Bayesian parametric accelerated failure time spatial model and its application to prostate cancer

Prostate cancer (PrCA) is the most common cancer diagnosed in American men and the second leading cause of death from malignancies. There are large geographical variation and racial disparities existing in the survival rate of PrCA. Much work on the spatial survival model is based on the proportional hazards (PH) model, but few focused on the accelerated failure time (AFT) model. In this paper, we investigate the PrCA data of Louisiana from the Surveillance, Epidemiology, and End Results program and the violation of the PH assumption suggests that the spatial survival model based on the AFT model is more appropriate for this data set. To account for the possible extra-variation, we consider spatially referenced independent or dependent spatial structures. The deviance information criterion is used to select a best-fitting model within the Bayesian frame work. The results from our study indicate that age, race, stage, and geographical distribution are significant in evaluating PrCA survival.     

A new test for the presence of a normal mixture distribution based on the posterior Bayes factor

We present a new test for the presence of a normal mixture distribution, based on the posterior Bayes factor of Aitkin (1991). The new test has slightly lower power than the likelihood ratio test. It does not require the computation of the MLEs of the parameters or a search for multiple maxima, but requires computations based on classification likelihood assignments of observations to mixture components.     

Marshall-Olkin extended weibull distribution and its application to censored data

In this paper we show that the Marshall-Olkin extended Weibull distribution can be obtained as a compound distribution with mixing exponential distribution. In addition, we provide simple sufficient conditions for the shape of the hazard rate function of the distribution. Moreover, we extend the considered distribution to accommodate randomly right censored data. Finally, application of the extended distribution to a data set representing the remission times of bladder cancer patients is given and its goodness-of-fit is demonstrated.     

Q型系统聚类分析中的统计检验问题

Q型系统聚类分析已经越来越成为人们广泛应用的多元统计分析方法。然而在应用中盲目套用系统聚类分析方法的情况很多，并对聚类分析方法的适用性、聚类过程的合理性、聚类结果的有效性等问题分析重视不够，更谈不上对聚类分析进行统计检验。因此，为了更好地应用Q型系统聚类分析，就应对Q型系统聚类分析结果进行统计检验并建立统计检验体系。Q型系统聚类分析统计检验体系主要包括：Q型系统聚类分析结果的有效性检验；聚类分析类（组）数选择合理性检验；聚类变量的显著性检验。     

On the construction of exact lower confidence bounds on the distance between any two ranked location parameters of K populations

In this paper, an exact lower confidence bound on the distance between any two ranked location parameters of k populations is derived. This confidence bound contains the confidence bounds of Kim (1986) and of Chen, Xiong and Lam (1993) as special cases.     

Generalized manova double linear hypothesis with double linear restrictions

For the generalized MANOVA model of Potthoff and Roy [7], Gleser and Olkin [3] give a likelihood ratio test criterion for testing double linear parametric functions of the regression parameters. Their theory is extended in this paper to the testing of double linear parametric functions with double linear restrictions on the parameters. The theory is presented in terms of the original variates unlike Gleser and Olkin [3] who resort to canonical transformations of the original variates.     

Comparisons of Test Statistics Arising from Marginal Analyses of Multivariate Survival Data

We investigate the properties of several statistical tests for comparing treatment groups with respect to multivariate survival data, based on the marginal analysis approach introduced by Wei, Lin and Weissfeld [Regression Analysis of multivariate incomplete failure time data by modelling marginal distributians, JASA vol. 84 pp. 1065–1073]. We consider two types of directional tests, based on a constrained maximization and on linear combinations of the unconstrained maximizer of the working likelihood function, and the omnibus test arising from the same working likelihood. The directional tests are members of a larger class of tests, from which an asymptotically optimal test can be found. We compare the asymptotic powers of the tests under general contiguous alternatives for a variety of settings, and also consider the choice of the number of survival times to include in the multivariate outcome. We illustrate the results with simulations and with the results from a clinical trial examining recurring opportunistic infections in persons with HIV.     

Properties of a One-Sided Likelihood Ratio Test as Applied to Pool Screening

In the control of tropical disease, data are typically collected using pool screening design. When eradication programs have been in place for a period of time, researchers are interested in testing whether the disease prevalence is below a certain target level using one-sided likelihood ratio test (LRT). We will investigate the finite and large-sample properties of this test statistic. Based on simulations, if the number of pools is not large enough, the LRT has inflated type I error rate. Consequently, researchers will make the critical mistake of stopping the treatment when the target level has not been reached.     

Testtesting for the equality of scale parameters of k(> 2) exponential populations based on complete and type ii censored samples

This paper is concerned with testing the equality of scale parameters of K(> 2) two-parameter exponential distributions in presence of unspecified location parameters based on complete and type II censored samples. We develop a marginal likelihood ratio statistic, a quadratic statistic (Qu) (Nelson, 1982) based on maximum marginal likelihood estimates of the scale parameters under the null and the alternative hypotheses, a C(a) statistic (CPL) (Neyman, 1959) based on the profile likelihood estimate of the scale parameter under the null hypothesis and an extremal scale parameter ratio statistic (ESP) (McCool, 1979). We show that the marginal likelihood ratio statistic is equivalent to the modified Bartlett test statistic. We use Bartlett's small sample correction to the marginal likelihood ratio statistic and call it the modified marginal likelihood ratio statistic (MLB). We then compare the four statistics, MLBi Qut CPL and ESP in terms of size and power by using Monte Carlo simulation experiments. For the variety of sample sizes and censoring combinations and nominal levels considered the statistic MLB holds nominal level most accurately and based on empirically calculated critical values, this statistic performs best or as good as others in most situations. Two examples are given.     

A bayesian analysis of interrelated bernoulli processes with an application for clinical trials

Prior information regarding the interrelation of two Bernoulli processes may justify a clinical trial designed to corroborate this information. Antelman (1973) has studied the Dirichlet-beta which permits the expression of the prior knowledge of such interrelation. However, use of this prior distribution leads to complicated and intractable analyses. Alternately, such prior information regarding the interrelation of the processes may be adequately summarized by a simple Dirichlet distribution. Procedures for testing hypotheses regarding a priori interrelations of the success probabilities of the processes are given. Exact expressions for the posterior probabi1ities of these hypotheses are shown to be approximately equal to weighted p-values or 1ikelihood ratios.     

Evaluating the relative merits of competing models based on empirical likelihood ratio test

Competing models arise naturally in many research fields, such as survival analysis and economics, when the same phenomenon of interest is explained by different researcher using different theories or according to different experiences. The model selection problem is therefore remarkably important because of its great importance to the subsequent inference; Inference under a misspecified or inappropriate model will be risky. Existing model selection tests such as Vuong's tests [26 Q.H. Vuong, Likelihood ratio test for model selection and non-nested hypothesis, Econometrica 57 (1989), pp. 307–333. doi: 10.2307/1912557[Crossref], [Web of Science ®] , [Google Scholar]] and Shi's non-degenerate tests [21 X. Shi, A non-degenerate Vuong test, Quant. Econ. 6 (2015), pp. 85–121. doi: 10.3982/QE382[Crossref], [Web of Science ®] , [Google Scholar]] suffer from the variance estimation and the departure of the normality of the likelihood ratios. To circumvent these dilemmas, we propose in this paper an empirical likelihood ratio (ELR) tests for model selection. Following Shi [21 X. Shi, A non-degenerate Vuong test, Quant. Econ. 6 (2015), pp. 85–121. doi: 10.3982/QE382[Crossref], [Web of Science ®] , [Google Scholar]], a bias correction method is proposed for the ELR tests to enhance its performance. A simulation study and a real-data analysis are provided to illustrate the performance of the proposed ELR tests.     

The performance of model averaged tail area confidence intervals

We investigate the exact coverage and expected length properties of the model averaged tail area (MATA) confidence interval proposed by Turek and Fletcher, CSDA, 2012, in the context of two nested, normal linear regression models. The simpler model is obtained by applying a single linear constraint on the regression parameter vector of the full model. For given length of response vector and nominal coverage of the MATA confidence interval, we consider all possible models of this type and all possible true parameter values, together with a wide class of design matrices and parameters of interest. Our results show that, while not ideal, MATA confidence intervals perform surprisingly well in our regression scenario, provided that we use the minimum weight within the class of weights that we consider on the simpler model.     

Notes on Test Homogeneity of the Odds Ratio in Matched Pairs Under Stratified Sampling: A Monte Carlo Evaluation

Using Monte Carlo simulation, we compare the performance of five asymptotic test procedures and a randomized permutation test procedure for testing the homogeneity of odds ratio under the stratified matched-pair design. We note that the weighted-least-square test procedure is liberal, while Pearson's goodness-of-fit (PGF) test procedure with the continuity correction is conservative. We note that PGF without the continuity correction, the conditional likelihood ratio test procedure, and the randomized permutation test procedure can generally perform well with respect to Type I error. We use the data taken from a case–control study regarding the endometrial cancer incidence published elsewhere to illustrate the use of these test procedures.     

Bayes estimation of Gompertz distribution parameters and acceleration factor under partially accelerated life tests with type-I censoring

In this paper, the Bayesian approach is applied to the estimation problem in the case of step stress partially accelerated life tests with two stress levels and type-I censoring. Gompertz distribution is considered as a lifetime model. The posterior means and posterior variances are derived using the squared-error loss function. The Bayes estimates cannot be obtained in explicit forms. Approximate Bayes estimates are computed using the method of Lindley [D.V. Lindley, Approximate Bayesian methods, Trabajos Estadistica 31 (1980), pp. 223–237]. The advantage of this proposed method is shown. The approximate Bayes estimates obtained under the assumption of non-informative priors are compared with their maximum likelihood counterparts using Monte Carlo simulation.     

Homogeneity of variances in normal linear regression with a change point

Two methods for testing the equality of variances in straight lines regression with a change point are considered. One is likelihood ratio test and the other is Bayesian confidence interval, based on the highest posterior density for the ratio of variances, using non-informative priors. Methods are applied to the renal transplant data analyzed by Smith and Cook(1980) and Stephens(1994).     

Data-driven tests of uniformity on product manifolds

Data-driven versions of Sobolev tests of uniformity on compact Riemannian manifolds are reviewed and their large-sample asymptotic properties are given. A variant which is suitable for product manifolds is introduced. Data-driven goodness-of-fit tests of multivariate distributions are derived from data-driven tests of uniformity on tori.     

基于加权似然比检验的监控线性曲线的控制图

文章提出了一种基于加权似然比检验的阶段二监控线性曲线的控制图,称为WLRT图,并通过平均运行长度来衡量控制图的性能表现。模拟结果表明,WLRT图对于线性曲线的截距、斜率、标准差的变化及截距和斜率同时变化都具有很好的检测能力。通过与其他几种控制图的性能比较,得出WLRT图能较快地发现过程变化,而且设计简单、操作方便。     

Estimation under modified Weibull distribution based on right censored generalized order statistics

In this paper, the maximum likelihood (ML) and Bayes, by using Markov chain Monte Carlo (MCMC), methods are considered to estimate the parameters of three-parameter modified Weibull distribution (MWD(β, τ, λ)) based on a right censored sample of generalized order statistics (gos). Simulation experiments are conducted to demonstrate the efficiency of the proposed methods. Some comparisons are carried out between the ML and Bayes methods by computing the mean squared errors (MSEs), Akaike's information criteria (AIC) and Bayesian information criteria (BIC) of the estimates to illustrate the paper. Three real data sets from Weibull(α, β) distribution are introduced and analyzed using the MWD(β, τ, λ) and also using the Weibull(α, β) distribution. A comparison is carried out between the mentioned models based on the corresponding Kolmogorov–Smirnov (K–S) test statistic, {AIC and BIC} to emphasize that the MWD(β, τ, λ) fits the data better than the other distribution. All parameters are estimated based on type-II censored sample, censored upper record values and progressively type-II censored sample which are generated from the real data sets.     

检验式设定错误对时间序列单位根检验小样本性质的影响

首先对单位根检验的两类常见的数据生成系统进行比较,然后利用蒙特卡洛实验研究了时间序列单位根检验式的设定问题。研究发现在利用DF检验和DF-GLS检验进行时间序列的单位根检验时,检验式设定错误直接影响着检验结果,尤其在推断时间序列是趋势平稳过程还是有时间趋势项的随机游走过程或有二阶时间趋势多项式的随机游走过程时,检验式的错误设定很容易将趋势平稳过程误判为非平稳过程。