ABSTRACT‘Intra-EU mobility’ from new member states provides a governance challenge to European countries like the Netherlands. Freedom of movement within the EU enables mobility but also has important social consequences at the urban level in particular. This article discusses to what extent local, national and European governments have interacted in the governance of ‘intra-EU movement’ and how this has affected their policies regarding migrants from Central and Eastern Europe in particular. Focusing on the Dutch case, including the cities of The Hague and Rotterdam, this article shows a development from a decoupled relationship, to localist governance and only recently evidence of emerging ‘multilevel governance’. Speaking to the broader literature on multilevel governance, this article firstly shows that in spite of its broad theoretical application, multilevel governance should be seen as one of the varied types of governance in a multilevel setting. And secondly, it shows how and why local governments can play a key role in the bottom-up development of governance in a multilevel setting. 相似文献
We explore from a time-use perspective how private use of computers and the Internet [information and communications technologies (ICTs)] is transforming everyday life. Data from the Swedish 2010–2011 Time-Use Survey reflect a situation in which Internet use has spread widely and become routine for many. Using covariate analysis, we analyse differences in general time use between four groups of ICT users ranging from non-users to heavy users. The theoretical departure point is a nuanced discussion of the time-displacement concept. Results indicate that private time spent using ICTs is associated primarily with individuals’ available free time, that is, elastic relative to time for paid work (i.e. contracted time). Heavy ICT users spend more time on activities carried out alone, are more home centred, and less mobile. Heavy use is associated with somewhat less committed time spent, for example, on maintenance work or taking care of children. Regarding personal time, time for meals is negatively related to heavy use, while night-time sleep is unaffected. Concerning free time, heavy use takes time from sports and outdoor recreation, but has no effect on offline media use, entertainment and cultural activities, or reading. Heavy use does not affect time spent on social activities, for example, for social interaction with family and friends or time spent on voluntary associations. Observed differences become significant at certain thresholds of ICT-related time use, involving heavy users who spend one hour or more on computers and the Internet every day. 相似文献
Although adolescents often seem to improve in their functioning during residential care, there still is little knowledge on what factors are important in achieving these changes. The present study aims to identify the care factors that are important for adolescents’ behavior change during secure residential care. We conducted in-depth interviews with eight adolescents, their parents, eight group care workers and seven teachers concerning their in-care experiences. Both adolescents and parents commonly attributed changes during secure residential care to the treatment environment. Group care workers and teachers did not have a clear, consistent view on the treatment aspects causing positive change with the adolescents. According to the adolescents, good professionals apply a fine balance between rules and freedom, show empathy and are available for support. The view of parents corresponds to this image. Although group care workers are perceived as available for support, adolescents tend to make little use of this help if they experience personal problems during care. The results highlight the importance of responsiveness of secure residential care professionals to the needs and perspectives of adolescents and parents. 相似文献
This study aimed at analysing associations among housing type, neighbourhood safety behaviour, self-rated health (SRH), psychological well-being and unhealthy days in the general population. From 2004 to 2013, 90,845 Swedes completed a questionnaire about their health, number of days with poor health, psychological well-being, housing type, and whether they refrained from going out based on perception of neighbourhood safety. People not living in private housing and those who did not go out for safety reasons reported lower SRH and psychological well-being and higher frequency of recent unhealthy days and days without work capacity due to poor health. 相似文献
Much scholarship on boundary-making focuses on dyadic relationships between “us” and “them.” Yet the presence of multiple categories within societies allows for complex interactions among more than two potentially relevant groups. To capture this phenomenon and its dynamics better, we develop the concept of leveraging: the strategic manipulation of social distance among three or more constructed groups for political gain. The use of one group as a lever against another may involve stigmatizing or elevating categories of people along boundaries of race, ethnicity, national origin, religion, gender, class, sexual orientation, or other salient social markers. We theorize these processes and identify the motivations of the initiators of leveraging as well as the range of possible responses to it. We use a pair of empirical case studies drawn from contemporary Europe and additional examples from other settings to demonstrate the relevance of the concept. Conceptualizing leveraging both improves our scholarly understanding of group-making processes and offers political actors tools for interpreting and responding to a common set of strategic practices.
In oncology/hematology early phase clinical trials, efficacies were often observed in terms of response rate, depth, timing, and duration. However, the true clinical benefits that eventually support registrational purpose are progression-free survival (PFS) and/or overall survival (OS), the follow-up of which are typically not long enough in early phase trials. This gap imposes challenges in strategies for late phase drug development. In this article, we tackle the question by leveraging published study to establish a quantitative link between early efficacy outcomes and late phase efficacy endpoints. We used solid tumor cancer as disease model. We modeled the disease course of a RECISTv1.1 assessed solid tumor with a continuous Markov chain (CMC) model. We parameterize the transition intensity matrix of a CMC model based on published aggregate-level summary statistics, and then simulate subject-level time-to-event data. The simulated data is shown to have good approximation to published studies. PFS and/or OS could be predicted with the transition intensity matrix modified given clinical knowledge to reflect various assumptions on response rate, depth, timing, and duration. The authors have built a R shiny application named PubPredict, the tool implements the algorithm described above and allows customized features including multiple response levels, treatment crossover and varying follow-up duration. This toolset has been applied to advise phase 3 trial design when only early efficacy data are available from phase 1 or 2 studies. 相似文献
The present study examined what kinds of patterns of task‐values adolescents show, and whether these patterns predict their educational and occupational expectations and school track. Six hundred and fourteen adolescents were examined twice before their transition to secondary education and once thereafter. The clustering‐by‐cases analyses identified 6 groups: (1) those who placed a high value on all school subjects, (2) those who did not value any of the subjects, (3) those who valued Finnish and social sciences, (4) those who valued in particular practical and art subjects, (5) those who valued only practical and art subjects, and (6) those who especially valued mathematics and science. The patterns of task‐values also predicted adolescents' occupational and educational expectations. 相似文献
How do global issue constructions serve as resources for actors engaged in domestic political contention, and what does the appropriation of global ideas by domestic actors imply about the spread of global culture? To contribute to knowledge about conflict‐based diffusion of global ideas, we examine the histories of global constructions of indigenous rights and national debates about indigenous rights in Fiji and Tanzania. While global models of indigenous rights emphasize self‐determination for nondominant, culturally distinct groups at risk from the nation‐state, advocates for indigenization policies in Fiji and Tanzania have argued for state policies to entrench political and economic rights for majority or near‐majority groups that were well integrated into the nation‐state. Although transnationally connected indigenous rights organizations have a greater presence in Tanzania than in Fiji, actors in Fiji remain more engaged with changes in international indigenous rights discourse than their counterparts in Tanzania. This difference reflects variations in the leverage global culture offered in the two cases because of its externality to national political debates. In Fiji, actors appropriated global culture as a means to internationalize a domestic dispute, while in Tanzania the impetus for indigenization came from global economic pressures. Our findings imply that conflict‐based diffusion concentrates agency with respect to the use of global legal discourses in domestic actors rather than the globally connected actors and experts who carry global culture in consensus‐based diffusion. 相似文献