Population growth and economic development

The paper deals with the relationship between the population growth and economic development in Yugoslavia and its republics, covering the period after the Second World War. Yugoslavia is a developing country with a specific demographic and economic structure which makes her unique in Europe. Its territory is comprised of both relatively developed regions where demographic transition is over, and underdeveloped regions with high natural increase of population where the demographic transition is only just beginning. Correlation and regression methods were used to quantify this relationship. The economic development and structural changes are discussed, relating to human factor. An adequate population policy through family planning is stressed as important in obtaining an increased return to scale with a more positive role of demographic factor.     

Danish and Norwegian hospital social workers’ cross-institutional work amidst inter-sectoral restructuring of health and social welfare

Starting in the 2000s, Denmark and Norway have undergone extensive restructuring of their health-related social benefit programmes, including how they are governed. Several reforms have sought to enhance inter-sectoral collaboration. Aiming at ensuring patients’ faster return to work, policy-makers have instituted economic incentives to both individuals and the health and welfare organisations who handle them. Through an institutional logics approach, this paper explores how hospital social workers in these countries are experiencing these changes. The ‘social’ part of post-treatment care and rehabilitation receives more attention in the Norwegian institutional set-up than in the Danish, and whilst challenges are experienced in both countries, in group interviews Danish social workers in particular express concerns about the implications of the accelerated return-to-work focus. In both countries, they report increasing difficulties in ‘making their way through’ the state-municipal bureaucracy. However, by drawing on the formal health knowledge derived from medical settings and the symbolic capital it bestows on them, they often manage to negotiate the work-and-welfare services, thereby transforming the social context for the patients.     

On probabilistic parametric inference

This paper formulates a theory of probabilistic parametric inference and explores the limits of its applicability. Unlike Bayesian statistical models, the system does not comprise prior probability distributions. Objectivity is imposed on the theory: a particular direct probability density should always result in the same posterior probability distribution. For calibrated posterior probability distributions it is possible to construct credible regions with posterior-probability content equal to the coverage of the regions, but the calibration is not generally preserved under marginalization. As an application of the theory, the paper also constructs a filter for linear Gauss–Markov stochastic processes with unspecified initial conditions.     

Multiple-class classification: Ordinal and categorical labels

We study multiple-class classification problems. Both ordinal and categorical labeled cases are discussed. The common approaches for multiple-class classification are built on binary classifiers, in which one-versus-one and one-versus-rest are typical approaches. When the number of classes is large, then these binary-classifier-based methods may suffer from either computational costs or the highly imbalanced sample sizes in their training stage. In order to alleviate the computational burden and the imbalanced training data issue in multiple-class classification problems, we propose a method that has competitive performance and retains the ease of model interpretation, which is essential for a prognostic/predictive model.     

Learning discrete decomposable graphical models via constraint optimization

Statistical model learning problems are traditionally solved using either heuristic greedy optimization or stochastic simulation, such as Markov chain Monte Carlo or simulated annealing. Recently, there has been an increasing interest in the use of combinatorial search methods, including those based on computational logic. Some of these methods are particularly attractive since they can also be successful in proving the global optimality of solutions, in contrast to stochastic algorithms that only guarantee optimality at the limit. Here we improve and generalize a recently introduced constraint-based method for learning undirected graphical models. The new method combines perfect elimination orderings with various strategies for solution pruning and offers a dramatic improvement both in terms of time and memory complexity. We also show that the method is capable of efficiently handling a more general class of models, called stratified/labeled graphical models, which have an astronomically larger model space.     

Use of thermobalancing therapy in ageing male with benign prostatic hyperplasia with a focus on etiology and pathophysiology

Introduction: We investigated if “thermobalancing” therapy (TT), using Dr Allen’s therapeutic device (DATD) in men with benign prostatic hyperplasia (BPH), can aid in understanding the etiology and pathophysiology of BPH.

Methods: We compared urinary and other parameters of BPH patients who received TT over 6 months (treatment group) with those of healthy volunteers who had not received the treatment (control group). Dynamics of symptoms and indicators in each group were evaluated in comparison with their data at the beginning and end of the study. Parameters were the International Prostate Symptom Score (IPSS) for urinary symptoms and quality of life (QoL), ultrasound measurement of prostate volume (PV) and uroflowmetry (maximum flow rate, Q_max). TT effectiveness was examined in 124 men with BPH and PV?<60?mL. We also investigated the data of five patients with BPH and PV?>60?mL.

Results: TT decreased urinary symptoms and PV, increased Q_max and improved QoL in men with BPH, PV?<60?mL, and in men with BPH, PV?>60?mL.

Conclusions: The present study demonstrated that TT is effective for BPH, suggesting that blood circulation plays a crucial role in its cause. The continuous heat exposure that does not exceed the normal body temperature terminates the trigger of BPH development, “micro-focus” of hypothermia, and the following spontaneous expansion of capillaries. TT could be considered to be a useful tool in BPH treatment.     

On MLEs of the parameters of a modified Weibull distribution based on record values

The modified Weibull distribution can be used quite effectively to model complex data from mechanical engineering or survival analysis studies that posses a monotonic or a bathtub-shape hazard rate. In this paper, we study the MLEs of the parameters of a modified Weibull distribution model in the presence of upper kth record values. The existence and uniqueness of the MLEs are proven in this case. Real data analysis is performed for illustrative purposes.     

The impact of testosterone replacement therapy on glycemic control,vascular function,and components of the metabolic syndrome in obese hypogonadal men with type 2 diabetes

Objective: This study set out to assess effects of testosterone replacement therapy (TRT) on parameters of metabolic syndrome and vascular function in obese hypogonadal males with type 2 diabetes mellitus (DM2).

Study design: Fifty-five obese hypogonadal diabetic males on oral hypoglycemic treatment were enrolled into this one-year, double-blind, randomized, placebo-controlled clinical study. Group T (n?=?28) was treated with testosterone undecanoate (1000?mg i.m. every 10?weeks) while group P (n?=?27) received placebo.

Methods: Anthropometrical and vascular measurements – flow-mediated dilatation (FMD) and intima media thickness (IMT) – biochemical and hormonal blood sample analyses were performed at the start of the study and after one year. Derived parameters (BMI, HOMA-IR, calculated free testosterone (cFT) and bioavailable testosterone (BT)) were calculated.

Results: TRT resulted in reduction of HOMA-IR by 4.64?±?4.25 (p?p?p?=?.005).

Conclusion: TRT normalized serum testosterone levels, improved glycemic control and endothelial function while exerting no ill effects on the study population.