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21.
This article, which has its origin in a feasibility study carried out for three youth telephone helplines, focuses on gender, difference and helpline access by young people. During the research process the writers noted that for the three commissioning helplines, as is the case with the majority of other telephone helplines, approximately two‐thirds of callers are female. A helpline for young Muslims where the gender access ratio was 50/50 stood out as being different in this respect. Until recently, literature on gender and help‐seeking has tended towards making a blanket identification of males as experiencing difficulties in negotiating pathways to help. Although this difficulty of males is evident in relation to both help‐seeking and access to helplines, our study suggests that, at least in relation to helpline usage, when we take culture, ethnicity and sexuality into account, the help‐seeking situation may be more nuanced. This has implications in terms of enabling a cross‐section of young people to access helplines as well as with regard to helpline service development. 相似文献
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The completely random character of radioactive disintegration provides the basis of a strong justification for a Poisson linear model for single-photon emission computed tomography data, which can be used to produce reconstructions of isotope densities, whether by maximum likelihood or Bayesian methods. However, such a model requires the construction of a matrix of weights, which represent the mean rates of arrival at each detector of photons originating from each point within the body space. Two methods of constructing these weights are discussed, and reconstructions resulting from phantom and real data are presented. 相似文献
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Peter J. Robinson 《Risk analysis》1992,12(1):139-148
Because of the inherent complexity of biological systems, there is often a choice between a number of apparently equally applicable physiologically based models to describe uptake and metabolism processes in toxicology or risk assessment. These models may fit the particular data sets of interest equally well, but may give quite different parameter estimates or predictions under different (extrapolated) conditions. Such competing models can be discriminated by a number of methods, including potential refutation by means of strategic experiments, and their ability to suitably incorporate all relevant physiological processes. For illustration, three currently used models for steady-state hepatic elimination--the venous equilibration model, the parallel tube model, and the distributed sinusoidal perfusion model--are reviewed and compared with particular reference to their application in the area of risk assessment. The ability of each of the models to describe and incorporate such physiological processes as protein binding, precursor-metabolite relations and hepatic zones of elimination, capillary recruitment, capillary heterogeneity, and intrahepatic shunting is discussed. Differences between the models in hepatic parameter estimation, extrapolation to different conditions, and interspecies scaling are discussed, and criteria for choosing one model over the others are presented. In this case, the distributed model provides the most general framework for describing physiological processes taking place in the liver, and has so far not been experimentally refuted, as have the other two models. These simpler models may, however, provide useful bounds on parameter estimates and on extrapolations and risk assessments. 相似文献
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Allan F. Abrahamse Peter A. Morrison Nancy Minter Bolton 《Population research and policy review》1994,13(4):383-398
Surname analysis is a potentially useful technique for identifying members of particular racial, ethnic, or language communities within a population. We review the existing state of the art for identifying persons of Hispanic or Asian origin, based on surnames distinctive of each group. We describe the logic of surname analysis, profile several available surname dictionaries, and illustrate their applications in local redistricting. Results of our ongoing validation studies suggest promising future directions for improving accuracy and broadening applications.This article is based on a paper presented at the annual Population Association of America meetings at Cincinnati, 1 April 1993. 相似文献
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Using the 1990 Census of Population, Thieblot (1999) argued that black employment and the strength of the prevailing wage
laws are correlated and that repeal of these laws would lead to higher black employment in construction. Analysis of the 1970
Census of Population reveals that the relative abundance of black construction workers in the group of states that eventually
would repeal their laws preceded those repeals and that this is mainly due to the characteristics of Southern labor markets.
This and other research cast doubt on both the strength and the existence of such a correlation. 相似文献