistically strong assumptions about third- and higher order moments. To circumvent this, we propose the use of a generalized estimating equations approach. Finally, we present an analysis of multiple-informant data obtained longitudinally from a psychiatric interventional trial that motivated the model developed in the paper.     

Local Linear Estimation of Recurrent Jump—Diffusion Models

In this article, we provide a nonparametric estimation of first and second infinitesimal moments of the underlying jump diffusion model. We show that under certain regularity conditions the nonparametric estimations of first and second infinitesimal moments based on the local linear estimator are consistent and asymptotically follow normal distributions.     

Robust Bayesian analysis of the binomial empirical Bayes problem

Empirical Bayes estimation is considered for an i.i.d. sequence of binomial parameters θ_i arising from an unknown prior distribution G(.). This problem typically arises in industrial sampling, where samples from lots are routinely used to estimate the lot fraction defective of each lot. Two related issues are explored. The first concerns the fact that only the first few moments of G are typically estimable from the data. This suggests consideration of the interval of estimates (e.g., posterior means) corresponding to the different possible G with the specified moments. Such intervals can be obtained by application of well-known moment theory. The second development concerns the need to acknowledge the uncertainty in the estimation of the first few moments of G. Our proposal is to determine a credible set for the moments, and then find the range of estimates (e.g., posterior means) corresponding to the different possible G with moments in the credible set.     

On negative moments of generalized poisson distribution

The negative moments have been used in estimation theory and life testing problems. In this paper we obtain the first inverse moment of a decapitated generalized Poisson distribution of Consul and Jain (1973) and exhibit an application in the estimation of soil micro-organisms.     

Estimating the parameters of a BINMA Poisson model for a non-stationary bivariate time series

This article proposes a novel non-stationary BINMA time series model by extending two INMA processes where their innovation series follow the bivariate Poisson under time-varying moment assumptions. This article also demonstrates, through simulation studies, the use and superiority of the generalized quasi-likelihood (GQL) approach to estimate the regression effects, which is computationally less complicated as compared to conditional maximum likelihood estimation (CMLE) and the feasible generalized least squares (FGLS). The serial and bivariate dependence correlations are estimated by a robust method of moments.     

Count Data Models with Correlated Unobserved Heterogeneity

Abstract. As previously argued, the correlation between included and omitted regressors generally causes inconsistency of standard estimators for count data models. Non‐linear instrumental variables estimation of an exponential model under conditional moment restrictions is one of the proposed remedies. This approach is extended here by fully exploiting the model assumptions and thereby improving efficiency of the resulting estimator. Empirical likelihood in particular has favourable properties in this setting compared with the two‐step generalized method of moments, as demonstrated in a Monte Carlo experiment. The proposed method is applied to the estimation of a cigarette demand function.     

A recursive approach to parameter estimation in regression and time series models

In this paper we discuss the recursive (or on line) estimation in (i) regression and (ii) autoregressive integrated moving average (ARIMA) time series models. The adopted approach uses Kalman filtering techniques to calculate estimates recursively. This approach is used for the estimation of constant as well as time varying parameters. In the first section of the paper we consider the linear regression model. We discuss recursive estimation both for constant and time varying parameters. For constant parameters, Kalman filtering specializes to recursive least squares. In general, we allow the parameters to vary according to an autoregressive integrated moving average process and update the parameter estimates recursively. Since the stochastic model for the parameter changes will "be rarely known, simplifying assumptions have to be made. In particular we assume a random walk model for the time varying parameters and show how to determine whether the parameters are changing over time. This is illustrated with an example.     

Estimating the structural dimension of regressions via parametric inverse regression

A new estimation method for the dimension of a regression at the outset of an analysis is proposed. A linear subspace spanned by projections of the regressor vector X , which contains part or all of the modelling information for the regression of a vector Y on X , and its dimension are estimated via the means of parametric inverse regression. Smooth parametric curves are fitted to the p inverse regressions via a multivariate linear model. No restrictions are placed on the distribution of the regressors. The estimate of the dimension of the regression is based on optimal estimation procedures. A simulation study shows the method to be more powerful than sliced inverse regression in some situations.     

An effective approach to linear calibration estimation with its applications

Abstract

The availability of some extra information, along with the actual variable of interest, may be easily accessible in different practical situations. A sensible use of the additional source may help to improve the properties of statistical techniques. In this study, we focus on the estimators for calibration and intend to propose a setup where we reply only on first two moments instead of modeling the whole distributional shape. We have proposed an estimator for linear calibration problems and investigated it under normal and skewed environments. We have partitioned its mean squared error into intrinsic and estimation components. We have observed that the bias and mean squared error of the proposed estimator are function of four dimensionless quantities. It is to be noticed that both the classical and the inverse estimators become the special cases of the proposed estimator. Moreover, the mean squared error of the proposed estimator and the exact mean squared error of the inverse estimator coincide. We have also observed that the proposed estimator performs quite well for skewed errors as well. The real data applications are also included in the study for practical considerations.     

On familial Poisson mixed models with multi-dimensional random effects

When a generalized linear mixed model with multiple (two or more) sources of random effects is considered, the inferences may vary depending on the nature of the random effects. In this paper, we consider a familial Poisson mixed model where each of the count responses of a family are influenced by two independent unobservable familial random effects with two distinct components of dispersion. A generalized quasilikelihood (GQL) approach is discussed for the estimation of the dispersion components as well as the regression effects of the model. A simulation study is conducted to examine the relative performance of the GQL approach as opposed to a simpler method of moments. Furthermore, the GQL estimation methodology is illustrated by using health care utilization data that follow a Poisson mixed model with one component of dispersion and by using simulated asthma data that follow a Poisson mixed model with two sources of random effects with two distinct components of dispersion.     

Nonparametric bayesian inference for dichotomous response models

A Bayesian least squares approach is taken here to estimate certain parameters in generalized linear models for dichotomous response data. The method requires that only first and second moments of the probability distribution representing prior information be specified* Examples are presented to illustrate situations having direct estimates as well as those which require approximate or iterative solutions.     

Proportional hazards regression with interval-censored and left-truncated data

This paper considers the estimation of the regression coefficients in the Cox proportional hazards model with left-truncated and interval-censored data. Using the approaches of Pan [A multiple imputation approach to Cox regression with interval-censored data, Biometrics 56 (2000), pp. 199–203] and Heller [Proportional hazards regression with interval censored data using an inverse probability weight, Lifetime Data Anal. 17 (2011), pp. 373–385], we propose two estimates of the regression coefficients. The first estimate is based on a multiple imputation methodology. The second estimate uses an inverse probability weight to select event time pairs where the ordering is unambiguous. A simulation study is conducted to investigate the performance of the proposed estimators. The proposed methods are illustrated using the Centers for Disease Control and Prevention (CDC) acquired immunodeficiency syndrome (AIDS) Blood Transfusion Data.     

Least Squares Consistent Estimates for Arbitrary Regression Functions Over an Abstract Space

In this article, we propose a new approach to sieve estimation for a general regression function when the dimension of the finite dimensional subspaces is a random quantity depending on the values of the observations.

The technique is introduced with the help of a simulation study on a functional linear model under extremely mild assumptions.

A sketch of the proof concerning the main statements is then given in the more general case when the regression function is not necessarily linear.