Kullback-leibler information approach to the optimum measurement point for bayesian estimation

When an appropriate parametric model and a prior distribution of its parameters are given to describe clinical time courses of a dynamic biological process, Bayesian approaches allow us to estimate the entire profiles from a few or even a single observation per subject. The goodness of the estimation depends on the measurement points at which the observations were made. The number of measurement points per subject is generally limited to one or two. The limited measurement points have to be selected carefully. This paper proposes an approach to the selection of the optimum measurement point for Bayesian estimations of clinical time courses. The selection is made among given candidates, based on the goodness of estimation evaluated by the Kullback-Leibler information. This information measures the discrepancy of an estimated time course from the true one specified by a given appropriate model. The proposed approach is applied to a pharmacokinetic analysis, which is a typical clinical example where the selection is required. The results of the present study strongly suggest that the proposed approach is applicable to pharmacokinetic data and has a wide range of clinical applications.     

Marketisation policies in different contexts: Consequences for home‐care workers in Germany,Japan and Sweden

Market‐oriented restructurings of long‐term care policies contribute significantly to the aggravation of care workers’ situations. This article focuses on the effects of broader long‐term care policy developments on market‐oriented reforms. Germany, Japan and Sweden are three countries that have introduced market‐oriented reforms into home‐based care provision embedded in distinct long‐term care policy developments. Conceptually, this article draws on comparative research on care to define the institutional dimensions of long‐term care policies. Empirically, the research is based on policy analyses, as well as on national statistics and a comparative research project on home‐care workers in the aforementioned countries. The findings reveal the mediating impact of the extension and decline of long‐term public care support and the corresponding development of the care infrastructure on both the restructuring of care work and the assessments of the care workers themselves.     

A Note on Sample Size Determination for Akaike Information Criterion (AIC) Approach to Clinical Data Analysis

ABSTRACT

Because of its flexibility and usefulness, Akaike Information Criterion (AIC) has been widely used for clinical data analysis. In general, however, AIC is used without paying much attention to sample size. If sample sizes are not large enough, it is possible that the AIC approach does not lead us to the conclusions which we seek. This article focuses on the sample size determination for AIC approach to clinical data analysis. We consider a situation in which outcome variables are dichotomous and propose a method for sample size determination under this situation. The basic idea is also applicable to the situations in which outcome variables have more than two categories or outcome variables are continuous. We present simulation studies and an application to an actual clinical trial.     

How to Build an Intentional Android: Infants' Imitation of a Robot's Goal‐Directed Actions

This study examined whether young children are able to imitate a robot's goal‐directed actions. Children (24–35 months old) viewed videos showing a robot attempting to manipulate an object (e.g., putting beads inside a cup) but failing to achieve its goal (e.g., beads fell outside the cup). In 1 video, the robot made eye contact with a human before and after it failed the action. In another video, the robot did not make eye contact with the human adult. Only in the former condition did children “imitate” the robot's “intended” but unconsummated actions (e.g., putting beads inside a cup). When the robot did not make eye contact, children performed poorly, at the baseline level. These results suggest that human‐like gaze behaviors, not human‐like morphology, may play an important role in young children's imitation of a nonhuman agent's goal‐directed behaviors.     

Japanese Fathers of Preschoolers and Their Involvement in Child Care

We examine how relative resources, time availability, gender ideology, living arrangement, child‐care demand, and job satisfaction are associated with the levels of younger Japanese fathers’ involvement in child care for preschoolers. A theoretical model that includes these factors is tested using 1994 data collected from Japanese fathers and mothers with preschool children (N = 442 couples). We find that practical considerations such as fathers’ shorter work hours, mothers’ full‐time employment, fewer adults and more children in households, and younger ages of children are associated with higher levels of paternal involvement. Implications of these findings are discussed in light of attention to ways to encourage Japanese men's sharing of child‐care responsibilities with their wives.     

Popular Culture and Workplace Gendering among Varieties of Capitalism: Working Women and their Representation in Japanese Manga

Female empowerment is a prerequisite for a just and sustainable developed society. Being the most developed non‐western country, Japan offers an instructive window onto concerns about gender worldwide. Although overall gender equality is advancing in Japan, difficulties remain, especially in achieving equality in the workplace. We draw on theories of ontological commitment and the psychology of fiction to critically analyse the role of popular culture — in this case manga — in the reproduction of gender inequality in the Japanese workplace. We present examples of four of the most popular mainstream manga aimed at working men and women in Japan and show how women are depicted. We argue that the hyper‐mediated fictional realism of representative tropes generates an ontological commitment to characters and narratives among consumers that reinforces the reproduction of a culturally exceptionalist national political economic space, one of whose essential defining characteristics is a gendered workplace. Our research suggests important implications for researching the relationship between culture, in all its forms, and spatial variation in persistent institutional biases among varieties of capitalism.     

Food Access Among Elderly Japanese People

With a rapidly growing aging society, many elderly people in Japan have been facing difficulties of shopping in their daily life. Recently, this phenomenon has been found in urban areas, especially local cities. This growth of the aging society, combined with alterations to the food supply system, has caused food insecurity over a large area.The food insecurity may induce poor nutrition and disease in elderly people. The Ministries and local governments have taken measures for improving food access. Although NGOs, social organizations and the private sector manage social‐related businesses in many areas, they also rely on government funding. This paper proposes solutions for stakeholders to alleviate this considerable issue: (i) share research outcome, (ii) organize platforms for discussion, and (iii) strengthen community empowerment.     

"Involving interface": an extended mind theoretical approach to roboethics

In 2008 the authors held "Involving Interface," a lively interdisciplinary event focusing on issues of biological, sociocultural, and technological interfacing (see Acknowledgments). Inspired by discussions at this event, in this article, we further discuss the value of input from neuroscience for developing robots and machine interfaces, and the value of philosophy, the humanities, and the arts for identifying persistent links between human interfacing and broader ethical concerns. The importance of ongoing interdisciplinary debate and public communication on scientific and technical advances is also highlighted. Throughout, the authors explore the implications of the extended mind hypothesis for notions of moral accountability and robotics.