保山盆地羊邑组二～三段高分辨率层序地层分析

通过精细划分对比地层、深入分析层序结构、建立层序地层格架,综合分析了保山盆地的露头剖面、钻井岩芯、测井资料,在羊邑组二～三段内识别出了3类不同级次的层序界面。根据划分出的各层序界面将羊邑组二～三段细分为9个中期、31个短期、66个超短期基准面旋回层序。在此基础上,分析了各级次基准面旋回层序的垂向序列、岩性岩相组合、结构类型及叠加样式等特征,重点讨论了向上“变深”的非对称型和对称型2类超短期基准面旋回层序类型。进一步探讨了高分辨率层序地层学在扇三角洲-湖泊沉积体系的地层划分与对比、地层格架构建中的应用。     

全过程培养学生职业能力的实践与探索——以河北旅游职业学院导游专业为例

从导游专业人才培养模式构建、课程体系重构、实境教学和学生课外活动等方面,对该专业学生职业能力培养过程进行了探索,提出了全过程培养导游专业学生职业能力的观点,取得了明显成效。     

A Bayesian optimal interval design for dose optimization with a randomization scheme based on pharmacokinetics outcomes in oncology

The primary objective of an oncology dose-finding trial for novel therapies, such as molecularly targeted agents and immune-oncology therapies, is to identify the optimal dose (OD) that is tolerable and therapeutically beneficial for subjects in subsequent clinical trials. Pharmacokinetic (PK) information is considered an appropriate indicator for evaluating the level of drug intervention in humans from a pharmacological perspective. Several novel anticancer agents have been shown to have significant exposure-efficacy relationships, and some PK information has been considered an important predictor of efficacy. This paper proposes a Bayesian optimal interval design for dose optimization with a randomization scheme based on PK outcomes in oncology. A simulation study shows that the proposed design has advantages compared to the other designs in the percentage of correct OD selection and the average number of patients allocated to OD in various realistic settings.     

The Nonprofit Sector and State Governments: Public Policy Issues Facing Nonprofits in North Carolina and Other States

The challenges facing nonprofits in North Carolina and most states include devolution and ripple effects at the state level from federal budget cutbacks, government efforts to tax or further regulate nonprofits, scandals involving a few organizations or their leaders, and efforts to limit nonprofits' right to lobby and advocate for their causes. But the future also holds a number of opportunities for nonprofits, including the increased clout of nonprofits acting together as a sector; partnership initiatives with nonprofits by North Carolina's governor and chief executives in other states, legislative measures to increase charitable giving and reduce red tape, state-level summits following up on the president's push for increased volunteerism, and a reservoir of public trust in nonprofits. North Carolina's experience may predict the future dangers and opportunities in other states.     

我国食品安全危机成因与对策的法学思考

食品安全是一个关乎民生的大问题,但也不是一蹴而就的问题,它同国家经济能力、技术水平和资金支持以及监管制度都密不可分。本文着重从法律的角度对食品安全危机产生的原因及相关的立法对策做出探讨。     

我国资本市场的战略性研究

任何资本市场都有一个潜在的信用危机问题 ,我国资本市场也不例外 ,因此要注意规避我国资本市场潜在的信用风险。加入WTO以后 ,我国资本市场将面临更大的冲击 ,为此必须及早制订相应的对策     

弗朗索瓦丝·萨冈的时间意识及其生存姿态

弗朗索瓦丝.萨冈是以抒写"忧愁"闻名于世的作家,在忧愁的背后是她的时间之伤。其作品中的人物流露出了回避"过去",拒绝思考"将来",存在的只有"现在"的时间意识。在唯一存在的"现时"中,作者有两种时间体验:一类是应消磨掉的空虚时间,另一类是应珍惜的情感时间。基于这两类时间,作者的描写表现出两种倾向:日子的消亡和美好的瞬间。为了尽量延长美好的瞬间以赢取时间,萨冈选择了以幸福为唯一准则的生存姿态。     

中国式民主道路的逻辑形成

中国式民主道路就是中国特色社会主义民主道路,它的形成有着自身特有的逻辑线索,这些逻辑线索深刻地蕴含在中国传统民主思想发展的内在导向中,蕴含在西方民主主义思潮的传播和历史影响中,更蕴含在马克思主义民主理论的指导和根本取向中。中国式民主道路的形成正是中国传统民主思想内在影响、西方民主主义思潮历史影响以及马克思主义民主理论决定性影响三者综合作用、逻辑递进的结果,是在中国共产党领导下顺应历史潮流,并沿着特定的政治发展道路不断推进的。     

论汉英词汇中词义的民族文化特征

汉英词汇在词义内涵上具有复杂的民族文化差异,解释和理解造成其文化差异的原因,是对外汉语词汇教学中需要重视的。对汉英词汇的词义差异产生的原因进行分析,会更清楚地看到民族独特的历史文化是语言的坚实底座,掌握好民族历史文化背景对语言教学大有裨益。