Ten steps to developing a national agenda to address financial conflicts of interest in industry sponsored clinical research

Financial liaisons between clinical researchers, research institutions, and industrial sponsors have gained momentum in recent years. In the process, it has been argued by many that trust in the research infrastructure is being eroded by the financial conflicts of interest that emerge from these arrangements. Yet, the financial resources of industry are needed to continue technology transfer from the bench to the bedside. Policy makers and government regulators are currently struggling to determine how to best manage financial conflicts of interest that emerge from these liaisons. Various organizations and government entities have proposed different strategies. This paper explores the limitations of existing measures and recommends that a unified national agenda is needed. We propose 10 steps to develop an agenda to address financial conflicts of interest in industry-sponsored clinical research.     

WORK INCENTIVES AND SOLE MOTHERS: COMPARING AUSTRALIAN POLICY

This article adopts a comparative perspective on policies to increase labour force participation of single mothers. Australia's orientation is briefly explored within the context of other major English-speaking countries (the United States, Britain and Canada), and the common emphasis in the policies on providing employment services and reducing poverty traps for Australia and Canada's largest province (Ontario) is then examined. While the potential of these approaches to increase labour force participation is found to be limited, the comparison suggests that Canada would do well to follow some of the recent anti-poverty measures Australia has adopted. Australia, however, appears to offer a less favourable employment climate for women. The article concludes that both jurisdictions will need to pursue a broader set of policies to respond to the root causes of poverty among women heading families on their own.     

Who Gets Custody Now? Dramatic Changes in Children’s Living Arrangements After Divorce

This article reexamines the living arrangements of children following their parents’ divorce, using Wisconsin Court Records, updating an analysis that showed relatively small but significant increases in shared custody in the late 1980s and early 1990s. These changes have accelerated markedly in the intervening years: between 1988 and 2008, the proportion of mothers granted sole physical custody fell substantially, the proportion of parents sharing custody increased dramatically, and father–sole custody remained relatively stable. We explore changes in the correlates of alternative custody outcomes, showing that some results from the earlier analysis still hold (for example, cases with higher total family income are more likely to have shared custody), but other differences have lessened (shared-custody cases have become less distinctive as they have become more common). Despite the considerable changes in marriage and divorce patterns over this period, we do not find strong evidence that the changes in custody are related to changes in the characteristics of families experiencing a divorce; rather, changes in custody may be the result of changes in social norms and the process by which custody is determined.     

Evaluating the causal economic impacts of transport investments: evidence from the Madrid–Barcelona high speed rail corridor

This paper evaluates economic impacts arising from the introduction of high-speed rail (HSR) between Madrid and Barcelona. Using difference-in-differences estimation we estimate an average treatment effect for provinces with stops on the HSR line of 2.4% for economic output, 3.3% for numbers of firms, and 1.1% for labour productivity. We complement our DID results with a synthetic control analysis for Lleida and Tarragona, two provinces that we argue were assigned HSR stations largely due to their incidental location. We find that both the number of firms and labour productivity are substantially higher in these provinces than in their synthetic counterparts.     

How do my parents react when I feel happy? Longitudinal associations with adolescent depressive symptoms,anhedonia, and positive affect regulation

Parental emotion socialization plays a role in the development of adolescents’ emotion regulation and is associated with adolescents’ depressive symptoms. Most research has focused on parental socialization of negative affect. The scarce research on parental socialization of positive affect (PA) shows that parental downgrading responses to adolescents’ PA are associated with concurrent adolescent depression. The aims of the present study were to examine longitudinal associations of both maternal and paternal responses to adolescents’ PA with how adolescents regulate their PA (i.e., dampening and enhancing) and with adolescents’ general depressive symptoms and anhedonia. We also considered associations in the opposite direction from adolescent regulatory responses and symptoms to parental responses. In a two‐wave study (1‐year interval), 635 adolescents from Grade seven completed questionnaires. Cross‐sectionally, maternal and paternal responses to adolescents’ PA were associated with concurrent adolescents’ PA regulation as well as adolescents’ depressive and anhedonic symptoms. Longitudinally, low maternal and paternal enhancing responses to adolescents’ PA predicted relative increases in anhedonic symptoms and relative decreases in adolescent enhancing over time. Low maternal enhancing was also predictive of relative increases in depressive symptoms. The present study points to bidirectionality of relations as adolescents’ level of depressive symptoms predicted maternal and paternal responses.     

Strengthening kinship families: scoping the provision of respite care in Australia

Kinship care is the fastest growing form of out‐of‐home care in Australia, as it is in many other countries. The Victorian Government's response has been to establish 18 programmes across the state to provide support to kinship families. The scoping project described here, based on interviews with key programme staff, explores the experiences of the new programmes in providing support, specifically respite care, to kinship families. It has produced a picture, based on qualitative and quantitative data, of how respite care is understood, the perceived respite needs of kinship families, how services are organized and provided, identified barriers to families accessing support, the effect of respite provision and what constitutes optimal practice. The findings establish a basis for a best practice model of service provision for this increasingly significant family type.