Generalized empirical likelihood inference in partially linear model for longitudinal data with missing response variables and error-prone covariates

In this article, we consider statistical inference for longitudinal partial linear models when the response variable is sometimes missing with missingness probability depending on the covariate that is measured with error. A generalized empirical likelihood (GEL) method is proposed by combining correction attenuation and quadratic inference functions. The method that takes into consideration the correlation within groups is used to estimate the regression coefficients. Furthermore, residual-adjusted empirical likelihood (EL) is employed for estimating the baseline function so that undersmoothing is avoided. The empirical log-likelihood ratios are proven to be asymptotically Chi-squared, and the corresponding confidence regions for the parameters of interest are then constructed. Compared with methods based on NAs, the GEL does not require consistent estimators for the asymptotic variance and bias. The numerical study is conducted to compare the performance of the EL and the normal approximation-based method, and a real example is analysed.     

Block empirical likelihood for longitudinal partially linear regression models

The authors propose a block empirical likelihood procedure to accommodate the within‐group correlation in longitudinal partially linear regression models. This leads them to prove a nonparametric version of the Wilks theorem. In comparison with normal approximations, their method does not require a consistent estimator for the asymptotic covariance matrix, which makes it easier to conduct inference on the parametric component of the model. An application to a longitudinal study on fluctuations of progesterone level in a menstrual cycle is used to illustrate the procedure developed here.     

Weighted empirical likelihood for generalized linear models with longitudinal data

In this paper, we introduce the empirical likelihood (EL) method to longitudinal studies. By considering the dependence within subjects in the auxiliary random vectors, we propose a new weighted empirical likelihood (WEL) inference for generalized linear models with longitudinal data. We show that the weighted empirical likelihood ratio always follows an asymptotically standard chi-squared distribution no matter which working weight matrix that we have chosen, but a well chosen working weight matrix can improve the efficiency of statistical inference. Simulations are conducted to demonstrate the accuracy and efficiency of our proposed WEL method, and a real data set is used to illustrate the proposed method.     

Empirical likelihood inference for parameters in a partially linear errors-in-variables model

In this paper, we consider the application of the empirical likelihood method to a partially linear model with measurement errors in the non-parametric part. It is shown that the empirical log-likelihood ratio at the true parameters converges to the standard chi-square distribution. Furthermore, we obtain the maximum empirical likelihood estimate of the unknown parameter by using the empirical log-likelihood ratio function, and the resulting estimator is shown to be asymptotically normal. Some simulations and an application are conducted to illustrate the proposed method.     

Empirical likelihood for parameters in an additive partially linear errors-in-variables model with longitudinal data

Empirical likelihood inferences for the parameter component in an additive partially linear errors-in-variables model with longitudinal data are investigated in this article. A corrected-attenuation block empirical likelihood procedure is used to estimate the regression coefficients, a corrected-attenuation block empirical log-likelihood ratio statistic is suggested and its asymptotic distribution is obtained. Compared with the method based on normal approximations, our proposed method does not require any consistent estimator for the asymptotic variance and bias. Simulation studies indicate that our proposed method performs better than the method based on normal approximations in terms of relatively higher coverage probabilities and smaller confidence regions. Furthermore, an example of an air pollution and health data set is used to illustrate the performance of the proposed method.     

Inferences on partial linear models with right censored data by empirical likelihood

ABSTRACT

This article considers inference for partial linear models with right censored data. We use empirical likelihood based on the Buckley and James (1979 Buckley, J., James, I. (1979). Linear regression with censored data. Biometrika 66:429–436.[Crossref], [Web of Science ®] , [Google Scholar]) estimating equation to derive the confidence region for the regression parameter. We introduce an adjusted empirical likelihood ratio statistic for the parameter of interest and show that its limiting distribution is standard chi-square. A simulation is carried out to compare our method with the synthetic data approach in Wang and Li (2002 Wang, Q.-H., Li, G. (2002). Empirical Likelihood Semiparametric Regression Analysis under Random Censorship. J. Multivariate Anal. 83:469–486.[Crossref], [Web of Science ®] , [Google Scholar]).     

Empirical likelihood inference in mixture of semiparametric varying-coefficient models for longitudinal data with non-ignorable dropout

In this paper, empirical likelihood inference in mixture of semiparametric varying-coefficient models for longitudinal data with non-ignorable dropout is investigated. We estimate the non-parametric function based on the estimating equations and the local linear profile-kernel method. An empirical log-likelihood ratio statistic for parametric components is proposed to construct confidence regions and is shown to be an asymptotically chi-squared distribution. The non-parametric version of Wilk's theorem is also derived. A simulation study is undertaken to illustrate the finite sample performance of the proposed method.     

Adjusted empirical likelihood inference for additive hazards regression

ABSTRACT

This article develops an adjusted empirical likelihood (EL) method for the additive hazards model. The adjusted EL ratio is shown to have a central chi-squared limiting distribution under the null hypothesis. We also evaluate its asymptotic distribution as a non central chi-squared distribution under the local alternatives of order n^{? 1/2}, deriving the expression for the asymptotic power function. Simulation studies and a real example are conducted to evaluate the finite sample performance of the proposed method. Compared with the normal approximation-based method, the proposed method tends to have more larger empirical power and smaller confidence regions with comparable coverage probabilities.     

Empirical likelihood inference for partial functional linear model with missing responses

In this paper, we consider the empirical likelihood inferences of the partial functional linear model with missing responses. Two empirical log-likelihood ratios of the parameters of interest are constructed, and the corresponding maximum empirical likelihood estimators of parameters are derived. Under some regularity conditions, we show that the proposed two empirical log-likelihood ratios are asymptotic standard Chi-squared. Thus, the asymptotic results can be used to construct the confidence intervals/regions for the parameters of interest. We also establish the asymptotic distribution theory of corresponding maximum empirical likelihood estimators. A simulation study indicates that the proposed methods are comparable in terms of coverage probabilities and average lengths of confidence intervals. An example of real data is also used to illustrate our proposed methods.     

Interval-valued data regression using partial linear model

Semi-parametric modelling of interval-valued data is of great practical importance, as exampled by applications in economic and financial data analysis. We propose a flexible semi-parametric modelling of interval-valued data by integrating the partial linear regression model based on the Center & Range method, and investigate its estimation procedure. Furthermore, we introduce a test statistic that allows one to decide between a parametric linear model and a semi-parametric model, and approximate its null asymptotic distribution based on wild Bootstrap method to obtain the critical values. Extensive simulation studies are carried out to evaluate the performance of the proposed methodology and the new test. Moreover, several empirical data sets are analysed to document its practical applications.     

Improved likelihood inference for the shape parameter in Weibull regression

We obtain adjustments to the profile likelihood function in Weibull regression models with and without censoring. Specifically, we consider two different modified profile likelihoods: (i) the one proposed by Cox and Reid [Cox, D.R. and Reid, N., 1987, Parameter orthogonality and approximate conditional inference. Journal of the Royal Statistical Society B, 49, 1–39.], and (ii) an approximation to the one proposed by Barndorff–Nielsen [Barndorff–Nielsen, O.E., 1983, On a formula for the distribution of the maximum likelihood estimator. Biometrika, 70, 343–365.], the approximation having been obtained using the results by Fraser and Reid [Fraser, D.A.S. and Reid, N., 1995, Ancillaries and third-order significance. Utilitas Mathematica, 47, 33–53.] and by Fraser et al. [Fraser, D.A.S., Reid, N. and Wu, J., 1999, A simple formula for tail probabilities for frequentist and Bayesian inference. Biometrika, 86, 655–661.]. We focus on point estimation and likelihood ratio tests on the shape parameter in the class of Weibull regression models. We derive some distributional properties of the different maximum likelihood estimators and likelihood ratio tests. The numerical evidence presented in the paper favors the approximation to Barndorff–Nielsen's adjustment.     

Kernel-based global MLE of partial linear random effects models for longitudinal data

Random effects models have been playing a critical role for modelling longitudinal data. However, there are little studies on the kernel-based maximum likelihood method for semiparametric random effects models. In this paper, based on kernel and likelihood methods, we propose a pooled global maximum likelihood method for the partial linear random effects models. The pooled global maximum likelihood method employs the local approximations of the nonparametric function at a group of grid points simultaneously, instead of one point. Gaussian quadrature is used to approximate the integration of likelihood with respect to random effects. The asymptotic properties of the proposed estimators are rigorously studied. Simulation studies are conducted to demonstrate the performance of the proposed approach. We also apply the proposed method to analyse correlated medical costs in the Medical Expenditure Panel Survey data set.     

Robust inference in generalized linear models for longitudinal data

The author develops a robust quasi‐likelihood method, which appears to be useful for down‐weighting any influential data points when estimating the model parameters. He illustrates the computational issues of the method in an example. He uses simulations to study the behaviour of the robust estimates when data are contaminated with outliers, and he compares these estimates to those obtained by the ordinary quasi‐likelihood method.     

Empirical likelihood for high-dimensional partially linear model with martingale difference errors

In this paper, we focus on the empirical likelihood (EL) inference for high-dimensional partially linear model with martingale difference errors. An empirical log-likelihood ratio statistic of unknown parameter is constructed and is shown to have asymptotically normality distribution under some suitable conditions. This result is different from those derived before. Furthermore, an empirical log-likelihood ratio for a linear combination of unknown parameter is also proposed and its asymptotic distribution is chi-squared. Based on these results, the confidence regions both for unknown parameter and a linear combination of parameter can be obtained. A simulation study is carried out to show that our proposed approach performs better than normal approximation-based method.     

Full likelihood inference in the Cox model with LTRC data when covariates are discrete

For the regression parameter β in the Cox model, there have been several estimates based on different types of approximated likelihood. For right-censored data, Ren and Zhou [Full likelihood inferences in the Cox model: an empirical approach. Ann Inst Statist Math. 2011;63:1005–1018] derive the full likelihood function for (β, F₀), where F₀ is the baseline distribution function in the Cox model. In this article, we extend their results to left-truncated and right-censored data with discrete covariates. Using the empirical likelihood parameterization, we obtain the full-profile likelihood function for β when covariates are discrete. Simulation results indicate that the maximum likelihood estimator outperforms Cox's partial likelihood estimator in finite samples.     

Empirical likelihood for generalized linear models with fixed and adaptive designs

Empirical likelihood inference for generalized linear models with fixed and adaptive designs is considered. It is shown that the empirical log-likelihood ratio at the true parameters converges to the standard chi-square distribution. Furthermore, we obtain the maximum empirical likelihood estimate of the unknown parameter and the resulting estimator is shown to be asymptotically normal. Some simulations are conducted to illustrate the proposed method.     

Two-sample high-dimensional empirical likelihood

In this paper, we apply empirical likelihood for two-sample problems with growing high dimensionality. Our results are demonstrated for constructing confidence regions for the difference of the means of two p-dimensional samples and the difference in value between coefficients of two p-dimensional sample linear model. We show that empirical likelihood based estimator has the efficient property. That is, as p → ∞ for high-dimensional data, the limit distribution of the EL ratio statistic for the difference of the means of two samples and the difference in value between coefficients of two-sample linear model is asymptotic normal distribution. Furthermore, empirical likelihood (EL) gives efficient estimator for regression coefficients in linear models, and can be as efficient as a parametric approach. The performance of the proposed method is illustrated via numerical simulations.     

缺失数据下广义线性模型的经验似然推断

利用经验似然方法,讨论缺失数据下广义线性模型中参数的置信域问题,得到了对数经验似然比统计量的渐近分布为标准卡方分布;给出参数的一些估计量及其渐近分布,利用数据模拟解释了所提出的方法。     

Robust empirical likelihood for linear models under median constraints

In this paper, we consider the application of the empirical likelihood for

linear models under median constraints in view of robustness. For two simple median constraints, it is shown that conditions to ensure the consistency of the empirical likelihood confidence regions can be surprisingly relaxed compared with the normal approach under L norm. However, the coverage accuracy of the empirical likelihood confidence regions based on simple median constrains cannot be improved because of the discontinuity of the constraints. Therefore, a smoothed version of median constraint is proposed and a general theory is established to ensure its validity.