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871.

Background

Centenarians are a growing population in Europe and present significant variability in motor and cognitive functions. The aim of our study was to characterize health status, as well as cognitive and motor functions in a group of Portuguese centenarians. In addition, our study also aimed at analyzing the relationship between cognitive functions and the burden of diseases affecting the elderly.

Methods

Fifty-two centenarians were evaluated using the Mini-Mental State Examination, short version. Walking-related parameters (velocity and time spent in the 3 m walk test), grip strength and number of age-related illnesses were also measured. The relationship between cognitive scores and time spent in the three metre walk test, velocity, grip strength and number of diseases was analysed.

Results

Cognitive scores showed a positive correlation with both handgrip strength and time spent in the three metre walk. In contrast, no association was found between cognitive scores and the presence/absence of disease, walking velocity or number of diseases present.

Conclusions

These results suggest that in centenarians, cognitive functions may be related with motor functions.
  相似文献   
872.

Background

A low urine pH is a characteristic metabolic feature of metabolic syndrome and type 2 diabetes. The purpose of the current study was to investigate the effects of a 12-week home-based bench step exercise on the urine pH status of elderly female subjects.

Methods

The current study is a secondary analysis of a randomized controlled trial (RCT) in which 59 postmenopausal female subjects were randomized to either the exercise group (n?=?29) or the control group (n?=?30). The subjects in the exercise group were instructed to perform home-based exercises using a bench step at the anaerobic threshold (AT), with a goal of performing ≥140 min/week at home for 12 weeks. The subjects in the control group were instructed to not change their normal lifestyle. Urine was collected after overnight fasting, and the urine pH was measured using a urinary test strip. The inter-group-differences at baseline and the pre-post changes within groups were assessed using the Mann-Whitney U test and Wilcoxon’s signed-rank test, respectively. Additionally, the difference in the post-intervention urine pH levels of the two groups, adjusted for the pre-intervention values (the estimated effect size) and the precision (95% confidence intervals) were investigated using an analysis of covariance.

Results

The pre-post comparison of the urine pH data using Wilcoxon’s signed-rank test showed a significant increase in the urine pH levels of the exercise group (p?<?0.05); there was no significant change in the urine pH levels of the control group. However, the estimated effect size (0.15) was small and the confidence interval straddled 0 (?0.25–0.55).

Conclusions

Based on the results of the current secondary analysis of an RCT, we could not clearly conclude that exercise has a beneficial effect on the urine pH. Further well-designed RCTs should be conducted to determine whether aerobic exercise is truly able to ameliorate urine acidification.

Trial registration

The study was retrospectively registered in the University Hospital Medical Information Network (UMIN) as “Effect of step exercise on aerobic fitness and progression of atherosclerosis in the elderly” under the registration number UMIN 000026743 (the date of registration: March 28, 2017).
  相似文献   
873.
In this paper, we propose a new partial correlation, the so-called composite quantile partial correlation, to measure the relationship of two variables given other variables. We further use this correlation to screen variables in ultrahigh-dimensional varying coefficient models. Our proposed method is fast and robust against outliers and can be efficiently employed in both single index variable and multiple index variable varying coefficient models. Numerical results indicate the preference of our proposed method.  相似文献   
874.
Research has examined various elements of Twitter; however, no scholarship has explored how sociologists currently use the platform. This empirically driven paper explores how individuals that self-identify as sociologists on Twitter use the popular micro-blogging social media site. A total of 152,977 tweets from Twitter profiles of 130 sociologists were collected and examined using qualitative media analysis. The potential use of Twitter allows the sociologist to become both the generator and interlocutor of dialogue with publics. We frame our data analysis and discussion around the core theme of expertise - namely, the role that expertise plays in the use of Twitter by sociologists. Our findings indicate that when sociologists used Twitter as sociologists (i.e., drawing upon their stated research expertise) little direct engagement with publics occurred. Thus, while sociologists appear to be using Twitter as a space for public sociology, the use of this interactive platform is mostly limited to the generation of content, a finding consistent with Burawoy’s traditional form of public sociology. Suggestions for future research are noted.  相似文献   
875.
In response to the system for regulating research with human subjects, researchers have raised two apparently contradictory concerns: that IRBs are excessively inconsistent (often raised by biomedical researchers), and that they are excessively standardizing (often raised by qualitative interview researchers). Why does standardization appear as the dominant theme in qualitative researchers’ experiences with their IRBs? And how do qualitative researchers experience standardization in their IRB encounters? We focus on IRBs role as regulatory bureaucracies, which typically rely heavily on standardized communication and decisions to process information and make large numbers of decisions in a timely manner. We explore the role of standardization in IRB regulation of qualitative research in an analysis of semi-structured interviews with 26 qualitative sociologists from six research universities and three liberal arts colleges in the Northeastern United States. In a regulatory regime oriented toward the norms of experimental research, these frictions resulted partly from a lack of appropriate standardized language and decision-templates, but also from the inherent difficulties of applying standardized decisions to work that is unpredictable, unique, and difficult to routinize.  相似文献   
876.
While cognitive sociology is a relatively new area in U.S. sociology, the subfield has a lengthy history in French sociology. Developing a typology based upon the existing literature, we identify three branches of cognitive sociology in France. The first was initiated by Raymond Boudon, one of the scholars most responsible for popularizing the area, who envisioned cognitive sociology as helping delineate the role of beliefs in rational action. Second, another group of researchers seeks to found sociology upon a naturalistic basis, thus drawing upon the disciplines constitutive of cognitive science (e.g., psychology, cognitive neuroscience, and cognitive anthropology). Finally, the third approach to cognitive sociology in France takes inspiration from linguistics as a foundation for sociological investigations. We conclude the paper by discussing the relationship between these three sub-fields and by examining the relationship between French and American cognitive sociologies in order to identify fruitful directions for future research.  相似文献   
877.
Social Network Analysis (SNA) is a sociology based on interaction that visualizes and models relations between actors. Whereas interaction is approached by classical scholars, we had to wait until the 1970s and the birth of computer science to see social networks analysis develop. This article investigates the influence of SNA in France from the 1980s and wonder if there is a French school of SNA? To do so, we first resume social networks history and highlight its contribution to sociology. Second, we analyze the trajectory and profile of five “disciplinary entrepreneurs,” whose role in the field is important as they master three necessary languages for SNA: English, Mathematics and Computer Science. Third, in order to put back those individuals in their social structures, we cross SNA with the different French sociological tradition(s) (according to topics and methods). Last, we wonder if the institutionalization process succeeded in the creation of institutions from which a French SNA would be able to expand?  相似文献   
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