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Loss of well-being, rising rates of depression and various psychological illnesses are a public health concern. This study aims to explore the associations between cultural access and mental illness. Applying a panel methodology to the 20 Italian regions (2002–2007 period) the relationship between public health expenditure per-capita (the dependent variable) and hospital discharge rates for different illnesses (the regressors) has been estimated. Then the impact of the private spending in culture (the regressors) on the mental illness—as approximated by the discharge rate for mental illness—(the dependent variable), has been verified via generalised method of moments (GMM) approach. Data came from the National Census of the Italian Institute of Statistics (ISTAT). The results of empirical analysis have highlighted how the discharge rate for mental illness is substantially improved by some forms of cultural consumptions. The coefficients associated with unemployment rates (the control variables) have a positive impact on mental illness, thus suggesting that unemployment has an impact on the discharge rate for mental illness; the greatest impact is observed for the long-term unemployment rate. The results are beneficial for designing and implementing preventive strategies to reduce mental illness and public health expenditure by considering the impact of cultural access.  相似文献   
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Reversible jump Markov chain Monte Carlo (RJMCMC) algorithms can be efficiently applied in Bayesian inference for hidden Markov models (HMMs), when the number of latent regimes is unknown. As for finite mixture models, when priors are invariant to the relabelling of the regimes, HMMs are unidentifiable in data fitting, because multiple ways to label the regimes can alternate during the MCMC iterations; this is the so-called label switching problem. HMMs with an unknown number of regimes are considered here and the goal of this paper is the comparison, both applied and theoretical, of five methods used for tackling label switching within a RJMCMC algorithm; they are: post-processing, partial reordering, permutation sampling, sampling from a Markov prior and rejection sampling. The five strategies we compare have been proposed mostly in the literature of finite mixture models and only two of them, i.e. rejection sampling and partial reordering, have been presented in RJMCMC algorithms for HMMs. We consider RJMCMC algorithms in which the parameters are updated by Gibbs sampling and the dimension of the model changes in split-and-merge and birth-and-death moves. Finally, an example illustrates and compares the five different methodologies.  相似文献   
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Single-case experiments are frequently used to do research involving a clinical intervention, since large-n trials are often impractical in clinical research. In order to investigate a possible difference in the effect of the treatments considered in the study, nonparametric instruments are valid tools; in particular, permutation solutions work well when we wish to assess differences in treatment effects. We present an extension of a permutation solution to the multivariate response case and to the case of replicated single-case experiments. A simulation study shows that the approach is both reliable under the null hypothesis and powerful under the alternative. At the end, we present the results of an application to two real experiments.  相似文献   
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Research involving a clinical intervention is normally aimed at testing the treatment effects on a dependent variable, which is assumed to be a relevant indicator of health or quality-of-life status. In much clinical research large-n trials are in fact impractical because the availability of individuals within well-defined categories is limited in this application field. This makes it more and more important to concentrate on single-case experiments. The goal with these is to investigate the presence of a difference in the effect of the treatments considered in the study. In this setting, valid inference generally cannot be made using the parametric statistical procedures that are typically used for the analysis of clinical trials and other large-n designs. Hence, nonparametric tools can be a valid alternative to analyze this kind of data. We propose a permutation solution to assess treatment effects in single-case experiments within alternation designs. An extension to the case of more than two treatments is also presented. A simulation study shows that the approach is both reliable under the null hypothesis and powerful under the alternative, and that it improves the performance of a considered competitor. In the end, we present the results of a real case application.  相似文献   
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The principal aim of this paper is to present an evolutionary model based on a simple inequality system which shows how altruism can increase exchanges of goods and services, in order to study the conditions which can permit the emergence and prevalence of altruistic behaviors. We will show that given certain conditions, and even without considering group selection, kin selection or reciprocal altruism, altruists may have a greater probability of survival than egoists.  相似文献   
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The purpose of this article is to discuss the application of nonlinear models to price decisions in the framework of rating-based product preference models. As revealed by a comparative simulation study, when a nonlinear model is the true model, the traditional linear model fails to properly describe the true pattern. It appears to be unsatisfactory in comparison with nonlinear models, such as logistic and natural spline, which offer some advantages, the most important being the ability to take into account more than just linear and/or monotonic effects. Consequently, when we model the product preference with a nonlinear model, we are potentially able to detect its ‘best’ price level, i.e., the price at which consumer preference towards a given attribute is at its maximum. From an application point of view, this approach is very flexible in price decisions and may produce original managerial suggestions which might not be revealed by traditional methods.  相似文献   
70.
Multivariate combination-based permutation tests have been widely used in many complex problems. In this paper we focus on the equipower property, derived directly from the finite-sample consistency property, and we analyze the impact of the dependency structure on the combined tests. At first, we consider the finite-sample consistency property which assumes that sample sizes are fixed (and possibly small) and considers on each subject a large number of informative variables. Moreover, since permutation test statistics do not require to be standardized, we need not assume that data are homoscedastic in the alternative. The equipower property is then derived from these two notions: consider the unconditional permutation power of a test statistic T for fixed sample sizes, with V ? 2 independent and identically distributed variables and fixed effect δ, calculated in two ways: (i) by considering two V-dimensional samples sized m1 and m2, respectively; (ii) by considering two unidimensional samples sized n1 = Vm1 and n2 = Vm2, respectively. Since the unconditional power essentially depends on the non centrality induced by T, and two ways are provided with exactly the same likelihood and the same non centrality, we show that they are provided with the same power function, at least approximately. As regards both investigating the equipower property and the power behavior in presence of correlation we performed an extensive simulation study.  相似文献   
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