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A reduction in the ability to generate new neurons in the brain has been suggested to contribute to cognitive decline with advanced age. In an outbred model strain of Long-Evans rats, cognitive performance as a function of age is variable in assessments of hippocampal-dependent spatial memory. Recent research indicates that greater hippocampal neurogenesis accompanies diminished cognitive abilities in older Long-Evans rats. These findings imply that the role of neurogenesis might change between youth and old age, and that further work is needed to understand the potential benefits and liabilities that new neurons may afford an aging brain.  相似文献   
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This paper describes the GRASP computer aided design system for modelling and evaluating industrial robot workplaces. GRASP satisfies a range of simulation needs within the context of designing, implementing and operating industrial robotic systems. The GRASP software may be used to investigate robots operating by themselves or, more likely, as part of an integrated cell. Facilities within GRASP assist workplace layout, position and velocity evaluations, clash detection and co-ordination between items. A robot library exists and is being extended, and an embryo off-line programming facility has been used under restricted conditions. GRASP has been used to help solve a wide range of practical industrial robot problems and has proved itself technically, and also as an educational tool, by showing how a proposed system would operate. The paper describes the facilities within GRASP.  相似文献   
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Abstract

This paper describes the development of a method of data collection, which captures the complexity of living situations, family dynamics and key life events of teenagers. This ‘Life History Calendar’ was adapted from earlier life history calendar methods for a multidisciplinary intergenerational study. The new calendar is able to record details of 15 years of teenage participants’ lives and can be administered to teenagers and their parents to show changes over individual lives and difference between individuals in a cohort. Referring to some preliminary data, we show that the calendar is a practical and effective method of data collection, which will be useful to researchers and practitioners working with young people and their families.  相似文献   
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The living arrangements of young people in New Zealand are diverse and often complex. In this article we report the range of care and living arrangements of 209 15-year-old New Zealanders, 47 of whom identified as Māori. These young people were participants in the second generation of a cohort study. Data were collected from their parents via a life history calendar and analysed for variety and consistency of care arrangements, household membership and transitions. Few participants had a consistent pattern of parental care arrangements and most had experienced multiple changes in household composition and frequent changes of address. We conclude that the whānau/family lives of many young New Zealanders are complex and dynamic. These observations contrast with the conventional notions of family life that form the basis for New Zealand’s family policies. We argue that social policies and services impacting on young people need to reflect the lived reality of young people if they are to meet young people’s needs.  相似文献   
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There is evidence that smoking and alcohol consumption are paired behaviours among university students, but we know little about how New Zealand students engage in these behaviours. We estimated prevalence of daily and occasional smoking among university students, and associations of smoking with drinking patterns, demographics and smokefree policies of the university. This research was conducted with 2822 university students, aged 17–25, from five New Zealand universities who participated in an online health survey in 2013. Fourteen percent reported they currently smoke occasionally, and 3% reported smoking on a daily basis. Increasing age, living situation, drinking more often, and drinking more alcohol during drinking occasions were all associated with greater levels of smoking. Understanding patterns of smoking in relation to alcohol consumption may help efforts to further reduce smoking prevalence. Specifically, policy makers should consider approaches that de-couple tobacco and alcohol consumption, such as expanding the smokefree perimeter of bars and disallowing the sale of tobacco at premises licensed to sell alcohol.  相似文献   
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