Re‐framing the Analysis: A 3‐dimensional Perspective of Prisoners’ Children's Well‐being

This article highlights three dimensions to understanding children's well‐being during and after parental imprisonment which have not been fully explored in current research. A consideration of ‘time’ reveals the importance of children's past experiences and their anticipated futures. A focus on ‘space’ highlights the impact of new or altered environmental dynamics. A study of ‘agency’ illuminates how children cope within structural, material and social confines which intensify vulnerability and dependency. This integrated perspective reveals important differences in individual children's experiences and commonalities in broader systemic and social constraints on prisoners’ children. The paper analyses data from a prospective longitudinal study of 35 prisoners’ children during and after their (step) father's imprisonment to illustrate the arguments.     

A modified common factor model for modelling mortality jointly for both sexes

Journal of Population Research - There is an increasing attention on the joint modelling of multiple populations. Populations are related in several ways, such as neighbouring countries, females...     

Risk Analysis: Celebrating the Accomplishments and Embracing Ongoing Challenges

As part of the celebration of the 40th anniversary of the Society for Risk Analysis and Risk Analysis: An International Journal, this essay reviews the 10 most important accomplishments of risk analysis from 1980 to 2010, outlines major accomplishments in three major categories from 2011 to 2019, discusses how editors circulate authors’ accomplishments, and proposes 10 major risk-related challenges for 2020–2030. Authors conclude that the next decade will severely test the field of risk analysis.     

“一带一路”沿线国家设施联通对贸易利益的影响

以全球价值链（GVC）参与为视角，基于2005—2015年40个“一带一路”沿线国家与我国的增加值贸易数据，采用静态面板固定效应模型实证分析交通基础设施和通信基础设施对“一带一路”沿线国家贸易利益的影响。结果发现，加强交通和通信基础设施建设有利于提高一国出口中所包含的国内增加值，增进该国的贸易利益。作用机制研究表明，交通基础设施和通信基础设施都能够通过降低贸易成本促进贸易利益的提升，其中通信基础设施还能够通过提高贸易的时间效率对贸易利益产生积极影响。因此，“一带一路”沿线国家应以设施联通为依托，加强本国的交通和通信基础设施建设，把握参与国际生产分工的主动权，以实现共同发展繁荣。     

Inference and Decision Making for 21st-Century Drug Development and Approval

ABSTRACT

The cost and time of pharmaceutical drug development continue to grow at rates that many say are unsustainable. These trends have enormous impact on what treatments get to patients, when they get them and how they are used. The statistical framework for supporting decisions in regulated clinical development of new medicines has followed a traditional path of frequentist methodology. Trials using hypothesis tests of “no treatment effect” are done routinely, and the p-value < 0.05 is often the determinant of what constitutes a “successful” trial. Many drugs fail in clinical development, adding to the cost of new medicines, and some evidence points blame at the deficiencies of the frequentist paradigm. An unknown number effective medicines may have been abandoned because trials were declared “unsuccessful” due to a p-value exceeding 0.05. Recently, the Bayesian paradigm has shown utility in the clinical drug development process for its probability-based inference. We argue for a Bayesian approach that employs data from other trials as a “prior” for Phase 3 trials so that synthesized evidence across trials can be utilized to compute probability statements that are valuable for understanding the magnitude of treatment effect. Such a Bayesian paradigm provides a promising framework for improving statistical inference and regulatory decision making.     

储层岩石矿物成分对酸蚀裂缝导流能力的影响

储层岩石矿物成分是酸压改造效果影响因素之一。研究认为，在储层岩石矿物成分中易溶物的含量及分布方式决定了酸蚀裂缝导流能力大小，易溶蚀物的含量越多，岩石溶蚀速率越快。室内测试了不同溶蚀速率下的灰岩和白云岩的酸蚀裂缝导流能力，研究了岩石溶蚀速率、易溶蚀物含量对酸蚀裂缝导流能力的影响，对酸压工艺设计方案提出了指导性建议。研究结果表明，储层岩石溶蚀速率与酸蚀裂缝导流能力增加倍比存在抛物线关系，易溶蚀物占30%40% 时酸蚀裂缝导流能力保持较好。     

Racial Differences in Abused Older African American Males, Caucasian Males, and their Abusers

This study examined racial differences between mistreated and abused older African American and Caucasian men. The racial and gender differences of their perpetrators were also examined. Data from a single elder abuse provider agency in the State of Illinois were analyzed. Differences with respect to physical abuse, emotional abuse, physical neglect, deprivation, confinement, and financial exploitation were examined, as were demographic characteristics and limitations of victims and abusers.     

学习国外经验搞好土地规划

土地是财富之母,是人类社会赖以生存和发展的基础.随着我国经济建设的飞速发展和城市化进程的加快,城市建设用地与农业用地之间的矛盾日益尖锐,城市土地利用结构和布局不合理的问题也相当突出,这些都迫切要求进行科学合理的城市土地利用总体规划.城市土地利用总体规划是在一定时期内对城市范围内全部土地的综合利用所做的统筹安排和长远规划.它包括对城市建设用地与城市非建设用地的规划,当然同一级的农业区划也包括对这部分农业用地的规划.搞好城市土地利用总体规划意义重大,它能有效调节城市建设用地与农业用地之间的矛盾;有利于调整城市土地的结构和布局;也能加强城市土地供给的宏观调控,促进城市房地产业的健康发展.