A Quantitative Risk Assessment of Waterborne Cryptosporidiosis in France Using Second-Order Monte Carlo Simulation

A pragmatic quantitative risk assessment (QRA) of the risks of waterborne Cryptosporidium parvum infection and cryptosporidiosis in immunocompetent and immunodeficient French populations is proposed. The model takes into account French specificities such as the French technique for oocyst enumeration performance and tap water consumption. The proportion of infective oocysts is based on literature review and expert knowledge. The probability of infection for a given number of ingested viable oocysts is modeled using the exponential dose-response model applied on published data from experimental infections in immunocompetent human volunteers challenged with the IOWA strain. Second-order Monte Carlo simulations are used to characterize the uncertainty and variability of the risk estimates. Daily risk of infection and illness for the immunocompetent and the immunodeficient populations are estimated according to the number of oocysts observed in a single storage reservoir water sample. As an example, the mean daily risk of infection in the immunocompetent population is estimated to be 1.08 x 10(-4) (95% confidence interval: [0.20 x 10(-4); 6.83 x 10(-4)]) when five oocysts are observed in a 100 L storage reservoir water sample. Annual risks of infection and disease are estimated from a set of oocyst enumeration results from distributed water samples, assuming a negative binomial distribution of day-to-day contamination variation. The model and various assumptions used in the model are fully explained and discussed. While caveats of this model are well recognized, this pragmatic QRA could represent a useful tool for the French Food Safety Agency (AFSSA) to define recommendations in case of water resource contamination by C. parvum whose infectivity is comparable to the IOWA strain.     

Regulating Shareholder Value: A Case Study of the Introduction of Value–based Measures in a Water Company

The implementation of a value–based measurement system within a privatized UK regional water company is examined by means of a longitudinal case study. Evidence is presented of how the system was developed within the context of a regulatory environment, which presented special considerations to the company in designing and implementing an appropriate system. In particular the paper considers the implementation issues surrounding the management of the introduction of the value–based measures at the operational level. The authors describe the drivers behind the introduction of the new system and the technical, political and cultural challenges raised by its implementation.     

The Quality of Skill Acquisition in Young Workers' First Job

Young workers' experiences of their first job form an important stage in the transition from school to work, and the quality of that experience is likely to have a strong bearing on future chances in the labour market. We provide evidence on a key aspect of that experience, namely, whether the skills acquired during the first job are firm-specific or in some degree transferable. More than one in six young people acquired only firm-specific skills in their first substantial job. High levels of prior human capital, short training spells or training leading to qualifications tend to raise, while being in casual or temporary jobs tends to lower, the likelihood that transferable skills are acquired.     

Advancing Gendered Analyses of Entrepreneurship: A Critical Exploration of Entrepreneurial Activity among Gay Men and Lesbian Women

This paper advances contemporary gendered analyses of entrepreneurial activity by exploring self‐employment amongst gay men and lesbian women. Within current entrepreneurial debate, heterosexual women have become the visible embodiment of the gendered subject. Our contribution is to queer this assumption when focusing upon the entrepreneurial activity of gays and lesbians. Our core question investigates if ‘there is evidence of differences between homosexuals and heterosexuals in their likelihood of being entrepreneurially active’. To address this question, we contrast competing notions of gender stereotypes and discrimination whilst drawing on findings from a large‐scale population‐based study of 163,000 UK adults. We find few differences between homosexuals and heterosexuals; this persists after examining intersectional patterns and considering if gay and lesbian entrepreneurs choose particular sectors, geographies or forms of self‐employment. As our discussion highlights, the value of this study lies within its critique of contemporary analyses of gender which assume it is an end‐point rather than a foundation for analysing gender as a multiplicity.     

Nonresponse in repeat population-based voluntary counseling and testing for HIV in rural Malawi

Despite the increasing number of population-based surveys in sub-Saharan Africa that provide testing and counseling for HIV over the past decade, understanding the nature of nonresponse in these surveys, especially panel HIV surveys, is still limited. This article uses longitudinal HIV data collected from rural Malawi in 2004 and 2006 to examine nonresponse in repeat population-based testing. It shows that nonresponse in repeat testing led to significant bias in the estimates of HIV prevalence and to inconsistent conclusions about the predictors of HIV status. In contrast, previous cross-sectional analyses found that nonresponse does not significantly bias the estimates of HIV prevalence. The difference in conclusions from cross-sectional and longitudinal analyses of nonresponse can be attributed to two factors: the different definitions of what constitutes nonresponse in both contexts, and the risk profiles of the missed populations. In particular, although refusal and temporary absence are the major sources ofnonresponse in the cross-sectional contexts, attrition attributable to mortality and out-migration are additional sources of nonresponse in repeat testing. Evidence shows that out-migrants have higher HIV prevalence than nonmigrants, which could account for significant bias in the estimates of prevalence among participants in both tests observed in this study.     

The municipal solid waste and the quality of life of collectors of recyclable materials in Juiz de Fora, Minas Gerais

The generation growing and diversified of Municipal Solid Waste is configured as an environmental problem, economic and social deterioration, especially, by application of inappropriate management of them. Faced with this urban context, the research in development presents as specific objective assessment of the quality of life of the gatherers of recyclable materials were active in the city of Juiz de Fora, in the brazilian state of Minas Gerais. In addition, the objective is, still, the recognition of the activity of sorting performed by "scavengers" in order to maximize the reduction, reuse and recycling energy and material waste daily. The proposed methodology is based on the application of the questionnaire Word Health Organization Quality of Life (WHOQOL-100), prepared by the World Health Organization, in order to value the quality of life of the gatherers of recyclable materials, involved, even in educational workshops in order to discuss and organize strategies of health care and scouting to the basement to public policies.     

The role of The Boffin as abject Other in gendered performances of school achievement

The gendered subjectivities of high achieving school pupils are examined, demonstrating the uneasy relationship between high educational achievement and peer popularity. Drawing on data from a study involving classroom observation and interviews with 71 high-achieving pupils across nine secondary schools in England, the article focuses on the gendered construction of The Boffin. Judith Butler's work, and Hannah Arendt's conception of pariahs and parvenus, are applied to analyse The Boffin as pariah, and as 'queer' in the classroom. The article explores the ways in which this construction is gendered, and the consequences of its application for girls and boys. It is argued that application of this stigmatised term functioned as a powerful deterrent to 'excessive' performances of achievement, for all pupils. But the risks are particularly acute for boys, to whom the 'naming' of Boffin appeared more readily applied, and for whom marginalization as Boffin appears especially perilous (risking particularly pernicious forms of punishment at the hands of other boys).     

Men's psychological functioning in the context of women's breast cancer

Previous research indicates that men are affected when their female partners have breast cancer. However, little is known about what predicts men's psychological well-being in this context. The current investigation involved couples in which the woman had early stage breast cancer and explored the degree to which men's positive and negative well-being was related to women's well-being, women's physical symptoms, relationship functioning, and relationship duration. The findings indicate that all of these factors play a role and interact in predicting men's well-being. In particular, when women have a high level of physical symptoms, the typical associations between men's well-being with women's well-being and relationship adjustment no longer persist. Implications for working with couples addressing health problems are provided.     

The struggle for hegemony: the emergence of a counter-public sphere in post-1997 Hong Kong

The present study examines the struggle for hegemony in the public sphere by two different systems, following Hong Kong’s handover to China in 1997. It has been postulated that the new media, particularly social media, has become an important public sphere for the citizens of Hong Kong to engage in an anti-hegemonic struggle against China’s discursive encroachment into Hong Kong since 1997. Given that the public platform provided by legacy media has been bought out or coopted by China, new media has begun to serve as a subaltern public sphere to enable resisting the hegemony imposed by China. This was analyzed through a survey conducted as part of this study, which showed that people who are young, read the Apple Daily, have high expectations of local autonomy, and a high regard for press freedom are prone to using social media to obtain their social and political information. This article analyzes the implications of the emergence of a counter-China hegemonic public sphere.