Analyzing Binomial Data in a Split-Plot Design: Classical Approach or Modern Techniques?

Modeling data that are non-normally distributed with random effects is the major challenge in analyzing binomial data in split-plot designs. Seven methods for analyzing such data using mixed, generalized linear, or generalized linear mixed models are compared for the size and power of the tests. This study shows that analyzing random effects properly is more important than adjusting the analysis for non-normality. Methods based on mixed and generalized linear mixed models hold Type I error rates better than generalized linear models. Mixed model methods tend to have higher power than generalized linear mixed models when the sample size is small.     

On asymptotic distribution of the test statistic for the mean of the non-isotropic principal component

In this paper, the authors derived the large sample distribution of the t statistic based upon the observations on the first principal component instead of the original variables. It is shown that the above statistic is distributed asymptotically as Student's t distribution.     

Uniform Design for Experiments with Mixtures

The goal of uniform mixture design is to scatter the design points in the experimental region uniformly. The commonly used criteria, such as mean square distance, are based on the Euclidean distance. Based on the Lee distance, a new criterion is proposed in this article. And an algorithm, called NTLBG, is also proposed to refine the randomly generated design for the experimental design with mixtures. Some examples show that the design generated by the NTLBG algorithm has a lower criteria value.     

A Simple Approximate Procedure for Constructing Binomial and Poisson Tolerance Intervals

The problems of constructing tolerance intervals for the binomial and Poisson distributions are considered. Closed-form approximate equal-tailed tolerance intervals (that control percentages in both tails) are proposed for both distributions. Exact coverage probabilities and expected widths are evaluated for the proposed equal-tailed tolerance intervals and the existing intervals. Furthermore, an adjustment to the nominal confidence level is suggested so that an equal-tailed tolerance interval can be used as a tolerance interval which includes a specified proportion of the population, but does not necessarily control percentages in both tails. Comparison of such coverage-adjusted tolerance intervals with respect to coverage probabilities and expected widths indicates that the closed-form approximate tolerance intervals are comparable with others, and less conservative, with minimum coverage probabilities close to the nominal level in most cases. The approximate tolerance intervals are simple and easy to compute using a calculator, and they can be recommended for practical applications. The methods are illustrated using two practical examples.     

Empirical Likelihood Inference for the Parameter in Additive Partially Linear EV Models

In this article, we consider empirical likelihood inference for the parameter in the additive partially linear models when the linear covariate is measured with error. By correcting for attenuation, a corrected-attenuation empirical log-likelihood ratio statistic for the unknown parameter β, which is of primary interest, is suggested. We show that the proposed statistic is asymptotically standard chi-square distribution without requiring the undersmoothing of the nonparametric components, and hence it can be directly used to construct the confidence region for the parameter β. Some simulations indicate that, in terms of comparison between coverage probabilities and average lengths of the confidence intervals, the proposed method performs better than the profile-based least-squares method. We also give the maximum empirical likelihood estimator (MELE) for the unknown parameter β, and prove the MELE is asymptotically normal under some mild conditions.     

Estimation Bias in Complete-Case Analysis in Crossover Studies with Missing Data

Crossover designs are used often in clinical trials. It is not uncommon that subjects discontinue before completing all treatment periods in a crossover study. Despite availability of statistical methodologies utilizing all available data and software for obtaining valid inferences under the assumption of missing at random (MAR), naïve approaches, such as the complete case (CC) analysis, which is only valid with a strong assumption of missing completely at random are still widely used in practice. In this article, we obtain the analytical form of the estimation bias of treatment effects with CC for linear mixed models. We use simulation studies to examine the inflation of Type I error and efficiency loss in the inferences with CC under MAR. Invalidity and inefficiency of two other commonly used approaches for defining analyzed data in the presence of missing data, including data from at least two periods in three period crossover and available cases for a specific comparison of interest, are also demonstrated through simulation studies.     

Testing for the Equality of Two Autoregressive Functions Using Quasi-Residuals

This article discusses the problem of testing the equality of two nonparametric autoregressive functions against one-sided alternatives. The heteroscedastic errors and stationary densities of the two independent strong mixing strictly stationary time series can be possibly different. The article adapts the idea of using sum of quasi-residuals to construct the test and derives its asymptotic null distributions. The article also shows that the test is consistent for general alternatives and obtains its limiting distributions under a sequence of local alternatives. Then a Monte Carlo simulation is conducted to study the finite sample level and power behavior of these tests at some alternatives. We also compare the test to an existing lag matched test theoretically and by Monte Carlo experiments.     

Model Averaging for Prediction With Fragmentary Data

ABSTRACT

One main challenge for statistical prediction with data from multiple sources is that not all the associated covariate data are available for many sampled subjects. Consequently, we need new statistical methodology to handle this type of “fragmentary data” that has become more and more popular in recent years. In this article, we propose a novel method based on the frequentist model averaging that fits some candidate models using all available covariate data. The weights in model averaging are selected by delete-one cross-validation based on the data from complete cases. The optimality of the selected weights is rigorously proved under some conditions. The finite sample performance of the proposed method is confirmed by simulation studies. An example for personal income prediction based on real data from a leading e-community of wealth management in China is also presented for illustration.     

民族平等团结思想与全面建设小康社会

本文从历史发展的角度分别论述了中国共产党三代领导集体对马克思主义民族平等团结思想的继承和发展,指出十六大提出的全面建设小康社会的奋斗目标是在马克思主义与时俱进、理论创新的精神实质下对民族平等团结思想的进一步丰富和发展,认为在新世纪新阶段继续坚持民族平等、维护民族团结,巩固社会主义新型民族关系,对实现全面建设小康社会的宏伟目标均有着重要的理论意义和现实意义。