Investigating the Effects of Pre‐school Provision: Using Mixed Methods in the EPPE Research

The Effective Provision of Pre‐school Education (EPPE) project is a longitudinal study of young children between the ages of 3 and 7 years. Research began in 1997 and both quantitative and qualitative methods were used to explore the effects of pre‐school education on children’s attainment and social/behavioural development at entry to school, and of any continuing effects on such outcomes at the end of Key Stage 1 (age 7). The sample included over 3,000 children and 141 pre‐school centres drawn from six different types of providers. In addition, a home sample of children who had not attended a pre‐school centre was included. In order to identify the processes that might influence centre effectiveness, observational data were collected and centre managers interviewed. In‐depth case studies of 12 more effective centres were used to explore and illuminate the processes, particularly in relation to pedagogy, associated with better child outcomes. A mixed method approach was adopted to simultaneously answer both confirmatory and exploratory questions, to support user engagement and provide triangulation. The paper argues that the mixed method approach supported the development of stronger research inferences.     

Predicting the Probability that a Chemical Causes Steatosis Using Adverse Outcome Pathway Bayesian Networks (AOPBNs)

Adverse outcome pathway Bayesian networks (AOPBNs) are a promising avenue for developing predictive toxicology and risk assessment tools based on adverse outcome pathways (AOPs). Here, we describe a process for developing AOPBNs. AOPBNs use causal networks and Bayesian statistics to integrate evidence across key events. In this article, we use our AOPBN to predict the occurrence of steatosis under different chemical exposures. Since it is an expert-driven model, we use external data (i.e., data not used for modeling) from the literature to validate predictions of the AOPBN model. The AOPBN accurately predicts steatosis for the chemicals from our external data. In addition, we demonstrate how end users can utilize the model to simulate the confidence (based on posterior probability) associated with predicting steatosis. We demonstrate how the network topology impacts predictions across the AOPBN, and how the AOPBN helps us identify the most informative key events that should be monitored for predicting steatosis. We close with a discussion of how the model can be used to predict potential effects of mixtures and how to model susceptible populations (e.g., where a mutation or stressor may change the conditional probability tables in the AOPBN). Using this approach for developing expert AOPBNs will facilitate the prediction of chemical toxicity, facilitate the identification of assay batteries, and greatly improve chemical hazard screening strategies.     

The evolutionary anthropology of political leadership

Existing approaches within leadership studies often share a bias towards industrialized societies and lack broader cross-cultural and ethological reference. Meanwhile, cross-cultural and evolutionary approaches within anthropology are actively working to unify research on leadership and followership across the biological and social sciences. This review provides a novel and thorough view of political leadership as investigated by evolutionary anthropologists and highlights the benefits of incorporating findings from the evolutionary social sciences into leadership studies generally. We introduce the anthropological approach to leadership; describe evolutionary anthropology, its subdisciplines (including primatology, paleoanthropology, paleogenetics, human behavioral ecology, and gene-culture coevolution), and its complementary disciplines (particularly evolutionary psychology); review leadership and hierarchy in nonhumans, including our extinct hominid ancestors; review female leadership and sex-differences; and, primarily, discuss the relationships between evolution, ecology, and culture as they relate to the observed patterns of political leadership and followership across human societies. Through evolutionary anthropology's diverse toolkit, a deeper insight into the evolution and cross-cultural patterning of leadership is realized.     

New dawn or end of labour?: from South Africa’s East Rand to Ekurhuleni

ABSTRACT

The question raised in this article is whether the key role played under apartheid by labour in the transition to democracy can be revived in the struggle against the persistent and deepening inequality of the post-apartheid period. We argue that the transition to a neoliberal state in the post-apartheid period has fragmented workers and weakened their capacity to build sustainable workplace organization. However, in spite of this, we identify the emergence of collective action and organization amongst these precarious workers. We show how in response to the degeneration of their traditional organizations, these workers are rebuilding worker organization still very much inscribed in the organizational traditions built on the East Rand over 40 years ago. We challenge the pessimistic ‘end of labour’ thesis that suggests that the informalization of employment has made collective organization impossible.