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91.
随着中国保险业的迅猛发展,保险核算在一国经济中变得越来越重要。越来越频繁发生的自然灾害、恐怖袭击等造成的巨大损失对联合国国民账户体系(93SNA)推荐的非寿险服务产出核算产生重大冲击,严格按照93SNA算法计算保险服务价值会导致荒谬的结果。首先本文介绍了国际上几种主要的改进方法,对每种方法的优缺点进行了深入分析。这些方法对我国改善保险核算,尤其是非寿险服务产出核算具有重要的启示意义。其次运用广东省(不含深圳)保险业的数据和期望法对06、07年的总产出进行计算,构建预测模型,并比较分析计算的结果。最后,本文提出对改进我国保险核算的建议。 相似文献
92.
93.
A Bayesian discovery procedure 总被引:1,自引:0,他引:1
Michele Guindani Peter Müller Song Zhang 《Journal of the Royal Statistical Society. Series B, Statistical methodology》2009,71(5):905-925
Summary. We discuss a Bayesian discovery procedure for multiple-comparison problems. We show that, under a coherent decision theoretic framework, a loss function combining true positive and false positive counts leads to a decision rule that is based on a threshold of the posterior probability of the alternative. Under a semiparametric model for the data, we show that the Bayes rule can be approximated by the optimal discovery procedure, which was recently introduced by Storey. Improving the approximation leads us to a Bayesian discovery procedure, which exploits the multiple shrinkage in clusters that are implied by the assumed non-parametric model. We compare the Bayesian discovery procedure and the optimal discovery procedure estimates in a simple simulation study and in an assessment of differential gene expression based on microarray data from tumour samples. We extend the setting of the optimal discovery procedure by discussing modifications of the loss function that lead to different single-thresholding statistics. Finally, we provide an application of the previous arguments to dependent (spatial) data. 相似文献
94.
We propose a new cure model for survival data with a surviving or cure fraction. The new model is a mixture cure model where
the covariate effects on the proportion of cure and the distribution of the failure time of uncured patients are separately
modeled. Unlike the existing mixture cure models, the new model allows covariate effects on the failure time distribution
of uncured patients to be negligible at time zero and to increase as time goes by. Such a model is particularly useful in
some cancer treatments when the treat effect increases gradually from zero, and the existing models usually cannot handle
this situation properly. We develop a rank based semiparametric estimation method to obtain the maximum likelihood estimates
of the parameters in the model. We compare it with existing models and methods via a simulation study, and apply the model
to a breast cancer data set. The numerical studies show that the new model provides a useful addition to the cure model literature. 相似文献
95.
96.
The main goal of phase I cancer clinical trials is to determine the highest dose of a new therapy associated with an acceptable level of toxicity for the use in a subsequent phase II trial. The continual reassessment method (CRM) [O’Quigley, J., Pepe, M., Fisher, L., 1990. Continual reassessment method: a practical design for phase I clinical trials in cancer. Biometrics 46, 33–48] and escalation with overdose control (EWOC) [Babb, J., Rogatko, A., Zacks, S., 1998. Cancer phase I clinical trials: efficient dose escalation with overdose control. Statist. Med. 17 (10), 1103–1120] are two model-based designs used for phase I cancer clinical trials. A few modifications of the (original) CRM and EWOC have been made by many authors. In this paper, we show how CRM and EWOC can be unified and present a hybrid design. We study the characteristics of the approach of the hybrid design. The comparisons of the three designs (CRM, EWOC, and the hybrid design) are presented by convergence rates and overdose proportions. The simulation results show that the hybrid design generally has faster convergence rates than EWOC and smaller overdose proportions than CRM, especially when the true maximum tolerated dose (MTD) is above the mid-level of the dose range considered. The performance of these three designs is also evaluated in terms of sensitivity to outliers. 相似文献
97.
中国城市化与生态环境协调发展预警系统研究 总被引:5,自引:0,他引:5
本文构建了城市化与生态环境协调发展预警指标体系,并对1991~2010年中国城市化与生态环境的协调度进行了测算及预测,根据协调度建立了预警系统,并对90年代以来中国城市化与生态环境的协调发展进行了分析。结果表明,2007年以来,中国的生态环境不断恶化,城市化与生态环境的协调度不断下降,保护生态环境成为城市化进程中的重要问题。 相似文献
98.
Yanwei Zhang 《Statistics and Computing》2013,23(6):743-757
The Tweedie compound Poisson distribution is a subclass of the exponential dispersion family with a power variance function, in which the value of the power index lies in the interval (1,2). It is well known that the Tweedie compound Poisson density function is not analytically tractable, and numerical procedures that allow the density to be accurately and fast evaluated did not appear until fairly recently. Unsurprisingly, there has been little statistical literature devoted to full maximum likelihood inference for Tweedie compound Poisson mixed models. To date, the focus has been on estimation methods in the quasi-likelihood framework. Further, Tweedie compound Poisson mixed models involve an unknown variance function, which has a significant impact on hypothesis tests and predictive uncertainty measures. The estimation of the unknown variance function is thus of independent interest in many applications. However, quasi-likelihood-based methods are not well suited to this task. This paper presents several likelihood-based inferential methods for the Tweedie compound Poisson mixed model that enable estimation of the variance function from the data. These algorithms include the likelihood approximation method, in which both the integral over the random effects and the compound Poisson density function are evaluated numerically; and the latent variable approach, in which maximum likelihood estimation is carried out via the Monte Carlo EM algorithm, without the need for approximating the density function. In addition, we derive the corresponding Markov Chain Monte Carlo algorithm for a Bayesian formulation of the mixed model. We demonstrate the use of the various methods through a numerical example, and conduct an array of simulation studies to evaluate the statistical properties of the proposed estimators. 相似文献
99.
The general Gauss–Markov model, Y = Xβ + e, E(e) = 0, Cov(e) = σ 2 V, has been intensively studied and widely used. Most studies consider covariance matrices V that are nonsingular but we focus on the most difficult case wherein C(X), the column space of X, is not contained in C(V). This forces V to be singular. Under this condition there exist nontrivial linear functions of Q′Xβ that are known with probability 1 (perfectly) where ${C(Q)=C(V)^\perp}$ . To treat ${C(X) \not \subset C(V)}$ , much of the existing literature obtains estimates and tests by replacing V with a pseudo-covariance matrix T = V + XUX′ for some nonnegative definite U such that ${C(X) \subset C(T)}$ , see Christensen (Plane answers to complex questions: the theory of linear models, 2002, Chap. 10). We find it more intuitive to first eliminate what is known about Xβ and then to adjust X while keeping V unchanged. We show that we can decompose β into the sum of two orthogonal parts, β = β 0 + β 1, where β 0 is known. We also show that the unknown component of X β is ${X\beta_1 \equiv \tilde{X} \gamma}$ , where ${C(\tilde{X})=C(X)\cap C(V)}$ . We replace the original model with ${Y-X\beta_0=\tilde{X}\gamma+e}$ , E(e) = 0, ${Cov(e)=\sigma^2V}$ and perform estimation and tests under this new model for which the simplifying assumption ${C(\tilde{X}) \subset C(V)}$ holds. This allows us to focus on the part of that parameters that are not known perfectly. We show that this method provides the usual estimates and tests. 相似文献
100.
This paper focuses on a novel method of developing one-sample confidence bands for survival functions from right censored data. The approach is model-based, relying on a parametric model for the conditional expectation of the censoring indicator given the observed minimum, and derives its strength from easy access to a good-fitting model among a plethora of choices available for binary response data. The substantive methodological contribution is in exploiting a semiparametric estimator of the survival function to produce improved simultaneous confidence bands. To obtain critical values for computing the confidence bands, a two-stage bootstrap approach that combines the classical bootstrap with the more recent model-based regeneration of censoring indicators is proposed and a justification of its asymptotic validity is also provided. Several different confidence bands are studied using the proposed approach. Numerical studies, including robustness of the proposed bands to misspecification, are carried out to check efficacy. The method is illustrated using two lung cancer data sets. 相似文献