We and others have previously shown that testosterone replacement therapy (TRT) results in sustained weight loss in the majority of middle-aged hypogonadal men. Previously, however, a small proportion failed to lose at least 5% of their baseline weight. The reason for this is not yet understood. In the present study, we sought to identify early indicators that may predict successful long-term weight loss, defined as a reduction of at least 5% of total body weight relative to baseline weight (T0), in men with hypogonadism undergoing TRT. Eight parameters measured were assessed as potential predictors of sustained weight loss: loss of 3% or more of baseline weight after 1 year of TU treatment, severe hypogonadism, BMI, waist circumference, International Prostate Symptom Score (IPSS), glycated hemoglobin (HbA1C), age and use of vardenafil. Among the eight measured parameters, three factors were significantly associated with sustained weight loss over the entire period of TU treatment: (1) a loss of 3% of the baseline body weight after 1 year of TRT; (2) baseline BMI over 30; and (3) a waist circumference >102?cm. Age was not a predictor of weight loss. 相似文献
There are numerous examples of small-scale hydrogeomorphic manipulations within urban ecosystems. These modifications are
motivated both by a need to handle storm drainage and by a human desire for aquatic ecosystems as places for recreation and
aesthetics. In the Phoenix Arizona metropolitan area, two examples of these local modifications are artificial lakes and stormwater
retention basins. Although lakes are not a natural feature of Sonoran Desert ecosystems, numerous artificial lakes are evident
in the region. Retention basins are a common landscaping practice for preventing damage from rare but potentially large storm
events. Here we attempt to quantify the heretofore unknown number and extent of these designed aquatic ecosystems and consider
their potential impact on hydrologic landscape connectivity and regional nitrogen (N) removal. For lakes, we found that official
GIS layers from local and state agencies had significant misclassifications and omissions. We used two published GIS datasets
and state impoundment-permit information to determine the number, areal extent, and water source for artificial lakes. We
discovered that there are 908–1,390 lakes in the Phoenix area, with the number varying according to level of aggregation.
There are no existing GIS data on retention basins, so we employed drywell-permit data to estimate that there may be 10,000
retention basins in the region. Basic data on N stocks in these ecosystems are discussed within the context of the regional
N budget. Accurate data on the extent and distribution of these designed ecosystems will be vital for water-resources planning
and stormwater management. 相似文献
ABSTRACTThe initiation of political reforms and a peace process in Myanmar has fundamentally altered the conditions for Burmese diasporic politics, and diaspora groups that have mobilized in Myanmar’s neighbouring countries are beginning to return. This article explores how return to Myanmar is debated within the Burmese women’s movement, a significant and internationally renowned segment of the Burmese diaspora. Does return represent the fulfilment of diasporic dreams; a pragmatic choice in response to less than ideal circumstances; or a threat to the very identity and the feminist politics of the women’s movement? Contrasting these competing perspectives, the analysis offers insights into the ongoing negotiations and difficult choices involved in return, and reveals the process of return as highly conflictual and contentious. In particular, the analysis sheds light on the gendered dimensions of diaspora activism and return, demonstrating how opportunities for women's activism are challenged, debated and reshaped in relation to return. 相似文献
Drawing on 26 months of field research in El Salvador during the civil war, I analyze some ethical challenges that confront
field researchers working in conflict zones. After briefly summarizing the purpose and general methodology of my research,
I discuss in detail the research procedures I followed to implement the “do no harm” ethic of empirical research. I first
analyze the particular conditions of the Salvadoran civil war during the period of research. I then discuss the procedures
meant to ensure that my interviews with people took place with their fully informed consent—what I understood that to mean
and how I implemented it. I then turn to the procedures whereby the anonymity of those interviewed and the confidentiality
of the data gathered were ensured to the extent possible. Throughout I discuss particular ethical dilemmas that I confronted,
including issues of self-presentation and mistaken identity, the emotional challenges of field work in highly polarized settings
(which if not well understood may lead to lapse in judgment), and my evolving questions concerning the researcher role and
its limitations. I also discuss the dilemmas that arise in the dissemination of research findings and the repatriation of
data.
Contemporary supervision practice has increasingly involved tasks previously associated with line management; this has been uncomfortable and unresolved for both supervisors and supervisees. Context, individual preference and circumstance can drive the relationship more into surveillance or more into support, and each will have important implications for practice. This article argues for a balance between monitoring and mentoring, both are crucial for effective supervision to occur. Supervisors need to know the boundaries of their delegated task, given that supervision can be the intervention of choice for any number of organizational difficulties. However they also need to integrate the leadership and critical appraisal tasks required, commencing supervision relationships with these components being transparent and clear, such that all participants can meet their obligations to practice competently, ethically and in the clients' interests. The systemic model provides an effective framework to conceptualise and intervene in relation to the various stakeholders, relationships, service systems and political context in which arrangements for supervision are negotiated. 相似文献
While much of the literature on gender focuses on role models, this paper extends the understanding of gendered professional identification processes by exploring these processes through the lenses of idealization and admiration. Using the method of discourse analysis to analyse MBA students' accounts of people with whom they identify, this paper explores discourses of idealization, defined as aggrandizing a person, and of admiration, which means discussing positive as well as negative and neutral characteristics of a person. It is shown, first, that most male and female MBA students idealized the self‐made ‘authentic’ CEO or founder of an organization and, second, that women mainly admired other women through naming their positive, neutral and negative attributes. The paper thereby adds to understanding of how gendered identification processes are structured by idealization and admiration. 相似文献
Fear of childbirth negatively affects women during pregnancy and after birth.
Aim
To summarise the findings of published studies regarding possible causes/predisposing factors and outcomes of fear of childbirth for childbearing women.
Design
A systematic review, searching five databases in March 2015 for studies on causes/predisposing factors and outcomes of fear of childbirth, as measured during pregnancy and postpartum. Quality of included studies was assessed independently by pairs of authors. Data were extracted independently by reviewer pairs and described in a narrative analysis.
Findings
Cross-sectional, register-based and case-control studies were included (n = 21). Causes were grouped into population characteristics, mood-related aspects, and pregnancy and birth-related aspects. Outcomes were defined as mood-related or pregnancy and birth-related aspects. Differing definitions of fear of childbirth were found and meta-analysis could only be performed on parity, in a few studies.
Conclusions
Stress, anxiety, depression and lack of social support are associated with fear during pregnancy. Need for psychiatric care and presence of traumatic stress symptoms are reported outcomes together with prolonged labour, longer labours, use of epidural and obstetric complications. Nulliparous and parous women have similar levels of fear but for different reasons. Since the strongest predictor for fear in parous women is a previous negative birth experience or operative birth, we suggest it is important to distinguish between fear of childbirth and fear after birth. Findings demonstrate the need for creating woman-centred birthing environments where women can feel free and secure with low risk of negative or traumatic birth experiences and consequent fear. 相似文献
The increasing complexity of the business world has led to growing demands for companies to provide information about their financial performance, their corporate governance and their contribution to developing sustainability. In addition, there are increasing needs for investors to obtain more information about the value creation process since financial reporting systems account imperfectly for most of intangible assets generated by companies. In this context, this article aims to determine if integrated reporting does effectively achieve the objective of reducing the information asymmetry. To answer this research question, a qualitative content analysis was conducted of the IR disclosed by the French companies in the period of 2013–16. The study reveals that information asymmetry is not reduced since companies mention only some capitals as inputs to their value creation process while almost entirely excluding natural capital. Moreover, companies disclose only positive information mainly about their financial capital, without mentioning any destruction of capital, especially not the natural one. Finally, from our findings, signals disclosed by these companies can be classified in three categories: intent signals composed of information about social and relational capital; camouflage signals composed of information about the reduction of the pollution without mentioning the pollution itself and need signals composed of information about dividends encouraging investors to maintain their financial support.