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In the Netherlands, with its remarkably high disability rates, a new phenomenon seems to be emerging. Growing disability rates in the past few years have been exclusively caused by the growing inflow of women into the disability schemes. Comparing the Dutch situation internationally shows that roughly the same problem seems to exist in those countries in which there is a more general problem of large inflow into disability. Women are overrepresented in these arrangements. The Dutch literature shows that there are many factors (both work- and non-work-related) that contribute to a larger push of women towards disability. We conclude that the benefit system can be seen as a sort of "filter". If the filter is weak, many persons will enter disability. If the pressure on women to enter is larger (or the forces to stop women from entering disability smaller), then inflow risks for women will be higher.  相似文献   
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A mechanistic model is presented describing the clearance of a compound in a precision-cut liver slice that is incubated in a culture medium. The problem of estimating metabolic rate constants in PBPK models from liver slice experiments is discussed using identifiability analysis. From the identifiability problem analysis, it appears that in addition to the clearance, the compound's free fraction in the slice and the diffusion rate of the exchange of the compound between culture medium and liver slice should be identified. In addition, knowledge of the culture medium volume, the slice volume, the compound's free fraction, and octanol-water-based partition between medium and slice is presupposed. The formal solution for identification is discussed from the perspective of experimental practice. A formally necessary condition for identification is the sampling of parent compound in liver slice or culture medium. However, due to experimental limitations and errors, sampling the parent compound in the slice together with additional sampling of metabolite pooled from the medium and the slice is required for identification in practice. Moreover, it appears that identification results are unreliable when the value of the intrinsic clearance exceeds the value of the diffusion coefficient, a condition to be verified a posteriori.  相似文献   
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The concept of integration is not well defined. It not known how people with disabilities experience integration. In this study qualitative methods were used. The aim of the article is to define a model of successful integration based on the perspectives of people with disabilities and people within their social environment. Integration consists of five elements: functioning ordinarily without receiving special attention, mixing with others that are not disabled, taking part in society, trying to realize one’s potential and directing one’s own life. Integration is obtained through a process of interaction between a person with a disability and society. This process is influenced by personal, societal and support factors. The individual with a disability and society have a mutual responsibility with respect to integration.  相似文献   
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价值观的形成有其自身的规律 ,并受到社会因素和个体内在因素的影响。当代青年正处在我国改革开放进一步深化和社会主义市场经济体制逐步确立及自我意识发展和自我需要扩大的时期 ,因此 ,他们的价值观必然打着当今时代的烙印 ,具有开放性、先锋化、情绪性等特点 ,他们追求高效、公正、互利 ,追求求职与成才相结合 ,但同时 ,其自身的身心失范问题也日趋严重。  相似文献   
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The concept ‘social control’ has been criticised from a variety of quarters in recent years, particularly by historians and historical sociologists. However, it remains in common usage in sociological studies of welfare, deviance and social control. This paper shows, first, how this reliance on the concept of social control is rooted in a wider-ranging argument in social and political theory concerning the liberal-democratic fusion between the state and civil society, and that the lack of resolution of this argument is the foundation of the persistence of the concept social control in other areas of social inquiry, despite its repeated ‘falsification’. Second, the paper highlights the main arguments against the use of ‘social control’ in explaining social order, in particular the misunderstanding of class, culture and power which its use encourages, and the paper will conclude with a discussion of alternative ways of conceptualising the operation of power in contemporary societies.  相似文献   
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An analysis of 120 corporate websites from Denmark, France, Germany, Norway, Singapore, Spain, the United Kingdom and the United States reveals, for the first time, international results about the implementation and use of virtual press rooms. This article shows the importance that large international companies attribute to Web-based media centers to achieve organizational objectives and to meet journalists’ demands for information and audiovisual resources. The study also shows, however, that most press rooms are far from being complete, efficient, easy-to-use, reliable and updated on a daily basis. In fact, there is not a single country from those analyzed that consistently stands out from the rest. In most of them, good results in certain areas coexist with significant shortcomings in others, resulting in some cases in poor press rooms that may not achieve the desired public relations objectives.  相似文献   
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苏轼一生无论居庙堂之高 ,或处江湖之远 ,皆追求心灵自由 ,达到了物我同一、高凡绝尘的理想境界。该文认为苏轼慕陶、学陶 ,作《和陶诗》12 0余首以明志 ,却始终未能像陶渊明那样挂冠而去 ,归隐田园。究其原因 ,不外乎生活时代、出身背景、思想体系、入仕经历等方面的差异  相似文献   
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