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301.
Civil Registration and Vital Statistics (CRVS) Systems are playing increasing roles in national and global data infrastructure, facilitating the achievement of key developmental goals. The performance of CRVS systems in many developing countries including Nigeria is sub optimal and information on their structure and operations scanty. This paper characterizes the statutory, institutional, and operational elements and social contexts of the Nigerian CRVS System. It includes a context analysis of the system and a review of improvement strategies and interventions. The paper shows that the Nigerian CRVS System is built on viable statutory and institutional platforms—the constitutional enshrinement of: universal, compulsory and continuous civil registration and, a central registration institution—the National Population Commission (NPC). NPC has registration hierarchy and infrastructure deployed at every level of political administration and mechanisms for efficient coordination of registration and production of vital statistics on live-births, deaths and stillbirths amongst other vital events. The major weaknesses of the system include inadequate financing and deployment of registration facilities, conflicting statutes and institutional arrangements for the registration of key events like death and stillbirths. Other weaknesses include intra-organizational conflicts in resource allocation and weak ICT infrastructure within the NPC. These are compounded by overarching contextual issues namely registration unfriendly sociocultural norms, weak national data infrastructure, systemic corruption, poverty and undeveloped civic culture. Domestic initiatives and interventions to improve the system have focused on birth registration, while multilateral interventions have only made a modest impact on the system. Thus, holistic in-country improvement initiatives supported with robust interventions are imperative to overcome weaknesses in the Nigerian CRVS system. However fundamental improvements in CRVS systems in developing countries like Nigeria may likely only follow sustainable solutions to overarching contextual issues especially poor infrastructure, weak institutions, poverty and systemic corruption.  相似文献   
302.
本文旨在为王力著的《同源字典》拾遗补阙。有些字王力的著作虽已收录、考释,但这些字还有别的意义,尚可与另一些字构成另一对(或一组)同源字(即“同源词”)。本文依照“音近义通”的原则考释同源字。  相似文献   
303.
Inference of interaction networks represented by systems of differential equations is a challenging problem in many scientific disciplines. In the present article, we follow a semi-mechanistic modelling approach based on gradient matching. We investigate the extent to which key factors, including the kinetic model, statistical formulation and numerical methods, impact upon performance at network reconstruction. We emphasize general lessons for computational statisticians when faced with the challenge of model selection, and we assess the accuracy of various alternative paradigms, including recent widely applicable information criteria and different numerical procedures for approximating Bayes factors. We conduct the comparative evaluation with a novel inferential pipeline that systematically disambiguates confounding factors via an ANOVA scheme.  相似文献   
304.
We examine the effect of anomalous temperatures, rainfall levels, and monsoon timing on migration outcomes in Indonesia. Using panel data from the Indonesian Family Life Survey and high-resolution climate data, we assess whether intra- and inter-province moves are used as a response to climatic shocks. We evaluate the relative importance of temperature, rainfall, and monsoon timing for migration. Only temperature and monsoon timing have significant effects, and these do not operate in the direction commonly assumed. Estimated effects vary according to individuals’ gender, membership in a farm household, and location. We also analyze climate effects on sources of household income, which highlights the multi-phasic nature of household responses. Results undermine narratives of a uniform global migratory response to climate change and highlight the heterogeneous use of migration as a response to such changes. By extending previous research on environmentally induced migration in Indonesia, we also highlight the sensitivity of estimates to alternative climate and migration measures.  相似文献   
305.
Organizations are driven by continuous change. Global, socio-economic and technological megatrends – demographic changes and digitalization – are the reasons for transformation. Traditional organization forms are not in line with customers‘ need. Disruptive modes of development and innovations have been intensively discussed elsewhere. The topic of disruptive organization have not been discussed towards internal and external customer relations, although of high relevance. 129 Managers answered on communication ways and the purpose of upcoming meaning for the working place/office. Two new models and five concrete recommendations have been established for upcoming future organization.  相似文献   
306.
以广州市边缘区为典型案例,深入剖析了大城市边缘区人居环境问题,包括过度依赖外资、生态环境隐患、建设用地无序扩张、违章建筑、房地产开发失衡与基础设施配套滞后、传统文化衰落等,并针对性地提出优化调控措施:促进产业结构改造与升级,完善基础设施和公共服务设施配套,实施生态环境保护与综合整治,加强房地产开发的政府引导,推进边缘区管理体制改革;完善边缘区规划体系。  相似文献   
307.
Analysis of massive datasets is challenging owing to limitations of computer primary memory. Composite quantile regression (CQR) is a robust and efficient estimation method. In this paper, we extend CQR to massive datasets and propose a divide-and-conquer CQR method. The basic idea is to split the entire dataset into several blocks, applying the CQR method for data in each block, and finally combining these regression results via weighted average. The proposed approach significantly reduces the required amount of primary memory, and the resulting estimate will be as efficient as if the entire data set is analysed simultaneously. Moreover, to improve the efficiency of CQR, we propose a weighted CQR estimation approach. To achieve sparsity with high-dimensional covariates, we develop a variable selection procedure to select significant parametric components and prove the method possessing the oracle property. Both simulations and data analysis are conducted to illustrate the finite sample performance of the proposed methods.  相似文献   
308.
Competing risks occur in a time-to-event analysis in which a patient can experience one of several types of events. Traditional methods for handling competing risks data presuppose one censoring process, which is assumed to be independent. In a controlled clinical trial, censoring can occur for several reasons: some independent, others dependent. We propose an estimator of the cumulative incidence function in the presence of both independent and dependent censoring mechanisms. We rely on semi-parametric theory to derive an augmented inverse probability of censoring weighted (AIPCW) estimator. We demonstrate the efficiency gained when using the AIPCW estimator compared to a non-augmented estimator via simulations. We then apply our method to evaluate the safety and efficacy of three anti-HIV regimens in a randomized trial conducted by the AIDS Clinical Trial Group, ACTG A5095.  相似文献   
309.
For survival endpoints in subgroup selection, a score conversion model is often used to convert the set of biomarkers for each patient into a univariate score and using the median of the univariate scores to divide the patients into biomarker‐positive and biomarker‐negative subgroups. However, this may lead to bias in patient subgroup identification regarding the 2 issues: (1) treatment is equally effective for all patients and/or there is no subgroup difference; (2) the median value of the univariate scores as a cutoff may be inappropriate if the sizes of the 2 subgroups are differ substantially. We utilize a univariate composite score method to convert the set of patient's candidate biomarkers to a univariate response score. We propose applying the likelihood ratio test (LRT) to assess homogeneity of the sampled patients to address the first issue. In the context of identification of the subgroup of responders in adaptive design to demonstrate improvement of treatment efficacy (adaptive power), we suggest that subgroup selection is carried out if the LRT is significant. For the second issue, we utilize a likelihood‐based change‐point algorithm to find an optimal cutoff. Our simulation study shows that type I error generally is controlled, while the overall adaptive power to detect treatment effects sacrifices approximately 4.5% for the simulation designs considered by performing the LRT; furthermore, the change‐point algorithm outperforms the median cutoff considerably when the subgroup sizes differ substantially.  相似文献   
310.
The use of Bayesian nonparametrics models has increased rapidly over the last few decades driven by increasing computational power and the development of efficient Markov chain Monte Carlo algorithms. We review some applications of these models in economic applications including: volatility modelling (using both stochastic volatility models and GARCH-type models) with Dirichlet process mixture models, uses in portfolio allocation problems, long memory models with flexible forms of time-dependence, flexible extension of the dynamic Nelson-Siegel model for interest rate yields and multivariate time series models used in macroeconometrics.  相似文献   
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