Empirical Likelihood for Censored Linear Regression

In this paper we investigate the empirical likelihood method in a linear regression model when the observations are subject to random censoring. An empirical likelihood ratio for the slope parameter vector is defined and it is shown that its limiting distribution is a weighted sum of independent chi-square distributions. This reduces to the empirical likelihood to the linear regression model first studied by Owen (1991) if there is no censoring present. Some simulation studies are presented to compare the empirical likelihood method with the normal approximation based method proposed in Lai et al. (1995). It was found that the empirical likelihood method performs much better than the normal approximation method.     

Empirical Likelihood Local Polynomial Regression Analysis of Clustered Data

Abstract. In this article, a naive empirical likelihood ratio is constructed for a non‐parametric regression model with clustered data, by combining the empirical likelihood method and local polynomial fitting. The maximum empirical likelihood estimates for the regression functions and their derivatives are obtained. The asymptotic distributions for the proposed ratio and estimators are established. A bias‐corrected empirical likelihood approach to inference for the parameters of interest is developed, and the residual‐adjusted empirical log‐likelihood ratio is shown to be asymptotically chi‐squared. These results can be used to construct a class of approximate pointwise confidence intervals and simultaneous bands for the regression functions and their derivatives. Owing to our bias correction for the empirical likelihood ratio, the accuracy of the obtained confidence region is not only improved, but also a data‐driven algorithm can be used for selecting an optimal bandwidth to estimate the regression functions and their derivatives. A simulation study is conducted to compare the empirical likelihood method with the normal approximation‐based method in terms of coverage accuracies and average widths of the confidence intervals/bands. An application of this method is illustrated using a real data set.     

Empirical Likelihood Ratio Test for a Change-Point in Linear Regression Model

A nonparametric method based on the empirical likelihood is proposed to detect the change-point in the coefficient of linear regression models. The empirical likelihood ratio test statistic is proved to have the same asymptotic null distribution as that with classical parametric likelihood. Under some mild conditions, the maximum empirical likelihood change-point estimator is also shown to be consistent. The simulation results show the sensitivity and robustness of the proposed approach. The method is applied to some real datasets to illustrate the effectiveness.     

Jackknife Empirical Likelihood for the Accelerated Failure Time Model with Censored Data

Kendall and Gehan estimating functions are commonly used to estimate the regression parameter in accelerated failure time model with censored observations in survival analysis. In this paper, we apply the jackknife empirical likelihood method to overcome the computation difficulty about interval estimation. A Wilks’ theorem of jackknife empirical likelihood for U-statistic type estimating equations is established, which is used to construct the confidence intervals for the regression parameter. We carry out an extensive simulation study to compare the Wald-type procedure, the empirical likelihood method, and the jackknife empirical likelihood method. The proposed jackknife empirical likelihood method has a better performance than the existing methods. We also use a real data set to compare the proposed methods.     

Weighted composite quantile regression analysis for nonignorable missing data using nonresponse instrument

Efficient statistical inference on nonignorable missing data is a challenging problem. This paper proposes a new estimation procedure based on composite quantile regression (CQR) for linear regression models with nonignorable missing data, that is applicable even with high-dimensional covariates. A parametric model is assumed for modelling response probability, which is estimated by the empirical likelihood approach. Local identifiability of the proposed strategy is guaranteed on the basis of an instrumental variable approach. A set of data-based adaptive weights constructed via an empirical likelihood method is used to weight CQR functions. The proposed method is resistant to heavy-tailed errors or outliers in the response. An adaptive penalisation method for variable selection is proposed to achieve sparsity with high-dimensional covariates. Limiting distributions of the proposed estimators are derived. Simulation studies are conducted to investigate the finite sample performance of the proposed methodologies. An application to the ACTG 175 data is analysed.     

The Block Empirical Likelihood Method of the Semivarying Coefficient Model with Application to Longitudinal Data

In this article, we consider a semivarying coefficient model with application to longitudinal data. In order to accommodate the within-group correlation, we apply the block empirical likelihood procedure to semivarying coefficient longitudinal data model, and prove a nonparametric version of Wilks' theorem which can be used to construct the block empirical likelihood confidence region with asymptotically correct coverage probability for the parametric component. In comparison with normal approximations, the proposed method does not require a consistent estimator for the asymptotic covariance matrix, making it easier to conduct inference for the model's parametric component. Simulations demonstrate how the proposed method works.     

Jackknife empirical likelihood for the error variance in linear models

Variance estimation is a fundamental yet important problem in statistical modelling. In this paper, we propose jackknife empirical likelihood (JEL) methods for the error variance in a linear regression model. We prove that the JEL ratio converges to the standard chi-squared distribution. The asymptotic chi-squared properties for the adjusted JEL and extended JEL estimators are also established. Extensive simulation studies to compare the new JEL methods with the standard method in terms of coverage probability and interval length are conducted, and the simulation results show that our proposed JEL methods perform better than the standard method. We also illustrate the proposed methods using two real data sets.     

Generalized empirical likelihood inference in partially linear model for longitudinal data with missing response variables and error-prone covariates

In this article, we consider statistical inference for longitudinal partial linear models when the response variable is sometimes missing with missingness probability depending on the covariate that is measured with error. A generalized empirical likelihood (GEL) method is proposed by combining correction attenuation and quadratic inference functions. The method that takes into consideration the correlation within groups is used to estimate the regression coefficients. Furthermore, residual-adjusted empirical likelihood (EL) is employed for estimating the baseline function so that undersmoothing is avoided. The empirical log-likelihood ratios are proven to be asymptotically Chi-squared, and the corresponding confidence regions for the parameters of interest are then constructed. Compared with methods based on NAs, the GEL does not require consistent estimators for the asymptotic variance and bias. The numerical study is conducted to compare the performance of the EL and the normal approximation-based method, and a real example is analysed.     

Full likelihood inference in the Cox model with LTRC data when covariates are discrete

For the regression parameter β in the Cox model, there have been several estimates based on different types of approximated likelihood. For right-censored data, Ren and Zhou [Full likelihood inferences in the Cox model: an empirical approach. Ann Inst Statist Math. 2011;63:1005–1018] derive the full likelihood function for (β, F₀), where F₀ is the baseline distribution function in the Cox model. In this article, we extend their results to left-truncated and right-censored data with discrete covariates. Using the empirical likelihood parameterization, we obtain the full-profile likelihood function for β when covariates are discrete. Simulation results indicate that the maximum likelihood estimator outperforms Cox's partial likelihood estimator in finite samples.     

Empirical Likelihood Inference for the Cox Model with Time-dependent Coefficients via Local Partial Likelihood

Abstract.  The Cox model with time-dependent coefficients has been studied by a number of authors recently. In this paper, we develop empirical likelihood (EL) pointwise confidence regions for the time-dependent regression coefficients via local partial likelihood smoothing. The EL simultaneous confidence bands for a linear combination of the coefficients are also derived based on the strong approximation methods. The EL ratio is formulated through the local partial log-likelihood for the regression coefficient functions. Our numerical studies indicate that the EL pointwise/simultaneous confidence regions/bands have satisfactory finite sample performances. Compared with the confidence regions derived directly based on the asymptotic normal distribution of the local constant estimator, the EL confidence regions are overall tighter and can better capture the curvature of the underlying regression coefficient functions. Two data sets, the gastric cancer data and the Mayo Clinic primary biliary cirrhosis data, are analysed using the proposed method.     

Statistical diagnosis for non-parametric regression models with random right censorship based on the empirical likelihood method

In this paper, we consider statistical diagnostic for non-parametric regression models with right-censored data based on empirical likelihood. First, the primary model is transformed to the non-parametric regression model. Then, based on empirical likelihood methodology, we define some diagnostic statistics. At last, some simulation studies show that our proposed procedure can work fairly well.     

Empirical likelihood for linear regression models under imputation for missing responses

The authors study the empirical likelihood method for linear regression models. They show that when missing responses are imputed using least squares predictors, the empirical log‐likelihood ratio is asymptotically a weighted sum of chi‐square variables with unknown weights. They obtain an adjusted empirical log‐likelihood ratio which is asymptotically standard chi‐square and hence can be used to construct confidence regions. They also obtain a bootstrap empirical log‐likelihood ratio and use its distribution to approximate that of the empirical log‐likelihood ratio. A simulation study indicates that the proposed methods are comparable in terms of coverage probabilities and average lengths of confidence intervals, and perform better than a normal approximation based method.     

Two Adjusted Empirical-Likelihood-Based Methods in Generalized Varying-Coefficient Partially Linear Model

An empirical likelihood method was proposed by Owen and has been extended to many semiparametric and nonparametric models with a continuous response variable. However, there has been less attention focused on the generalized regression model. This article systematically studies two adjusted empirical-likelihood-based methods in the generalized varying-coefficient partially linear models. Based on the popular profile likelihood estimation procedure, the new adjusted empirical likelihood technology for the parameter is established and the resulting statistics are shown to be asymptotically standard chi-square distributed. Further, the adjusted empirical-likelihood-based confidence regions are established, and an efficient adjusted profile empirical-likelihood-based confidence intervals/regions for any components of the parameter, which are of primary interest, is also constructed. Their asymptotic properties are also derived. Some numerical studies are carried out to illustrate the performance of the proposed inference procedures.     

Empirical likelihood inference for the regression model of mean quality‐adjusted lifetime with censored data

The authors consider the empirical likelihood method for the regression model of mean quality‐adjusted lifetime with right censoring. They show that an empirical log‐likelihood ratio for the vector of the regression parameters is asymptotically a weighted sum of independent chi‐squared random variables. They adjust this empirical log‐likelihood ratio so that the limiting distribution is a standard chi‐square and construct corresponding confidence regions. Simulation studies lead them to conclude that empirical likelihood methods outperform the normal approximation methods in terms of coverage probability. They illustrate their methods with a data example from a breast cancer clinical trial study.     

Instrumental variable-based empirical likelihood inferences for varying-coefficient models with error-prone covariates

This paper presents the empirical likelihood inferences for a class of varying-coefficient models with error-prone covariates. We focus on the case that the covariance matrix of the measurement errors is unknown and neither repeated measurements nor validation data are available. We propose an instrumental variable-based empirical likelihood inference method and show that the proposed empirical log-likelihood ratio is asymptotically chi-squared. Then, the confidence intervals for the varying-coefficient functions are constructed. Some simulation studies and a real data application are used to assess the finite sample performance of the proposed empirical likelihood procedure.     

Empirical Likelihood Intervals for Conditional Value‐at‐Risk in Heteroscedastic Regression Models

Abstract. Non‐parametric regression models have been studied well including estimating the conditional mean function, the conditional variance function and the distribution function of errors. In addition, empirical likelihood methods have been proposed to construct confidence intervals for the conditional mean and variance. Motivated by applications in risk management, we propose an empirical likelihood method for constructing a confidence interval for the pth conditional value‐at‐risk based on the non‐parametric regression model. A simulation study shows the advantages of the proposed method.     

Empirical likelihood inference for parameters in a partially linear errors-in-variables model

In this paper, we consider the application of the empirical likelihood method to a partially linear model with measurement errors in the non-parametric part. It is shown that the empirical log-likelihood ratio at the true parameters converges to the standard chi-square distribution. Furthermore, we obtain the maximum empirical likelihood estimate of the unknown parameter by using the empirical log-likelihood ratio function, and the resulting estimator is shown to be asymptotically normal. Some simulations and an application are conducted to illustrate the proposed method.     

Empirical Likelihood for the Additive Hazards Model with Current Status Data

We investigate empirical likelihood for the additive hazards model with current status data. An empirical log-likelihood ratio for a vector or subvector of regression parameters is defined and its limiting distribution is shown to be a standard chi-squared distribution. The proposed inference procedure enables us to make empirical likelihood-based inference for the regression parameters. Finite sample performance of the proposed method is assessed in simulation studies to compare with that of a normal approximation method, it shows that the empirical likelihood method provides more accurate inference than the normal approximation method. A real data example is used for illustration.     

Empirical Likelihood Based Synthetic Data Method for Censored Regression Analysis

In this article, we propose a new empirical likelihood method for linear regression analysis with a right censored response variable. The method is based on the synthetic data approach for censored linear regression analysis. A log-empirical likelihood ratio test statistic for the entire regression coefficients vector is developed and we show that it converges to a standard chi-squared distribution. The proposed method can also be used to make inferences about linear combinations of the regression coefficients. Moreover, the proposed empirical likelihood ratio provides a way to combine different normal equations derived from various synthetic response variables. Maximizing this empirical likelihood ratio yields a maximum empirical likelihood estimator which is asymptotically equivalent to the solution of the estimating equation that are optimal linear combination of the original normal equations. It improves the estimation efficiency. The method is illustrated by some Monte Carlo simulation studies as well as a real example.     

Two-sample high-dimensional empirical likelihood

In this paper, we apply empirical likelihood for two-sample problems with growing high dimensionality. Our results are demonstrated for constructing confidence regions for the difference of the means of two p-dimensional samples and the difference in value between coefficients of two p-dimensional sample linear model. We show that empirical likelihood based estimator has the efficient property. That is, as p → ∞ for high-dimensional data, the limit distribution of the EL ratio statistic for the difference of the means of two samples and the difference in value between coefficients of two-sample linear model is asymptotic normal distribution. Furthermore, empirical likelihood (EL) gives efficient estimator for regression coefficients in linear models, and can be as efficient as a parametric approach. The performance of the proposed method is illustrated via numerical simulations.