Do infants express discrete emotions? Adult judgments of facial,vocal, and body actions

Adult judges were presented with videotape segments showing an infant displaying facial configurations hypothesized to express discomfort/pain, anger, or sadness according to differential emotions theory (Izard, Dougherty, & Hembree, 1983). The segments also included the infant's nonfacial behavior and aspects of the situational context. Judges rated the segments using a set of emotion terms or a set of activity terms. Results showed that judges perceived the discomfort/pain and anger segments as involving one or more negative emotions not predicted by differential emotions theory. The sadness segments were perceived as involving relatively little emotion overall. Body activity accompanying the discomfort/pain and anger configurations was judged to be more jerky and active than body activity accompanying the sadness configurations. The sadness segments were accompanied by relatively little body movement overall. The results thus fail to conform to the predictions of differential emotions theory but provide information that may contribute to the development of a theory of infant expressive behavior.This article is based on the second author's master's thesis. The authors thank Dennis Ross for his expert assistance in the data analyses.     

Living with Dementia: Lay Definitions of Alzheimer's Disease among African American Caregivers and Sufferers

While the medical world aggressively pursues scientific knowledge about Alzheimer's disease, sufferers and caregivers live with this ailment, not as patients, but as people going about their lives, needing and providing care. This article reports explanations of Alzheimer's from the perspectives of African American family caregivers and sufferers. Data were collected from thirty‐six families using participant observation and focus group interviews. Although caregivers sought and used medical expertise, their explanations of Alzheimer's were not only nonmedical, but not necessarily explanations of illness per se. Alzheimer's was presented instead as a way of being, predominantly characterized by views of the sufferer as childlike and by issues of continuity/discontinuity, though some saw Alzheimer's as part of a larger picture.     

Small-Sample Comparisons for Goodness-of-Fit Statistics in One-Way Multinomials with Composite Hypotheses

The small-sample behaviour of power-divergence goodness-of-fit statistics with composite hypotheses was evaluated with multinomial models of up to five cells and up to three parameters. Their performance was assessed by comparing asymptotic test sizes with exact test sizes obtained by enumeration in the near right tail, where 1-?∈?(0.90,?0.95], and in the far right tail, where 1-?∈?(0.95,?0.99]. The study addressed all combinations of power-diparse JAS312HH01.sgmvergence estimates of indices ν?∈?{-1/2,?0,?1/3,?1/2,?2/3,?1,?3/ 2} and power-divergence statistics of indices λ?∈?{-1/2,?0,?1/3,?1/2,?2/3,?1,?3/2}. The results indicate that the asymptotic approximation is sufficiently accurate (by the criterion that the average exact size is no larger than ±10% of the nominal asymptotic test size) in the near right tail when ν=0 and λ=1/2, and in the far right tail when ν=0 and λ=1/3, in both cases providing that the smallest expectation in the composite hypothesis exceeds 5. The only exception to this rule is the case of models that render a near-equiprobable composite hypothesis on the boundaries of the parameter space, where average exact sizes are usually quite different from nominal sizes despite the fact that the smallest expectation in these conditions is usually well above 5.     

The Impact of Cytochrome P450 2E1-Dependent Metabolic Variance on a Risk-Relevant Pharmacokinetic Outcome in Humans

Risk assessments include assumptions about sensitive subpopulations, such as the fraction of the general population that is sensitive and the extent that biochemical or physiological attributes influence sensitivity. Uncertainty factors (UF) account for both pharmacokinetic (PK) and pharmacodynamic (PD) components, allowing the inclusion of risk-relevant information to replace default assumptions about PK and PD variance (uncertainty). Large numbers of human organ donor samples and recent advances in methods to extrapolate in vitro enzyme expression and activity data to the intact human enable the investigation of the impact of PK variability on human susceptibility. The hepatotoxicity of trichloroethylene (TCE) is mediated by acid metabolites formed by cytochrome P450 2E1 (CYP2E1) oxidation, and differences in the CYP2E1 expression are hypothesized to affect susceptibility to TCE's liver injury. This study was designed specifically to examine the contribution of statistically quantified variance in enzyme content and activity on the risk of hepatotoxic injury among adult humans. We combined data sets describing (1) the microsomal protein content of human liver, (2) the CYP2E1 content of human liver microsomal protein, and (3) the in vitro Vmax for TCE oxidation by humans. The 5th and 95th percentiles of the resulting distribution (TCE oxidized per minute per gram liver) differed by approximately sixfold. These values were converted to mg TCE oxidized/h/kg body mass and incorporated in a human PBPK model. Simulations of 8-hour inhalation exposure to 50 ppm and oral exposure to 5 micro g TCE/L in 2 L drinking water showed that the amount of TCE oxidized in the liver differs by 2% or less under extreme values of CYP2E1 expression and activity (here, selected as the 5th and 95th percentiles of the resulting distribution). This indicates that differences in enzyme expression and TCE oxidation among the central 90% of the adult human population account for approximately 2% of the difference in production of the risk-relevant PK outcome for TCE-mediated liver injury. Integration of in vitro metabolism information into physiological models may reduce the uncertainties associated with risk contributions of differences in enzyme expression and the UF that represent PK variability.     

An overview of current clinical issues in separation and placement

This article reviews a wide range of literature and the knowledge base that is necessary for effective treatment of children in foster and adoptive homes. The pitfalls in clinical work with placed children are identified. In addition to the psychological effects of placement on children, there is review of knowledge affecting both foster and adoptive parents. Treatment approaches and tools that are presented in the literature are summarized.     

Therapeutic interventions with families with psychotic young children

Mahler's theory of infantile psychosis focuses on the distortion or omission of the symbiotic relationship between mother and child. The child's defective utilization of the mother, often a result of constitutional vulnerability, prevents internalization of the mother's functions, ego development, and differentiation of self. The child's deficiency may also exacerbate the mother's vulnerabilities, causing her to respond in ways which further inhibit the child's development. This article presents the treatment of two families, each with a child suffering from infantile psychosis.     

Infant “surprise” expressions as coordinative motor structures

This study found that the facial action of moderately or widely opening the mouth is accompanied by brow raising in infnats, thus producing surprise expressions in non-surprise situations. Infants (age = 5 months and 7 months) were videotaped as they were presented with toys that they often grasped and brought to their mouths. Episodes of mouth opening were identified and accompanying brow, nose, and eyelid movements were coded. Results indicated that mouth opening is selectively associated with raised brows rather than to other brow movements. Trace levels of eyelid raising also tended to accompany this facial configuration. The findings are discussed in terms of a dynamical systems theory of facial behavior and suggest that facial expression cannot be used as investigators' sole measure of surprise in infants.This research was conducted as part of the second author's undergraduate honors program project and was supported in part by a grant from the NICHHD #1RO1 HD 22399-A3 awarded to G. F. Michel.     

Mothers construct fathers: Destabilized patriarchy in La Leche League

This paper examines changing masculine ideals from the point of view of women homemakers through a case study of La Leche League, a maternalist organization dedicated to breastfeeding and mother primacy. We suggest two reasons for studying the League: first, an emerging literature suggests that changing norms are seeping into many such seemingly conservative groups, and second, the League continues to be highly successful among white, middle-class, married women. The paper looks at two aspects of masculinity, examining changes in the League through fieldwork, interviews, and content analysis, and finds that new norms of increased father involvement and decreased rights over women's bodies have both influenced League philosophy. We conclude that while in some respects a measure of the decline of men's patriarchal privileges, the League's changes also may contribute to a restabilization of male dominance in a modified, partial form.