Role of physical activity in tumor patients and possible underlying mechanisms

A growing knowledge regarding the influence of exercise on adverse physiologic outcomes associated with cancer and its treatment exists. Aside from its effects on psychological behavior, quality of life, and cancer-related fatigue, physical exercise can target physical and cardio-respiratory fitness, insulin regulation and metabolic syndrome, body weight and composition, and immune function in tumor patients. The increasing number of study results for different cancer types, which prove the positive influences of physical activity in cancer patients, changed the contradictory opinions which existed until the end of the last century. Although an increasing number of studies showing the positive effects of physical activity and more specifically of endurance and resistance training in cancer patients have been published, the underlying mechanisms are mostly unknown. Thus, we summarized the current knowledge of the effects of physical activity and specific training in different tumor entities with specific respect to the possible underlying mechanisms. Especially, the association between physical activity and (1) the improvement of fatigue and the role of free radicals in this process, (2) the counterbalance of tumor-induced cachexia, (3) the improvement of the immune system for supportive tumor treatment, and (4) the possible role of epigenetic modulation against tumor and tumor treatment-dependent adverse physiologic outcomes is focused.     

A 1,408 km bicycle tour with prostate cancer patients—results of a pilot study

Negative psychological and physical effects of prostate cancer and its medical treatment may persist many years after diagnosis. The influence of a long cycling tour on rehabilitative or health-related effects with prostate cancer patients has not yet been studied. In practice, physicians and therapists rarely recommend cycling to prostate cancer. In May 2010, eight prostate cancer patients rode their bikes for over 1,408 km from Cologne to Marseille within 5 weeks. Endurance test, blood examinations (prostate-specific antigen (PSA), total testosterone, interleukin-6, oxidative stress, and antioxidant capacity) and quality of life questionnaires were completed before and after the tour. All eight subjects reached Marseille. Significant improvements could be observed in physical performance and certain quality of life scores (p?=?0.008), as well as a reduction of total testosterone (p?=?0.19). PSA levels did not change. This pilot study suggests that long bicycle tours with prostate cancer patients are feasible. Due to the missing control group and the small sample size, the results of this pilot study are limited.     

Evaluations and Future Plans After Casual Sexual Experiences: Differences Across Partner Type

Casual sexual relationships and experiences (CSREs) are common among emerging adults, and their diversity may contribute to variability in their associations with mental health and future romantic relationship development. The present research used multiple regression analyses to examine how CSRE type (casual dating, friends with benefits [FWB], or booty call/one-night stand) is associated with short-term outcomes of these experiences, including positive and negative evaluations, plans to start a romantic relationship with a CSRE partner, and general plans for future CSREs. College students and non-college-attending emerging adults (N = 192, 80% female, mean age = 22.09 years) reported on recent sexual encounters through daily diaries collected around an alcohol consumption holiday. Individuals with casual dating partners evaluated their experiences more positively and/or less negatively than individuals with booty calls/one-night stands; these associations were moderated by gender and sexual behavior type. Individuals with casual dating partners were more oriented toward pursuing a romantic relationship with their partners than individuals with FWB or booty calls/one-night stands. However, no association was found between CSRE type and plans for future CSREs in general. Results highlight the diversity of CSREs and suggest that casual dating may be more rewarding than FWB and booty calls/one-night stands, particularly for women.     

College students’ use of transportation networking companies: An opportunity to decrease substance-impaired driving

Abstract

Objective: To examine the use of transportation networking companies (TNCs) (eg, Uber) among substance-using students in rural and urban college settings. Participants: Students at two large state universities were randomly selected and screened for substance use. Participants reported use of TNCs generally and after substance use and whether TNC use was on or near campus or in other environments. Methods: Data were evaluated using chi-square test, t-tests, and Fisher’s exact tests. Results: Most (85%) participants (n?=?99, 61% response rate) had used a TNC. Among students who used TNCs on/near campus, 98% of rural students used them after substance use compared to 85% of urban students (p?=?.037). We did not detect differences in TNC use by gender or age. Conclusions: Results indicate that TNC use is common after college student substance use and may play a particularly important role in preventing impaired driving for rural campuses where existing transportation options are limited.     

Self-Regulatory Driving Behaviors: Gender and Transportation Support Effects

This study examined the relationship between transportation support and self-regulatory driving behaviors of 566 community-dwelling older adults living in retirement communities, with a focus on gender differences. The results of logistic regression analysis showed that older women were more likely to avoid driving at night or on the highway than their male counterparts. Transportation support from peer friends was found to increase the likelihood of self-regulatory driving behaviors. The findings of this study imply that transportation policy and driving safety programs for older adults need to be developed, considering available transportation alternatives and gender differences in driving behaviors.     

Still connecting the dots: An investigation into infants' attentional bias to threat using an eye-tracking task

An attentional bias toward threat has been theorized to be a normative aspect of infants' threat and safety learning, and an indicator of risk for internalizing psychopathology in older populations. To date, only four studies have examined this bias using the dot-probe task in infancy and the findings are mixed. We extended the literature by examining patterns of attention to threat in a culturally and linguistically diverse sample of infants aged 5–11 months old (N = 151) using all measures previously employed in the infant dot-probe literature. Given that an attentional bias toward threat is associated with higher risk of developing anxiety disorders later in life, we also examined how negative affect—an early correlate of later anxiety disorders—is related to attentional bias toward threat in infancy. This study was the first to use a consistent measure of negative affect across the whole sample. An eye-tracking dot-probe task was used to examine attentional bias toward threat (i.e., angry faces) relative to positive (i.e., happy faces) stimuli. Results showed that an attention bias to threat was not characteristic of infants at this age, and negative affect did not moderate the putative relationship between attention and emotional faces (angry, happy). These findings therefore suggest that attention biases to socio-emotional threat may not have emerged by 11 months old.     

A new useful three-parameter extension of the exponential distribution

A three-parameter extension of the exponential distribution is introduced and studied in this paper. The new distribution is quite flexible and can be used effectively in modelling survival data, reliability problems, fatigue life studies and hydrological data. It can have constant, decreasing, increasing, upside-down bathtub (unimodal), bathtub-shaped and decreasing–increasing–decreasing hazard rate functions. We provide a comprehensive account of the mathematical properties of the new distribution and various structural quantities are derived. We discuss maximum likelihood estimation of the model parameters for complete sample and for censored sample. An empirical application of the new model to real data is presented for illustrative purposes. We hope that the new distribution will serve as an alternative model to other models available in the literature for modelling real data in many areas.     

Counting the Population or Describing Society? A Comparison of English and Welsh and French Censuses

Data collected at household level in censuses are used for a wide range of purposes including practical planning and academic analysis of changing social conditions. Comparability is a core demographic value, and to understand the limits of the comparability of census data across time and space, it is important to recognise if, how and why, concepts and definitions change between censuses. This paper examines definitions of the household in censuses in England and Wales (E&W) and France from 1960 to 2012 in order to investigate how census definitions have changed and to examine the drivers of such changes. Two research methods were used: (1) longitudinal analyses of census documentation since the 1960s and (2) in-depth interviews with key informants oriented around respondents’ roles in the collection and/or use of household data from censuses and surveys. We identify two contrasting national approaches to the data collection exercise that is called a census, which reflect political and institutional differences. These differences call into question the comparability of some aspects of census data across national boundaries, despite increased harmonisation of approaches to data collection. By comparing the evolution of the definitions of the “household” in censuses, we develop insight into the diversity of the priorities of census commissioners and designers, and consider the broader implications of this for producing comparable data.     

Factors contributing to the perpetration of workplace incivility: the importance of organizational aspects and experiencing incivility from others

In recent years a growing amount of research has been conducted in the area of workplace incivility. Whereas many studies have focused on the victims and the consequences of incivility, little attention has been paid to the perpetrators and antecedents of workplace incivility. This study aims to identify possible antecedents of workplace incivility, by investigating organizational aspects as well as the possibility that being the target of incivility from co-workers and supervisors could induce incivility. A total of 512 employees (378 women and 133 men) in the school sector in a Swedish municipality completed an online questionnaire. Overall, the results of structural equation modelling analyses showed that organizational variables were related to the perpetration of incivility. A direct relationship was found between being uncivil and organizational change, job insecurity, low social support from co-workers and high job demands. However, the strongest relationship was found between experienced incivility from co-workers and instigated incivility. This could be reflecting a climate or culture of incivility in the organization, and carry implications for future practice in interventions against workplace incivility. The results indicate the importance of focusing on the perspective of the instigator to gain knowledge about the process of workplace incivility.     

The Read Feed: Reviews

ABSTRACT

Heylicken Moreno reviews Linked Data for Libraries, Archives and Museums: How to Clean, Link and Publish Your Metadata; Trina Boykin Nolen reviews Metaliteracy: Reinventing Information Literacy to Empower Learners; Stephanie Rosenblatt reviews Records and Information Management.