A smoothed Q‐learning algorithm for estimating optimal dynamic treatment regimes

In this paper, we propose a smoothed Q‐learning algorithm for estimating optimal dynamic treatment regimes. In contrast to the Q‐learning algorithm in which nonregular inference is involved, we show that, under assumptions adopted in this paper, the proposed smoothed Q‐learning estimator is asymptotically normally distributed even when the Q‐learning estimator is not and its asymptotic variance can be consistently estimated. As a result, inference based on the smoothed Q‐learning estimator is standard. We derive the optimal smoothing parameter and propose a data‐driven method for estimating it. The finite sample properties of the smoothed Q‐learning estimator are studied and compared with several existing estimators including the Q‐learning estimator via an extensive simulation study. We illustrate the new method by analyzing data from the Clinical Antipsychotic Trials of Intervention Effectiveness–Alzheimer's Disease (CATIE‐AD) study.     

An asymptotic confidence interval for the process capability index Cpm

Abstract

The use of indices as an estimation tool of process capability is long-established among the statistical quality professionals. Numerous capability indices have been proposed in last few years. C_pm constitutes one of the most widely used capability indices and its estimation has attracted much interest. In this paper, we propose a new method for constructing an approximate confidence interval for the index C_pm. The proposed method is based on the asymptotic distribution of the index C_pm obtained by the Delta Method. Under some regularity conditions, the distribution of an estimator of the process capability index C_pm is asymptotically normal.     

Two-queue polling systems with switching policy based on the queue that is not being served

We study a system of two non-identical and separate M/M/1/? queues with capacities (buffers) C₁ < ∞ and C₂ = ∞, respectively, served by a single server that alternates between the queues. The server’s switching policy is threshold-based, and, in contrast to other threshold models, is determined by the state of the queue that is not being served. That is, when neither queue is empty while the server attends Q_i (i = 1, 2), the server switches to the other queue as soon as the latter reaches its threshold. When a served queue becomes empty we consider two switching scenarios: (i) Work-Conserving, and (ii) Non-Work-Conserving. We analyze the two scenarios using Matrix Geometric methods and obtain explicitly the rate matrix R, where its entries are given in terms of the roots of the determinants of two underlying matrices. Numerical examples are presented and extreme cases are investigated.     

A Bayesian procedure for assessing process performance based on the third-generation capability index

Capability indices that qualify process potential and process performance are practical tools for successful quality improvement activities and quality program implementation. Most existing methods to assess process capability were derived on the basis of the traditional frequentist point of view. This paper considers the problem of estimating and testing process capability based on the third-generation capability index C _pmk from the Bayesian point of view. We first derive the posterior probability p for the process under investigation is capable. The one-sided credible interval, a Bayesian analog of the classical lower confidence interval, can be obtained to assess process performance. To investigate the effectiveness of the derived results, a series of simulation was undertaken. The results indicate that the performance of the proposed Bayesian approach depends strongly on the value of ξ=(μ?T)/σ. It performs very well with the accurate coverage rate when μ is sufficiently far from T. In those cases, they have the same acceptable performance even though the sample size n is as small as 25.     

An Improved Approach for Estimating Product Performance Based on the Capability Index C pmk

In this article, we construct an improved procedure for estimating the process capability index C _pmk . We propose a new C _pmk lower-bound approach based on the GCI concept, and compare it with other existing methods. Based on the comparison results, we conclude with a recommendation, and construct a step-by-step procedure for the recommended approach to estimate the actual process capability C _pmk for various sample sizes. The lower bound attended by our recommended approach, indeed, improves other existing lower bound methods. We also investigate a real-world application to illustrate how we could apply the recommended approach to the actual manufacturing processes.     

Switching nonparametric regression models

We propose a methodology to analyse data arising from a curve that, over its domain, switches among J states. We consider a sequence of response variables, where each response y depends on a covariate x according to an unobserved state z. The states form a stochastic process and their possible values are j=1,?…?, J. If z equals j the expected response of y is one of J unknown smooth functions evaluated at x. We call this model a switching nonparametric regression model. We develop an Expectation–Maximisation algorithm to estimate the parameters of the latent state process and the functions corresponding to the J states. We also obtain standard errors for the parameter estimates of the state process. We conduct simulation studies to analyse the frequentist properties of our estimates. We also apply the proposed methodology to the well-known motorcycle dataset treating the data as coming from more than one simulated accident run with unobserved run labels.     

Nonparametric Benchmark Dose Estimation with Continuous Dose‐Response Data

We propose a new method for risk‐analytic benchmark dose (BMD) estimation in a dose‐response setting when the responses are measured on a continuous scale. For each dose level d, the observation X(d) is assumed to follow a normal distribution: . No specific parametric form is imposed upon the mean μ(d), however. Instead, nonparametric maximum likelihood estimates of μ(d) and σ are obtained under a monotonicity constraint on μ(d). For purposes of quantitative risk assessment, a ‘hybrid’ form of risk function is defined for any dose d as R(d) = P[X(d) < c], where c > 0 is a constant independent of d. The BMD is then determined by inverting the additional risk functionR_A(d) = R(d) ? R(0) at some specified value of benchmark response. Asymptotic theory for the point estimators is derived, and a finite‐sample study is conducted, using both real and simulated data. When a large number of doses are available, we propose an adaptive grouping method for estimating the BMD, which is shown to have optimal mean integrated squared error under appropriate designs.     

Multivariate process capability a bayesian perspective

In this paper an attempt has been made to examine the multivariate versions of the common process capability indices (PCI's) denoted by C_p and C_pk . Markov chain Monte Carlo (MCMC) methods are used to generate sampling distributions for the various PCI's from where inference is performed. Some Bayesian model checking techniques are developed and implemented to examine how well our model fits the data. Finally the methods are exemplified on a historical aircraft data set collected by the Pratt and Whitney Company.     

Comparison of two measures of association in two-way contingency tables

Stuart's (1953) measure of association in contingency tables, t_C, based on Kendall's (1962) t, is compared with Goodman and Kruskal's (1954, 1959, 1963, 1972) measure G. First, it is proved that |G| ≥ |t_C|; and then it is shown that the upper bound for the asymptotic variance of G is not necessarily always smaller than the upper bound for the asymptotic variance of t_C. It is proved, however, that the upper bound for the coefficient of variation of G cannot be larger in absolute value than the upper bound for the coefficient of variation of t_C. The asymptotic variance of t_C is also derived and hence we obtain an upper bound for this asymptotic variance which is sharper than Stuart's (1953) upper bound.     

The role of reversals in order‐restricted inference

A statistical model is said to be an order‐restricted statistical model when its parameter takes its values in a closed convex cone C of the Euclidean space. In recent years, order‐restricted likelihood ratio tests and maximum likelihood estimators have been criticized on the grounds that they may violate a cone order monotonicity (COM) property, and hence reverse the cone order induced by C. The authors argue here that these reversals occur only in the case that C is an obtuse cone, and that in this case COM is an inappropriate requirement for likelihood‐based estimates and tests. They conclude that these procedures thus remain perfectly reasonable procedures for order‐restricted inference.     

Probability-Based Process Capability Indices

This article deals with alternative process capability indices (PCIs) to traditional basic PCIs C _p , C _pk , and C _pm based on different fraction conforming type of probabilities. In view of various problems of constructing capability indices for univariate as well as multivariate set up, these alternative PCIs are very useful as compared to C _p , C _pk , and C _pm . Computing aspects of proposed PCIs are discussed for normal and non normal processes when process tolerance is symmetric as well as asymmetric. Generalization of these PCIs for multivariate set up is also discussed. Some simulation study results and real life problems are given for applications of proposed PCIs.     

Characterizations based on conditional expectations

For given real functionsg andh, first we give necessary and sufficient conditions such that there exists a random variableX satisfying thatE(g(X)|X≥y)=h(y)r _x (y),∀y ∈ C _x , whereC _x andT _X are the support and the failure rate function ofX, respectively. These extend the results of Ruiz and Navarro (1994) and Ghitany et al. (1995). Next we investigate necessary and sufficient conditions such thath(y)=E(g(X)|X≥y), for a given functionh. Support for this research was provided in part by the National Science Council of the Republic of China, Grant No. NSC 86-2115-M-110-014 and NSC 88-2118-M-110-001     

Penalized regression with model‐based penalties

Nonparametric regression techniques such as spline smoothing and local fitting depend implicitly on a parametric model. For instance, the cubic smoothing spline estimate of a regression function ∫ μ based on observations ti, Yi is the minimizer of Σ{Yi ‐ μ(ti)}² + λ∫(μ′′)². Since ∫(μ″)² is zero when μ is a line, the cubic smoothing spline estimate favors the parametric model μ(t) = α_o + α₁t. Here the authors consider replacing ∫(μ″)² with the more general expression ∫(Lμ)² where L is a linear differential operator with possibly nonconstant coefficients. The resulting estimate of μ performs well, particularly if Lμ is small. They present an O(n) algorithm for the computation of μ. This algorithm is applicable to a wide class of L's. They also suggest a method for the estimation of L. They study their estimates via simulation and apply them to several data sets.     

A combined control scheme for monitoring the frequency and size of an attribute event

A traffic accident can be considered as an example of the attribute events, and the number of the injured in each accident is called the event size. Some control charts have been developed for monitoring either the time interval (T) between the occurrences of an event or the event size (C) in each occurrence. This article studies the statistical monitoring of the attribute events in which T and C are monitored simultaneously and C is an integer. Essentially, it integrates a T chart and a C chart, and is therefore referred to as a T&C scheme. Our studies show that the new chart is more effective than an individual T chart or C chart for detecting the out-of-control status of the event, in particular for detecting downward shifts (sparse occurrence and/or small size). Another desirable feature of the T&C scheme is that its detection effectiveness is more invariable against different types of shifts (i.e. T shift, C shift and joint shift in T&C) compared with an individual T or C chart. The improvement in performance is achieved due to the simultaneous monitoring of T and C. The T&C scheme can be applied in manufacturing systems and especially in non-manufacturing sectors (e.g. supply chain management, health care industry, disaster management and security control).     

Weak Convergence of the Regularization Path in Penalized M‐Estimation

Abstract. We consider a function defined as the pointwise minimization of a doubly index random process. We are interested in the weak convergence of the minimizer in the space of bounded functions. Such convergence results can be applied in the context of penalized M‐estimation, that is, when the random process to minimize is expressed as a goodness‐of‐fit term plus a penalty term multiplied by a penalty weight. This weight is called the regularization parameter and the minimizing function the regularization path. The regularization path can be seen as a collection of estimators indexed by the regularization parameter. We obtain a consistency result and a central limit theorem for the regularization path in a functional sense. Various examples are provided, including the ?¹‐regularization path for general linear models, the ?¹‐ or ?²‐regularization path of the least absolute deviation regression and the Akaike information criterion.     

Variations of Q–Q Plots: The Power of Our Eyes!

In statistical modeling, we strive to specify models that resemble data collected in studies or observed from processes. Consequently, distributional specification and parameter estimation are central to parametric models. Graphical procedures, such as the quantile–quantile (Q–Q) plot, are arguably the most widely used method of distributional assessment, though critics find their interpretation to be overly subjective. Formal goodness of fit tests are available and are quite powerful, but only indicate whether there is a lack of fit, not why there is lack of fit. In this article, we explore the use of the lineup protocol to inject rigor into graphical distributional assessment and compare its power to that of formal distributional tests. We find that lineup tests are considerably more powerful than traditional tests of normality. A further investigation into the design of Q–Q plots shows that de-trended Q–Q plots are more powerful than the standard approach as long as the plot preserves distances in x and y to be the same. While we focus on diagnosing nonnormality, our approach is general and can be directly extended to the assessment of other distributions.     

A Study on the Robustness of G-Chart to Non-Normality

The G-chart is proposed by Riaz and Saghirr (2007 Riaz, M., Saghirr, A. (2007). Monitoring Process Variability using Gini's mean difference. Quality Technology and Quantitative Management 4:439–454.[Taylor & Francis Online] , [Google Scholar]) for monitoring the changes in the process variability more efficiently. This study investigates the influence of the parent population on the coefficients of the G-Chart. The appropriate values of the coefficients (b₂ and b₃) has been determined when the distributions of the processes are the normal, exponential, uniform, Laplace, and triangular. The false alarm rate and risk of type II error as performance measures of the G-chart are obtained. The robustness of the G-chart relative to Q- and R_Q-charts is studied. The efficiency of the G-chart relative to those of R-chart for detecting a shift in the process dispersion is examined. The results reveal that the proper attention to the parent population leads to the better performances of the G-chart. The G-chart is more robust than Q-chart and is slightly less efficient than R_Q-chart for detecting outliers. The G-chart is more efficient than R-chart to detect a shift for normal and non-normal processes.     

A General Class of Test Procedures for Left-Truncated and Right-Censored Data

When the distribution of one of the characteristics of a process is non normal, methods based on empirical percentiles suggest the use of several process capability indices (PCIs) which are similar to the usual C _p , C _pk , C _pm , and C _pmk indices. However most of these PCIs apply only to the case of symmetrical tolerances. To take into account the asymmetry of the tolerances as well as the asymmetry of the process distribution, new PCIs which improve the previous ones are proposed. In the end and in order to validate the method proposed here, we apply it to a real production case.