A Profile Conditional Likelihood Approach for the Semiparametric Transformation Regression Model with Missing Covariates

We propose a profile conditional likelihood approach to handle missing covariates in the general semiparametric transformation regression model. The method estimates the marginal survival function by the Kaplan-Meier estimator, and then estimates the parameters of the survival model and the covariate distribution from a conditional likelihood, substituting the Kaplan-Meier estimator for the marginal survival function in the conditional likelihood. This method is simpler than full maximum likelihood approaches, and yields consistent and asymptotically normally distributed estimator of the regression parameter when censoring is independent of the covariates. The estimator demonstrates very high relative efficiency in simulations. When compared with complete-case analysis, the proposed estimator can be more efficient when the missing data are missing completely at random and can correct bias when the missing data are missing at random. The potential application of the proposed method to the generalized probit model with missing continuous covariates is also outlined.     

Exact likelihood inference for two exponential populations based on a joint generalized Type-I hybrid censored sample

Following the work of Chen and Bhattacharyya [Exact confidence bounds for an exponential parameter under hybrid censoring. Comm Statist Theory Methods. 1988;17:1857–1870], several results have been developed regarding the exact likelihood inference of exponential parameters based on different forms of censored samples. In this paper, the conditional maximum likelihood estimators (MLEs) of two exponential mean parameters are derived under joint generalized Type-I hybrid censoring on the two samples. The moment generating functions (MGFs) and the exact densities of the conditional MLEs are obtained, using which exact confidence intervals are then developed for the model parameters. We also derive the means, variances, and mean squared errors of these estimates. An efficient computational method is developed based on the joint MGF. Finally, an example is presented to illustrate the methods of inference developed here.     

Generalized inverted exponential distribution under hybrid censoring

The hybrid censoring scheme is a mixture of Type-I and Type-II censoring schemes. Based on hybrid censored samples, we first derive the maximum likelihood estimators of the unknown parameters and the expected Fisher’s information matrix of the generalized inverted exponential distribution (GIED). Monte Carlo simulations are performed to study the performance of the maximum likelihood estimators. Next we consider Bayes estimation under the squared error loss function. These Bayes estimates are evaluated by applying Lindley’s approximation method, the importance sampling procedure and Metropolis–Hastings algorithm. The importance sampling technique is used to compute the highest posterior density credible intervals. Two data sets are analyzed for illustrative purposes. Finally, we discuss a method of obtaining the optimum hybrid censoring scheme.     

On estimating parameters of a progressively censored lognormal distribution

We consider the problem of making statistical inference on unknown parameters of a lognormal distribution under the assumption that samples are progressively censored. The maximum likelihood estimates (MLEs) are obtained by using the expectation-maximization algorithm. The observed and expected Fisher information matrices are provided as well. Approximate MLEs of unknown parameters are also obtained. Bayes and generalized estimates are derived under squared error loss function. We compute these estimates using Lindley's method as well as importance sampling method. Highest posterior density interval and asymptotic interval estimates are constructed for unknown parameters. A simulation study is conducted to compare proposed estimates. Further, a data set is analysed for illustrative purposes. Finally, optimal progressive censoring plans are discussed under different optimality criteria and results are presented.     

Exact inference for competing risks model with generalized type-I hybrid censored exponential data

Recently, exact inference under hybrid censoring scheme has attracted extensive attention in the field of reliability analysis. However, most of the authors neglect the possibility of competing risks model. This paper mainly discusses the exact likelihood inference for the analysis of generalized type-I hybrid censoring data with exponential competing failure model. Based on the maximum likelihood estimates for unknown parameters, we establish the exact conditional distribution of parameters by conditional moment generating function, and then obtain moment properties as well as exact confidence intervals (CIs) for parameters. Furthermore, approximate CIs are constructed by asymptotic distribution and bootstrap method as well. We also compare their performances with exact method through the use of Monte Carlo simulations. And finally, a real data set is analysed to illustrate the validity of all the methods developed here.     

Inference and optimal design of multiple constant-stress testing for generalized half-normal distribution under type-II progressive censoring

The generalized half-normal (GHN) distribution and progressive type-II censoring are considered in this article for studying some statistical inferences of constant-stress accelerated life testing. The EM algorithm is considered to calculate the maximum likelihood estimates. Fisher information matrix is formed depending on the missing information law and it is utilized for structuring the asymptomatic confidence intervals. Further, interval estimation is discussed through bootstrap intervals. The Tierney and Kadane method, importance sampling procedure and Metropolis-Hastings algorithm are utilized to compute Bayesian estimates. Furthermore, predictive estimates for censored data and the related prediction intervals are obtained. We consider three optimality criteria to find out the optimal stress level. A real data set is used to illustrate the importance of GHN distribution as an alternative lifetime model for well-known distributions. Finally, a simulation study is provided with discussion.     

Statistical analysis for competing risks model from a Weibull distribution under progressively hybrid censoring

This paper considers the statistical analysis for competing risks model under the Type-I progressively hybrid censoring from a Weibull distribution. We derive the maximum likelihood estimates and the approximate maximum likelihood estimates of the unknown parameters. We then use the bootstrap method to construct the confidence intervals. Based on the non informative prior, a sampling algorithm using the acceptance–rejection sampling method is presented to obtain the Bayes estimates, and Monte Carlo method is employed to construct the highest posterior density credible intervals. The simulation results are provided to show the effectiveness of all the methods discussed here and one data set is analyzed.     

Approximate MLE for the scale parameter of the generalized exponential distribution under random censoring

In this paper, we consider the maximum likelihood estimator (MLE) of the scale parameter of the generalized exponential (GE) distribution based on a random censoring model. We assume the censoring distribution also follows a GE distribution. Since the estimator does not provide an explicit solution, we propose a simple method of deriving an explicit estimator by approximating the likelihood function. In order to compare the performance of the estimators, Monte Carlo simulation is conducted. The results show that the MLE and the approximate MLE are almost identical in terms of bias and variance.     

Comparisons of methods of estimation for a pareto distribution of the first kind

This paper compares methods of estimation for the parameters of a Pareto distribution of the first kind to determine which method provides the better estimates when the observations are censored, The unweighted least squares (LS) and the maximum likelihood estimates (MLE) are presented for both censored and uncensored data. The MLE's are obtained using two methods, In the first, called the ML method, it is shown that log-likelihood is maximized when the scale parameter is the minimum sample value. In the second method, called the modified ML (MML) method, the estimates are found by utilizing the maximum likelihood value of the shape parameter in terms of the scale parameter and the equation for the mean of the first order statistic as a function of both parameters. Since censored data often occur in applications, we study two types of censoring for their effects on the methods of estimation: Type II censoring and multiple random censoring. In this study we consider different sample sizes and several values of the true shape and scale parameters.

Comparisons are made in terms of bias and the mean squared error of the estimates. We propose that the LS method be generally preferred over the ML and MML methods for estimating the Pareto parameter γ for all sample sizes, all values of the parameter and for both complete and censored samples. In many cases, however, the ML estimates are comparable in their efficiency, so that either estimator can effectively be used. For estimating the parameter α, the LS method is also generally preferred for smaller values of the parameter (α ≤4). For the larger values of the parameter, and for censored samples, the MML method appears superior to the other methods with a slight advantage over the LS method. For larger values of the parameter α, for censored samples and all methods, underestimation can be a problem.     

On hybrid censored Weibull distribution

A hybrid censoring is a mixture of Type-I and Type-II censoring schemes. This article presents the statistical inferences on Weibull parameters when the data are hybrid censored. The maximum likelihood estimators (MLEs) and the approximate maximum likelihood estimators are developed for estimating the unknown parameters. Asymptotic distributions of the MLEs are used to construct approximate confidence intervals. Bayes estimates and the corresponding highest posterior density credible intervals of the unknown parameters are obtained under suitable priors on the unknown parameters and using the Gibbs sampling procedure. The method of obtaining the optimum censoring scheme based on the maximum information measure is also developed. Monte Carlo simulations are performed to compare the performances of the different methods and one data set is analyzed for illustrative purposes.     

Bayes Inference in Constant Partially Accelerated Life Tests for the Generalized Exponential Distribution with Progressive Censoring

In this paper, the problem of constant partially accelerated life tests when the lifetime follows the generalized exponential distribution is considered. Based on progressive type-II censoring scheme, the maximum likelihood and Bayes methods of estimation are used for estimating the distribution parameters and acceleration factor. A Monte Carlo simulation study is carried out to examine the performance of the obtained estimates.     

Estimation using hybrid censored data from a generalized inverted exponential distribution

ABSTRACT

We consider point and interval estimation of the unknown parameters of a generalized inverted exponential distribution in the presence of hybrid censoring. The maximum likelihood estimates are obtained using EM algorithm. We then compute Fisher information matrix using the missing value principle. Bayes estimates are derived under squared error and general entropy loss functions. Furthermore, approximate Bayes estimates are obtained using Tierney and Kadane method as well as using importance sampling approach. Asymptotic and highest posterior density intervals are also constructed. Proposed estimates are compared numerically using Monte Carlo simulations and a real data set is analyzed for illustrative purposes.     

Efficiency estimation of type-I censored sample from the Weibull distribution based on sup-entropy

On the basis of Awad sup-entropy, the efficiency function for type-I censored sample from the Weibull distribution is numerically introduced. The properties of the derived efficiency are discussed. Furthermore, for a given efficiency, the termination time of the experiment, and the maximum likelihood estimates for the Weibull parameters, are proposed. Simulation results are tabulated and discussed. Censored and complete samples are compared for a wide range of the efficiency. The comparisons show the quality of the developed algorithms and the effectiveness of using censoring in estimating with the Weibull distribution.     

Estimation for Location-Scale Models with Censored Data

This article considers a class of estimators for the location and scale parameters in the location-scale model based on ‘synthetic data’ when the observations are randomly censored on the right. The asymptotic normality of the estimators is established using counting process and martingale techniques when the censoring distribution is known and unknown, respectively. In the case when the censoring distribution is known, we show that the asymptotic variances of this class of estimators depend on the data transformation and have a lower bound which is not achievable by this class of estimators. However, in the case that the censoring distribution is unknown and estimated by the Kaplan–Meier estimator, this class of estimators has the same asymptotic variance and attains the lower bound for variance for the case of known censoring distribution. This is different from censored regression analysis, where asymptotic variances depend on the data transformation. Our method has three valuable advantages over the method of maximum likelihood estimation. First, our estimators are available in a closed form and do not require an iterative algorithm. Second, simulation studies show that our estimators being moment-based are comparable to maximum likelihood estimators and outperform them when sample size is small and censoring rate is high. Third, our estimators are more robust to model misspecification than maximum likelihood estimators. Therefore, our method can serve as a competitive alternative to the method of maximum likelihood in estimation for location-scale models with censored data. A numerical example is presented to illustrate the proposed method.     

Optimal experimental plan for multi-level stress testing with Weibull regression under progressive Type-II extremal censoring

In the design of constant-stress life-testing experiments, the optimal allocation in a multi-level stress test with Type-I or Type-II censoring based on the Weibull regression model has been studied in the literature. Conventional Type-I and Type-II censoring schemes restrict our ability to observe extreme failures in the experiment and these extreme failures are important in the estimation of upper quantiles and understanding of the tail behaviors of the lifetime distribution. For this reason, we propose the use of progressive extremal censoring at each stress level, whereas the conventional Type-II censoring is a special case. The proposed experimental scheme allows some extreme failures to be observed. The maximum likelihood estimators of the model parameters, the Fisher information, and asymptotic variance–covariance matrices of the maximum likelihood estimates are derived. We consider the optimal experimental planning problem by looking at four different optimality criteria. To avoid the computational burden in searching for the optimal allocation, a simple search procedure is suggested. Optimal allocation of units for two- and four-stress-level situations is determined numerically. The asymptotic Fisher information matrix and the asymptotic optimal allocation problem are also studied and the results are compared with optimal allocations with specified sample sizes. Finally, conclusions and some practical recommendations are provided.     

Robust methods for generalized linear models with nonignorable missing covariates

The EM algorithm is often used for finding the maximum likelihood estimates in generalized linear models with incomplete data. In this article, the author presents a robust method in the framework of the maximum likelihood estimation for fitting generalized linear models when nonignorable covariates are missing. His robust approach is useful for downweighting any influential observations when estimating the model parameters. To avoid computational problems involving irreducibly high‐dimensional integrals, he adopts a Metropolis‐Hastings algorithm based on a Markov chain sampling method. He carries out simulations to investigate the behaviour of the robust estimates in the presence of outliers and missing covariates; furthermore, he compares these estimates to the classical maximum likelihood estimates. Finally, he illustrates his approach using data on the occurrence of delirium in patients operated on for abdominal aortic aneurysm.     

Bayes estimation of Gompertz distribution parameters and acceleration factor under partially accelerated life tests with type-I censoring

In this paper, the Bayesian approach is applied to the estimation problem in the case of step stress partially accelerated life tests with two stress levels and type-I censoring. Gompertz distribution is considered as a lifetime model. The posterior means and posterior variances are derived using the squared-error loss function. The Bayes estimates cannot be obtained in explicit forms. Approximate Bayes estimates are computed using the method of Lindley [D.V. Lindley, Approximate Bayesian methods, Trabajos Estadistica 31 (1980), pp. 223–237]. The advantage of this proposed method is shown. The approximate Bayes estimates obtained under the assumption of non-informative priors are compared with their maximum likelihood counterparts using Monte Carlo simulation.     

Statistical Inference of Type-II Progressively Hybrid Censored Data with Weibull Lifetimes

In this article, we discuss the maximum likelihood estimators and approximate maximum likelihood estimators of the parameters of the Weibull distribution with two different progressively hybrid censoring schemes. We also present the associated expressions of the expected total test time and the expected effective sample size which will be useful for experimental planning purpose. Finally, the efficiency of the point estimation of the parameters based on the two progressive hybrid censoring schemes are compared and the merits of each censoring scheme are discussed.     

Generalized Empirical Likelihood Inference in Generalized Linear Models for Longitudinal Data

In this article, the generalized linear model for longitudinal data is studied. A generalized empirical likelihood method is proposed by combining generalized estimating equations and quadratic inference functions based on the working correlation matrix. It is proved that the proposed generalized empirical likelihood ratios are asymptotically chi-squared under some suitable conditions, and hence it can be used to construct the confidence regions of the parameters. In addition, the maximum empirical likelihood estimates of parameters are obtained, and their asymptotic normalities are proved. Some simulations are undertaken to compare the generalized empirical likelihood and normal approximation-based method in terms of coverage accuracies and average areas/lengths of confidence regions/intervals. An example of a real data is used for illustrating our methods.