俄罗斯证券市场:发展特点与发展战略

随着俄罗斯金融体制改革的深入,俄证券市场得到了较为迅速的发展。特别是20世纪90年代中期以来,加速发展的世界有价证券市场的全球化进程,对俄罗斯产生了较大的影响。俄罗斯为迎接经济全球化挑战并融入该进程,正在着手制定全面而综合的证券市场发展战略。本文对俄罗斯证券市场的发展特点与发展战略进行了分析和评价。     

Unifying CRM and EWOC designs for phase I cancer clinical trials

The main goal of phase I cancer clinical trials is to determine the highest dose of a new therapy associated with an acceptable level of toxicity for the use in a subsequent phase II trial. The continual reassessment method (CRM) [O’Quigley, J., Pepe, M., Fisher, L., 1990. Continual reassessment method: a practical design for phase I clinical trials in cancer. Biometrics 46, 33–48] and escalation with overdose control (EWOC) [Babb, J., Rogatko, A., Zacks, S., 1998. Cancer phase I clinical trials: efficient dose escalation with overdose control. Statist. Med. 17 (10), 1103–1120] are two model-based designs used for phase I cancer clinical trials. A few modifications of the (original) CRM and EWOC have been made by many authors. In this paper, we show how CRM and EWOC can be unified and present a hybrid design. We study the characteristics of the approach of the hybrid design. The comparisons of the three designs (CRM, EWOC, and the hybrid design) are presented by convergence rates and overdose proportions. The simulation results show that the hybrid design generally has faster convergence rates than EWOC and smaller overdose proportions than CRM, especially when the true maximum tolerated dose (MTD) is above the mid-level of the dose range considered. The performance of these three designs is also evaluated in terms of sensitivity to outliers.     

A clarifying comparison of methods for controlling the false discovery rate

Traditional multiple hypothesis testing procedures fix an error rate and determine the corresponding rejection region. In 2002 Storey proposed a fixed rejection region procedure and showed numerically that it can gain more power than the fixed error rate procedure of Benjamini and Hochberg while controlling the same false discovery rate (FDR). In this paper it is proved that when the number of alternatives is small compared to the total number of hypotheses, Storey's method can be less powerful than that of Benjamini and Hochberg. Moreover, the two procedures are compared by setting them to produce the same FDR. The difference in power between Storey's procedure and that of Benjamini and Hochberg is near zero when the distance between the null and alternative distributions is large, but Benjamini and Hochberg's procedure becomes more powerful as the distance decreases. It is shown that modifying the Benjamini and Hochberg procedure to incorporate an estimate of the proportion of true null hypotheses as proposed by Black gives a procedure with superior power.     

Random translation of discrete order statistics

We investigate the existence and uniqueness of a discrete parent distribution supported on the integers whose order statistics are related by a random translation. We also provide some examples using the constructive method that we propose.     

对股权的霍菲尔德式分析——一种分析法学的思路

揭示目前我国学者有关股权学说的一些不足之处,以霍菲尔德的分析法学概念对股权问题作了初步分析。试图为公司法学的研究引入一种新的思路和方法。     

唐宋国有土地政策的变化及其量化分析

唐宋时期,国有土地政策与以往相比发生了显著变化——将国有逐渐转为私有,其中第一步即是改变经营方式。通过对经营方式变化前后国家收益的量化分析,指出经营制度的变化促进了国有资产的经济增长,从而为唐宋经济增长增加了原动力。     

解读王尔德唯美童话背后的呼唤

奥斯卡·王尔德是英国著名的唯美主义作家代表。他的童话用隐藏在童话外衣下的残酷折射了世间的冷酷和不公。在童话中,他始终贯彻唯关主义理念,对人物景致的刻画美轮美奂,而这唯美的刻画却总是逃脱不了死亡和悲惨的结局。完美的情节和悲惨的结局形成了强烈的反差,在这种反差之下读者的心被撕成了碎片;在美与丑的强烈对比中,读者与王尔德的呐喊产生了共鸣,听到了王尔德对于真善美无声的呼唤。     

对做好高校贫困学生工作的思考

当前高校贫困生问题日益凸显,在一定程度上影响了贫困生的生活、学习、心理健康和长远发展。切实解决高校贫困生问题,首先必须充分认识解决贫困生问题的重要意义;同时,以政府统筹,政策导向为根本,积极构建助困与扶志相结合的多渠道资助机制,动员全社会广泛参与,共同解决高校贫困生问题。     

论高校办公室管理的现代化建设

高校办公室要努力实现管理观念、管理制度、管理人才和管理手段的现代化,切实发挥其“中枢”、“窗口”和“桥梁”作用并积极促进学校的现代化建设