Therapeutic Hypothermia: Quantification of the Transition of Core Body Temperature Using the Flexible Mixture Bent‐Cable Model for Longitudinal Data

Hypothermia which is induced by reducing core body temperature is a therapeutic tool used to prevent brain damage resulting from physical trauma. However, all physiological systems begin to slow down due to hypothermia and this can result in increased risk of mortality. Therefore quantification of the transition of core body temperature to early hypothermia is of great clinical interest. Conceptually core body temperature may exhibit an either gradual or abrupt transition. Bent‐cable regression is an appealing statistical tool to model such data due to the model's flexibility and readily interpretable regression coefficients. It handles more flexibly models that traditionally have been handled by low‐order polynomial models (for gradual transition) or piecewise linear changepoint models (for abrupt change). We consider a rat model to quantify the temporal trend of core body temperature primarily to address the question: What is the critical time point associated with a breakdown in the compensatory mechanisms following the start of hypothermia therapy? To this end, we develop a Bayesian modelling framework for bent‐cable regression of longitudinal data to simultaneously account for gradual and abrupt transitions. Our analysis reveals that: (i) about 39% of rats exhibit a gradual transition in core body temperature; (ii) the critical time point is approximately the same regardless of transition type; and (iii) both transition types show a significant increase of core body temperature followed by a significant decrease.     

Another Look at Daily Lotteries

Lotteries in which the winning number was a number receiving the fewest bets were the subject of “A Look at Daily Lotteries” by Kabak and Simonoff (1983). This note corrects some of their results and makes observations on the probability of winning.     

Becoming invisible: The ethics and politics of imperceptibility

This speculative essay examines ‘invisible’ social identities and the processes by which they are manifested and occasionally sought. Using various literary and academic sources, and loosely informed by an unlikely combination of Stoic philosophy and post-structuralist politics, we argue that invisibility is conventionally viewed as undesirable or ‘suffered’ by individuals or groups that are disadvantaged or marginalised within society. Whilst appreciating this possibility, we argue that social invisibility can also be the result of strategies carefully conceived and consciously pursued. We suggest that forms of social invisibility can be acquired by ethically informed personal action as well as by politically informed collective action. In this context, invisibility can be seen as a strategy of escaping from institutionalised and organisational judgements and which presents a challenge to common notions of voice and identity.     

Alcohol Advertising in College Newspapers: A 7-Year Follow-up

Abstract

The authors report on the frequency and nature of alcohol advertisements in a representative sample of college newspapers from 1984/85 and compare these with results of a similar study conducted 7 years earlier, in 1977/78. On average, nearly 24 column inches of space per issùe were devoted to national alcohol advertisements in 1984/85. This represents a significant decrease from an earlier period. The space devoted to national alcohol advertisements, however, still far exceeded that for comparison products (books, soft drinks). Local alcohol advertisements averaged 20 column inches per issue and were somewhat more frequent than in the previous study. The content of the advertisements differed markedly from the messages presented 7 years earlier. Although national alcohol advertisements in 1977/78 frequently ridiculed education and study, none did so in 1984/85, when appeals were to taste and product quality instead. Fantasy themes also were relatively common. Very few national alcohol advertisements featured athletes or group drinking. Sponsorship of campus activities by the alcohol industry, however, had increased since the earlier study. In contrast to national advertisements, many local advertisements consisted of inducements to drink through special offers and happy hours. Some encouraged irresponsible and heavy drinking. Interestingly, alcohol advertisements were just as frequent in papers from states with higher minimum drinking ages and were more frequent in papers from campuses with higher proportions of women students.     

The Problem of Alcohol Advertisements in College Newspapers

Abstract

In a sample of college newspapers, alcohol advertisements made up approximately one-half of all national advertising. Most of these were for beer. In addition, most of the papers also carried local “on sale” alcohol ads. Ads for soft drinks and for books were far less prominent in the sample. Numerous beer ads contained a philosophy inimical to the aims of college education. Study, learning, science, campus organizations, graduation, and even education itself were ridiculed, and beer drinking was substituted for them. These appeals were considered in relation to studies of drinking problems on campus and peer pressures on students to join in the drinking. Campus efforts toward alcohol education were reviewed and outstanding programs singled out. It was suggested that students, faculty, and staff discuss the problem and seek some resolution.