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71.
The problem of finding the optimal timing of audit activities within an organisation has been addressed by many researchers. We propose a stochastic programming formulation with Mixed Integer Linear Programming (MILP) and Constraint Programming (CP) certainty-equivalent models. In experiments neither approach dominates the other. However, the CP approach is orders of magnitude faster for large audit times, and almost as fast as the MILP approach for small audit times. This work generalises a previous approach by relaxing the assumption of instantaneous audits, and by prohibiting concurrent auditing.  相似文献   
72.
This paper examines two potentially contradictory effects of the presence of controlling shareholders. Controlling shareholders have been shown to be beneficial, as they generally have a long-term interest in the firm and are willing and able to monitor the actions of senior managers closely and decrease agency costs between shareholders and management (agency costs of Type I). However, they are also in a position to expropriate the firm’s assets, especially when they are actively involved in management (agency costs of Type II). More specifically, this article reviews how regulatory and legislative bodies have tried to curb the consumption of private benefits by controlling shareholders while preserving the beneficial aspects of their long-term interest and their monitoring role, the effect controlling shareholders on the application and effectiveness of corporate governance best practices as well as on the executive and board member remuneration.  相似文献   
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In this paper we consider the optimal decomposition of Bayesian networks. More concretely, we examine empirically the applicability of genetic algorithms to the problem of the triangulation of moral graphs. This problem constitutes the only difficult step in the evidence propagation algorithm of Lauritzen and Spiegelhalter (1988) and is known to be NP-hard (Wen, 1991). We carry out experiments with distinct crossover and mutation operators and with different population sizes, mutation rates and selection biasses. The results are analysed statistically. They turn out to improve the results obtained with most other known triangulation methods (Kjærulff, 1990) and are comparable to results obtained with simulated annealing (Kjærulff, 1990; Kjærulff, 1992).  相似文献   
75.
The subjective nature of chronic pain leads to challenges in describing, treating, and accommodating pain. Twenty older women, who engaged in focus groups, and eight of whom also participated in individual interviews, discussed the influence of chronic pain on their perception of self as well as daily functioning. Managing pain forced many of the women to withdraw from social activities that they valued and interfered with sleep patterns, household tasks and recreational activities. Varied acceptance by social network members added to the challenge of adjusting to complications associated with pain. Self-care practices that supported independence contributed to women's perceived success in daily functioning.  相似文献   
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This paper analyses two issues related to working conditions and temporary employment. First, why do temporary workers exhibit lower scores in objective indicators of working life? Second, what is the influence of working conditions on mobility? Using information for Spanish workers, the results indicate that differences in working conditions remain after controlling for individual, job and firm characteristics: in particular, temporary workers with short job tenure seem to occupy jobs with poorer working conditions. Moreover, there is evidence that workers with worse working life are more likely to expect to leave their current firms.  相似文献   
78.
The International Council for Harmonization (ICH) E9(R1) addendum recommends choosing an appropriate estimand based on the study objectives in advance of trial design. One defining attribute of an estimand is the intercurrent event, specifically what is considered an intercurrent event and how it should be handled. The primary objective of a clinical study is usually to assess a product's effectiveness and safety based on the planned treatment regimen instead of the actual treatment received. The estimand using the treatment policy strategy, which collects and analyzes data regardless of the occurrence of intercurrent events, is usually utilized. In this article, we explain how missing data can be handled using the treatment policy strategy from the authors' viewpoint in connection with antihyperglycemic product development programs. The article discusses five statistical methods to impute missing data occurring after intercurrent events. All five methods are applied within the framework of the treatment policy strategy. The article compares the five methods via Markov Chain Monte Carlo simulations and showcases how three of these five methods have been applied to estimate the treatment effects published in the labels for three antihyperglycemic agents currently on the market.  相似文献   
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Journal of Management and Governance - Since the beginning of the 2000s, the concept of Business Model has been explored by scholars from a broad range of business studies and particularly those in...  相似文献   
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