Nonparametric estimation of the bivariate cdf for arbitrarily censored data

Right, left or interval censored multivariate data can be represented by an intersection graph. Focussing on the bivariate case, the authors relate the structure of such an intersection graph to the support of the nonparametric maximum likelihood estimate (NPMLE) of the cumulative distribution function (CDF) for such data. They distinguish two types of non‐uniqueness of the NPMLE: representational, arising when the likelihood is unaffected by the distribution of the estimated probability mass within regions, and mixture, arising when the masses themselves are not unique. The authors provide a brief overview of estimation techniques and examine three data sets.     

Estimation and prediction of Marshall–Olkin extended exponential distribution under progressively type-II censored data

In this paper, we consider Marshall–Olkin extended exponential (MOEE) distribution which is capable of modelling various shapes of failure rates and aging criteria. The purpose of this paper is three fold. First, we derive the maximum likelihood estimators of the unknown parameters and the observed the Fisher information matrix from progressively type-II censored data. Next, the Bayes estimates are evaluated by applying Lindley’s approximation method and Markov Chain Monte Carlo method under the squared error loss function. We have performed a simulation study in order to compare the proposed Bayes estimators with the maximum likelihood estimators. We also compute 95% asymptotic confidence interval and symmetric credible interval along with the coverage probability. Third, we consider one-sample and two-sample prediction problems based on the observed sample and provide appropriate predictive intervals under classical as well as Bayesian framework. Finally, we analyse a real data set to illustrate the results derived.     

A Spline‐Based Semiparametric Maximum Likelihood Estimation Method for the Cox Model with Interval‐Censored Data

Abstract. We propose a spline‐based semiparametric maximum likelihood approach to analysing the Cox model with interval‐censored data. With this approach, the baseline cumulative hazard function is approximated by a monotone B‐spline function. We extend the generalized Rosen algorithm to compute the maximum likelihood estimate. We show that the estimator of the regression parameter is asymptotically normal and semiparametrically efficient, although the estimator of the baseline cumulative hazard function converges at a rate slower than root‐n. We also develop an easy‐to‐implement method for consistently estimating the standard error of the estimated regression parameter, which facilitates the proposed inference procedure for the Cox model with interval‐censored data. The proposed method is evaluated by simulation studies regarding its finite sample performance and is illustrated using data from a breast cosmesis study.     

On nonparametric maximum likelihood estimation with interval censoring and left truncation

Summary.  A graph theoretical approach is employed to describe the support set of the nonparametric maximum likelihood estimator for the cumulative distribution function given interval-censored and left-truncated data. A necessary and sufficient condition for the existence of a nonparametric maximum likelihood estimator is then derived. Two previously analysed data sets are revisited.     

Confidence Intervals for Current Status Data

Abstract.  The likelihood ratio statistic for testing pointwise hypotheses about the survival time distribution in the current status model can be inverted to yield confidence intervals (CIs). One advantage of this procedure is that CIs can be formed without estimating the unknown parameters that figure in the asymptotic distribution of the maximum likelihood estimator (MLE) of the distribution function. We discuss the likelihood ratio-based CIs for the distribution function and the quantile function and compare these intervals to several different intervals based on the MLE. The quantiles of the limiting distribution of the MLE are estimated using various methods including parametric fitting, kernel smoothing and subsampling techniques. Comparisons are carried out both for simulated data and on a data set involving time to immunization against rubella. The comparisons indicate that the likelihood ratio-based intervals are preferable from several perspectives.     

Fisher’s observed information matrix for location and scale parameters under type i censoring

An expression for Fisher's observed information matrix is given under type I censoring for any location-scale distribution under mild requirements. It is illustrated on a data set which has been analyzed by several authors.     

Analysis of progressively type-I interval censored competing risks data for a class of an exponential distribution

ABSTRACT

In this paper, we consider some problems of point estimation and point prediction when the competing risks data from a class of exponential distribution are progressive type-I interval censored. The maximum likelihood estimation and mid-point approximation method are proposed for the estimations of parameters. Also several point predictors of censored units such as the maximum likelihood predictor, the best unbiased predictor and the conditional median predictor are obtained. The methods discussed here are applied when the lifetime distributions of the latent failure times are independent and Weibull-distributed. Finally a simulation study is given by using Monte-Carlo simulations to compare the performances of the different methods and one data analysis has been presented for illustrative purposes.     

Empirical Likelihood For Censored Partial Linear Model Based On Imputed Value

This article aims at proposing a new type of empirical likelihood testing procedure based on the Wilks theorem and imputed value in censored partial linear model. The present study is mainly designed to use empirical likelihood (EL) method based on synthetic dependent data, and the result can not be applied directly due to the weights in it. In this article, a censored empirical log-likelihood ratio is introduced to tackle this problem. Particularly, we demonstrate that its limiting distribution is a standard chi-squared distribution with freedom of one. This method is used to calculate the p-value and construct the confidence interval. Some simulation studies are conducted to highlight the performance of the proposed EL method, and the results show that it performs well. Finally, an illustration is given using the Stanford Heart Transplant data.     

Maximum likeihood estimation of an intraclass correlation in a bivariate normal distribution with missing observations

The maximum likeihood estimate is considered for an intraclass correlation coefficent in a bivariate normal distribution when some observations on either of the varibles are missuing. The estimate is given as the soulution of a polynomial equation of degree seven. An approximate confidence interval and a test procedure for the intraclass correlation are constricted based on an asymptotic variance stabilizing transformation of the resulting estimator. The distributional results are also considered under violation of the normality assumption. A Monte Carlo study was performed to examine the finite sample properties of the maximum likelihood estimator and to evaluate the proposed procedures for hypotheses testing and interval estimation.     

Analysis of interval censored failure time data with competing risk

In this article, we analyze interval censored failure time data with competing risks. A new estimator for the cumulative incidence function is derived using an approximate likelihood and a test statistic to compare two samples is then obtained by extending Sun's test statistic. Small sample properties of the proposed methods are examined by conducting simulations and a cohort dataset from AIDS patients is analyzed as a real example.     

The Marshall-Olkin logistic-exponential distribution

We introduce a three-parameter extension of the exponential distribution which contains as sub-models the exponential, logistic-exponential and Marshall-Olkin exponential distributions. The new model is very flexible and its associated density function can be decreasing or unimodal. Further, it can produce all of the four major shapes of the hazard rate, that is, increasing, decreasing, bathtub and upside-down bathtub. Given that closed-form expressions are available for the survival and hazard rate functions, the new distribution is quite tractable. It can be used to analyze various types of observations including censored data. Computable representations of the quantile function, ordinary and incomplete moments, generating function and probability density function of order statistics are obtained. The maximum likelihood method is utilized to estimate the model parameters. A simulation study is carried out to assess the performance of the maximum likelihood estimators. Two actual data sets are used to illustrate the applicability of the proposed model.     

Combined multiple testing by censored empirical likelihood

We propose a new procedure for combining multiple tests in samples of right-censored observations. The new method is based on multiple constrained censored empirical likelihood where the constraints are formulated as linear functionals of the cumulative hazard functions. We prove a version of Wilks’ theorem for the multiple constrained censored empirical likelihood ratio, which provides a simple reference distribution for the test statistic of our proposed method. A useful application of the proposed method is, for example, examining the survival experience of different populations by combining different weighted log-rank tests. Real data examples are given using the log-rank and Gehan-Wilcoxon tests. In a simulation study of two sample survival data, we compare the proposed method of combining tests to previously developed procedures. The results demonstrate that, in addition to its computational simplicity, the combined test performs comparably to, and in some situations more reliably than previously developed procedures. Statistical software is available in the R package ‘emplik’.     

Parameter estimation under orthant restrictions

The authors consider the estimation of linear functions of a multivariate parameter under orthant restrictions. These restrictions are considered both for location models and for the Poisson distribution. For these models, situations are characterized for which the restricted maximum likelihood estimator dominates the unrestricted one for the estimation of any linear function of the parameter. The results obtained point directly to the importance of the dimension of the parameter space, the central direction of the cone and its vertex in these cases. Special attention is given to examples, such as the one‐way analysis of variance, where the estimation of individual interesting linear functions of the parameter, as the coordinates and the differences between them, is also treated.     

Empirical Likelihood Confidence Region for Parameters in Semi-linear Errors-in-Variables Models

Abstract.  This paper proposes a constrained empirical likelihood confidence region for a parameter in the semi-linear errors-in-variables model. The confidence region is constructed by combining the score function corresponding to the squared orthogonal distance with a constraint on the parameter, and it overcomes that the solution of limiting mean estimation equations is not unique. It is shown that the empirical log likelihood ratio at the true parameter converges to the standard chi-square distribution. Simulations show that the proposed confidence region has coverage probability which is closer to the nominal level, as well as narrower than those of normal approximation of generalized least squares estimator in most cases. A real data example is given.     

Reliability analysis of multicomponent stress–strength reliability from a bathtub-shaped distribution

In this paper, inference for a multicomponent stress–strength model is studied. When latent strength and stress random variables follow a bathtub-shaped distribution and the failure times are Type-II censored, the maximum likelihood estimate of the multicomponent stress–strength reliability (MSR) is established when there are common strength and stress parameters. Approximate confidence interval is also constructed by using the asymptotic distribution theory and delta method. Furthermore, another alternative generalized point and confidence interval estimators for the MSR are constructed based on pivotal quantities. Moreover, the likelihood and the pivotal quantities-based estimates for the MSR are also provided under unequal strength and stress parameter case. To compare the equivalence of the stress and strength parameters, the likelihood ratio test for hypothesis of interest is also provided. Finally, simulation studies and a real data example are given for illustration.     

The cosine geometric distribution with count data modeling

In this paper, a new two-parameter discrete distribution is introduced. It belongs to the family of the weighted geometric distribution (GD), with the feature of using a particular trigonometric weight. This configuration adds an oscillating property to the former GD which can be helpful in analyzing the data with over-dispersion, as developed in this study. First, we present the basic statistical properties of the new distribution, including the cumulative distribution function, hazard rate function and moment generating function. Estimation of the related model parameters is investigated using the maximum likelihood method. A simulation study is performed to illustrate the convergence of the estimators. Applications to two practical datasets are given to show that the new model performs at least as well as some competitors.     

Testing uniformity based on new entropy estimators

In this paper, we first introduce new entropy estimators for distributions with known and bounded supports. Our estimators are obtained by using constrained maximum likelihood estimation of cumulative distribution function for absolutely continuous distributions with known and bounded supports. We prove the consistency of our estimators. Then, we propose uniformity tests based on the proposed entropy estimators and compare their powers with the powers of other tests of uniformity. Our simulation results show that the proposed entropy estimators perform well in estimating entropy and testing uniformity.     

Estimating Percentiles of Time-to-Failure Distribution Obtained from a Linear Degradation Model Using Kernel Density Method

In this article, we propose a nonparametric estimator for percentiles of the time-to-failure distribution obtained from a linear degradation model using the kernel density method. The properties of the proposed kernel estimator are investigated and compared with well-known maximum likelihood and ordinary least squares estimators via a simulation technique. The mean squared error and the length of the bootstrap confidence interval are used as the basis criteria of the comparisons. The simulation study shows that the performance of the kernel estimator is acceptable as a general estimator. When the distribution of the data is assumed to be known, the maximum likelihood and ordinary least squares estimators perform better than the kernel estimator, while the kernel estimator is superior when the assumption of our knowledge of the data distribution is violated. A comparison among different estimators is achieved using a real data set.     

A case study of green tree frog population size estimation by repeated capture–mark–recapture method with individual tagging: a parametric bootstrap method vs Jolly–Seber method

This paper deals with estimation of a green tree frog population in an urban setting using repeated capture–mark–recapture (CMR) method over several weeks with an individual tagging system which gives rise to a complicated generalization of the hypergeometric distribution. Based on the maximum likelihood estimation, a parametric bootstrap approach is adopted to obtain interval estimates of the weekly population size which is the main objective of our work. The method is computation-based; and programming intensive to implement the algorithm for re-sampling. This method can be applied to estimate the population size of any species based on repeated CMR method at multiple time points. Further, it has been pointed out that the well-known Jolly–Seber method, which is based on some strong assumptions, produces either unrealistic estimates, or may have situations where its assumptions are not valid for our observed data set.     

Modelling interval data with Normal and Skew-Normal distributions

A parametric modelling for interval data is proposed, assuming a multivariate Normal or Skew-Normal distribution for the midpoints and log-ranges of the interval variables. The intrinsic nature of the interval variables leads to special structures of the variance–covariance matrix, which is represented by five different possible configurations. Maximum likelihood estimation for both models under all considered configurations is studied. The proposed modelling is then considered in the context of analysis of variance and multivariate analysis of variance testing. To access the behaviour of the proposed methodology, a simulation study is performed. The results show that, for medium or large sample sizes, tests have good power and their true significance level approaches nominal levels when the constraints assumed for the model are respected; however, for small samples, sizes close to nominal levels cannot be guaranteed. Applications to Chinese meteorological data in three different regions and to credit card usage variables for different card designations, illustrate the proposed methodology.