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211.
Social Indicators Research - Despite decreasing global poverty, feelings of increasing inequalities drive growing dissatisfaction with development outcomes. Inclusive development benefiting larger... 相似文献
212.
Christine Fletcher Stefan Driessen Hans Ulrich Burger Christoph Gerlinger Egbert Biesheuvel 《Pharmaceutical statistics》2013,12(6):333-336
The European Federation of Statisticians in the Pharmaceutical Industry (EFSPI) believes access to clinical trial data should be implemented in a way that supports good research, avoids misuse of such data, lies within the scope of the original informed consent and fully protects patient confidentiality. In principle, EFSPI supports responsible data sharing. EFSPI acknowledges it is in the interest of patients that their data are handled in a strictly confidential manner to avoid misuse under all possible circumstances. It is also in the interest of the altruistic nature of patients participating in trials that such data will be used for further development of science as much as possible applying good statistical principles. This paper summarises EFSPI's position on access to clinical trial data. The position was developed during the European Medicines Agency (EMA) advisory process and before the draft EMA policy on publication and access to clinical trial data was released for consultation; however, the EFSPI's position remains unchanged following the release of the draft policy. Finally, EFSPI supports a need for further guidance to be provided on important technical aspects relating to re‐analyses and additional analyses of clinical trial data, for example, multiplicity, meta‐analysis, subgroup analyses and publication bias. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
213.
The paper examines the behavior of a generalized version of the nonlinear IV unit root test proposed by Chang (2002) when the series’ errors exhibit nonstationary volatility. The leading case of such nonstationary volatility concerns structural breaks in the error variance. We show that the generalized test is not robust to variance changes in general, and illustrate the extent of the resulting size distortions in finite samples. More importantly, we show that pivotality is recovered when using Eicker-White heteroskedasticity-consistent standard errors. This contrasts with the case of Dickey-Fuller unit root tests, for which Eicker-White standard errors do not produce robustness and thus require computationally costly corrections such as the (wild) bootstrap or estimation of the so-called variance profile. The pivotal versions of the generalized IV tests – with or without the correct standard errors – do however have no power in $1/T$ -neighbourhoods of the null. We also study the validity of panel versions of the tests considered here. 相似文献
214.
Hodges Ron Caperchione Eugenio van Helden Jan Reichard Christoph Sorrentino Daniela 《Public Organization Review》2022,22(2):249-267
Public Organization Review - Immense uncertainty and the need for drastic interventions cause politicians to rely heavily on scientific advice for underpinning or legitimating their COVID-19... 相似文献
215.
AStA Advances in Statistical Analysis - Judging by its significant potential to affect the outcome of a game in one single action, the penalty kick is arguably the most important set piece in... 相似文献