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21.
Most models for incomplete data are formulated within the selection model framework. Pattern-mixture models are increasingly seen as a viable alternative, both from an interpretational as well as from a computational point of view (Little 1993, Hogan and Laird 1997, Ekholm and Skinner 1998). Whereas most applications are either for continuous normally distributed data or for simplified categorical settings such as contingency tables, we show how a multivariate odds ratio model (Molenberghs and Lesaffre 1994, 1998) can be used to fit pattern-mixture models to repeated binary outcomes with continuous covariates. Apart from point estimation, useful methods for interval estimation are presented and data from a clinical study are analyzed to illustrate the methods. 相似文献
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23.
In this article, using multiple illustrative case examples, we demonstrate that philanthropic institutions are in the business of creating public value. In framing the work of philanthropy more broadly to include the process of public value creation, philanthropic institutions and leaders are challenged to be more strategic not only in their mission‐fulfillment grant‐making with nonprofit organizations but also in the way they stimulate and encourage collaboration, create the “third space” necessary to incubate ideas to transform society, and leverage resources to increase the return on their investments toward system‐wide change. The implications for philanthropic actors and institutions suggest that the strategic contributions they make toward creation of public value are those that go beyond transactional performance measures, such as number of dollars spent or clients receiving services, to include ways that their investments are amplified by meaningful partnerships with nonprofit and other organizations, changed behaviors of institutions and individuals, and transformative public policies. 相似文献
24.
Public Organization Review - High levels of sub-national policy experimentation and public cynicism about politics and government, combined with significant challenges and opportunities for... 相似文献
25.
The assessment of company performance is one of the major dilemmas facing the strategic researcher. This paper reviews the alternative methods available, then uses one approach, peer assessment, to produce a guide to British company performance. Britain's best companies are identified and their profiles are examined. Their declared financial strengths and relative weaknesses in marketing and innovation are identified. 相似文献
26.
Stuart R Timperley 《Omega》1973,1(5):621-628
It would appear that most discussions on manpower or personnel planning are concerned with highlighting the dichotomy between organizational needs and personal needs. The assumption that these two separate need areas can be successfully harmonized through personnel planning is implicit. In this paper the intention is to discuss this relationship in terms of the consequences for employees of attempts to achieve the aims of organizational manpower plans through the establishment of personnel control mechanisms. 相似文献
27.
Louisa Degenhardt Carolyn Day Elizabeth Conroy Stuart Gilmour 《Journal of sex research》2013,50(2):107-114
We examined potential links between cocaine use and street‐based sex work in New South Wales, Australia, following reports of increased cocaine use among injection drug users (IDU). Police data on prostitution and possession/use of cocaine was analysed using time series analysis. Interviews with key informants and IDU were also conducted, and data on cocaine use from ongoing monitoring systems targeted at IDU were analyzed. There was a clear increase in cocaine use among IDU which occurred in 2001. This occurred at the same time as an increase in prostitution offenses. Qualitative data suggested a greater number of primary heroin users were engaging in street‐based sex work, which was driven in part by the increases in cocaine use among this group. Subsequent reductions in cocaine availability led to decreased cocaine use and possession offenses, along with reductions in prostitution offenses. 相似文献
28.
A. Nayena Blankson Marion O'Brien Esther M. Leerkes Stuart Marcovitch Susan D. Calkins 《Social Development》2012,21(1):1-20
In this study, we examined the hypothesis that preschoolers' performance on emotion and cognitive tasks is organized into discrete processes of control and understanding within the domains of emotion and cognition. Additionally, we examined the relations among component processes using mother report, behavioral observation, and physiological measures of emotion control. Participants were 263 children (42 percent non‐White) and their mothers. Results indicated that the three approaches of measuring emotion control were unrelated. Regardless of the measurement method, a four‐factor solution differentiating emotion control and understanding and cognitive control and understanding fits the data better than did either of two two‐factor models, one based on domains of emotion and cognition across processes, and one based on processes of control and understanding across domains. Results of this research replicate those of Leerkes et al. in describing a differentiated underlying structure of emotion and cognition processes in early childhood while also extending these conclusions across samples and across measurement approaches for assessing emotion control. 相似文献
29.
Stuart R. Lipsitz Garrett M. Fitzmaurice Geert Molenberghs & Lue Ping Zhao 《Journal of the Royal Statistical Society. Series C, Applied statistics》1997,46(4):463-476
Patients infected with the human immunodeficiency virus (HIV) generally experience a decline in their CD4 cell count (a count of certain white blood cells). We describe the use of quantile regression methods to analyse longitudinal data on CD4 cell counts from 1300 patients who participated in clinical trials that compared two therapeutic treatments: zidovudine and didanosine. It is of scientific interest to determine any treatment differences in the CD4 cell counts over a short treatment period. However, the analysis of the CD4 data is complicated by drop-outs: patients with lower CD4 cell counts at the base-line appear more likely to drop out at later measurement occasions. Motivated by this example, we describe the use of `weighted' estimating equations in quantile regression models for longitudinal data with drop-outs. In particular, the conventional estimating equations for the quantile regression parameters are weighted inversely proportionally to the probability of drop-out. This approach requires the process generating the missing data to be estimable but makes no assumptions about the distribution of the responses other than those imposed by the quantile regression model. This method yields consistent estimates of the quantile regression parameters provided that the model for drop-out has been correctly specified. The methodology proposed is applied to the CD4 cell count data and the results are compared with those obtained from an `unweighted' analysis. These results demonstrate how an analysis that fails to account for drop-outs can mislead. 相似文献
30.
The sociolinguistic modelling of phonological variation and change is almost exclusively based on auditory and acoustic analyses of speech. One phenomenon which has proved elusive when considered in these ways is the variation in postvocalic /r/ in Scottish English. This study therefore shifts to speech production: we present a socioarticulatory study of variation of postvocalic /r/ in CVr (e.g. car) words, using a socially‐stratified ultrasound tongue imaging corpus of speech collected in eastern central Scotland in 2008. Our results show social stratification of /r/ at the articulatory level, with middle‐class speakers using bunched articulations, while working‐class speakers use greater proportions of tongue‐tip and tongue‐front raised variants. Unlike articulatory variation of /r/ in American English, the articulatory variants in our Scottish English corpus are both auditorily distinct from one another, and correlate with strong and weak ends of an auditory rhotic continuum, which also shows clear social stratification. 相似文献