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281.
Fabien Gagnon Mathieu Courchesne Benoît Lévesque Pierre Ayotte Jean‐Marc Leclerc Jean‐Claude Belles‐Isles Claude Prévost Jean‐Claude Dessau 《Risk analysis》2008,28(5):1221-1230
The present study was aimed at assessing the health consequences of the presence of radon in Quebec homes and the possible impact of various screening programs on lung cancer mortality. Lung cancer risk due to this radioactive gas was estimated according to the cancer risk model developed by the Sixth Committee on Biological Effects of Ionizing Radiations. Objective data on residential radon exposure, population mobility, and tobacco use in the study population were integrated into a Monte‐Carlo‐type model. Participation rates to radon screening programs were estimated from published data. According to the model used, approximately 10% of deaths due to lung cancer are attributable to residential radon exposure on a yearly basis in Quebec. In the long term, the promotion of a universal screening program would prevent less than one death/year on a province‐wide scale (0.8 case; IC 99%: –3.6 to 5.2 cases/year), for an overall reduction of 0.19% in radon‐related mortality. Reductions in mortality due to radon by (1) the implementation of a targeted screening program in the region with the highest concentrations, (2) the promotion of screening on a local basis with financial support, or (3) the realization of systematic investigations in primary and secondary schools would increase to 1%, 14%, and 16.4%, respectively, in the each of the populations targeted by these scenarios. Other than the battle against tobacco use, radon screening in public buildings thus currently appears as the most promising screening policy for reducing radon‐related lung cancer. 相似文献
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Robert H. Lyles Cynthia M. Lyles & Douglas J. Taylor 《Journal of the Royal Statistical Society. Series C, Applied statistics》2000,49(4):485-497
Objectives in many longitudinal studies of individuals infected with the human immunodeficiency virus (HIV) include the estimation of population average trajectories of HIV ribonucleic acid (RNA) over time and tests for differences in trajectory across subgroups. Special features that are often inherent in the underlying data include a tendency for some HIV RNA levels to be below an assay detection limit, and for individuals with high initial levels or high ranges of change to drop out of the study early because of illness or death. We develop a likelihood for the observed data that incorporates both of these features. Informative drop-outs are handled by means of an approach previously published by Schluchter. Using data from the HIV Epidemiology Research Study, we implement a maximum likelihood procedure to estimate initial HIV RNA levels and slopes within a population, compare these parameters across subgroups of HIV-infected women and illustrate the importance of appropriate treatment of left censoring and informative drop-outs. We also assess model assumptions and consider the prediction of random intercepts and slopes in this setting. The results suggest that marked bias in estimates of fixed effects, variance components and standard errors in the analysis of HIV RNA data might be avoided by the use of methods like those illustrated. 相似文献
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Elizabeth M. Timberlake D.S.W. 《Child and Adolescent Social Work Journal》1990,7(3):199-216
This comparative study of 60 parents' and teachers' views of how elementary school children cope with their own mild physical differences and with current psychosocial development and academic tasks in mainstream classrooms identified statistically significant differences in use of defensive-adaptive imagery and psychosocial functioning between children experiencing academic success and failure. 相似文献
287.
This article describes a multilevel theoretical framework that examines the multiple causes of corporate social responsibility (CSR) reporting in the social environment of business. We argue that substantive and/or symbolic reporting flows from individual‐, aggregate‐, organizational‐, and institution‐level phenomena, and is thus a complex outcome of CSR and corporate social performance (CSP). Theoretical lenses range from reinforcement theory at the microlevel to legitimacy and stakeholder theories at the macrolevel, and include a discussion of the emergence of lower‐level CSR‐relevant characteristics to higher level constructs. Our goal is to clarify how this behavior develops from microlevel, mesolevel, and macrolevel processes with a view toward assisting corporations to better enact CSR reporting, and their stakeholders to effectively promote substantive reporting behavior. 相似文献
288.
Kim L. Gratz Elizabeth J. Kiel Robert D. Latzman Sarah A. Moore T. David Elkin Gail C. Megason Matthew T. Tull 《Infancy》2015,20(3):306-338
Despite the developmental and clinical relevance of this area of inquiry, no studies have examined the interrelations of trait vulnerabilities in the affective, behavioral, and interpersonal domains between mothers and their infants. Thus, this study examined the interrelations of three trait vulnerabilities (i.e., negative affective intensity, impulsivity, and insecure attachment) between mothers and their 12‐ to 23‐month‐old infants, focusing in particular on the unique and interactive influence of these maternal trait vulnerabilities on the expression of and precursors to these traits in their infants. Mother–infant dyads (N = 101) completed several laboratory procedures, and mothers reported on their own and their infants' expressions of the trait vulnerabilities of interest. Findings from this study provide preliminary evidence for intergenerational relations between these traits and suggest that it is the confluence of trait vulnerabilities in mothers that relates to the early expression of some of these traits in infants. 相似文献
289.
Closing The Gap between Two Countries: Feasibility of Dissemination Of An Evidence‐Based Parenting Intervention in México
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290.
Amanda Howard Tamara Blakemore Lou Johnston Darleen Taylor Rani Dibley 《Disability & Society》2015,30(9):1365-1381
The National Disability Insurance Scheme (NDIS) is one of the most significant initiatives in Australian social policy history. Its complexity has been compounded by a fast-paced introduction and ongoing refinement throughout the initial trial phase. Parents and carers of very young disabled children face particular challenges accessing and navigating NDIS systems. This article presents findings from a mixed-method pilot study examining the perspectives of parents and carers of disabled children in one NDIS trial site – the Hunter Region of New South Wales. The research highlights a number of policy assumptions potentially impacting on NDIS take up for young disabled children and their families in regional contexts. Based on research findings a number of policy suggestions and improvements for disabled children and their families entering the NDIS and other individualised funding schemes are outlined. 相似文献