DEVELOPMENT OF PRACTICE

In this paper it is described how the work of the Balay Rehabilitation Centre in the Philippines has changed over time as the political and human rights conditions of the country's affected areas have changed. Balay's psychosocial rehabilitation programmes address the needs of individuals and communities and offer support and healing. Originally Balay focused on individual and family-level psychological and social intervention in accordance with clinical diagnoses; however, as the political and human rights situation of the Philippines changed and large numbers of people became victims of trauma and displacement the intervention strategies changed. Balay became increasingly interested in assisting communities to become empowered to participate in their own healing and the frameworks of community research and participatory action research (PAR) are now being explored by Balay as valid methods of integrating research with rehabilitation activities on the community level.     

The Diffusion and Innovation of Muslim Organizations in Denmark

Since 1965, the latest immigration to Denmark has not only brought new groups to the country but also resulted in new organizations, associations and movements established by people with Muslim background. In order to understand this extension and renewal of Danish civil society I distinguish between forms of organizations and forms of diffusion. The outcome of the analysis reveals four distinct clusters of Muslim organizations in Denmark: The first generation of Muslim associations was characterized by centralized state sponsored organizations, governed and financed by Arab countries and Turkey. The second generation of Muslim organizations took the form of transnational social movements and were often set up as a counterpart to the state sponsored organizations. The third wave of organization building, the so-called homegrown organizations, tried to unite Muslims in Denmark and worked for a dialog with the Danish majority. Most of the Muslim youth organizations belong to this category. However, some political Islamic youth organizations and networks have chosen an alternative strategy that challenges mainstream Danish institutions and values. The reaction of the government has been to tone down cooperation with representatives from the immigrant population and especially representatives from the Muslim minority.     

A Trichloroethylene Risk Assessment Using a Monte Carlo Analysis of Parameter Uncertainty in Conjunction with Physiologically-Based Pharmacokinetic Modeling

A Monte Carlo simulation is incorporated into a risk assessment for trichloroethylene (TCE) using physiologically-based pharmacokinetic (PBPK) modeling coupled with the linearized multistage model to derive human carcinogenic risk extrapolations. The Monte Carlo technique incorporates physiological parameter variability to produce a statistically derived range of risk estimates which quantifies specific uncertainties associated with PBPK risk assessment approaches. Both inhalation and ingestion exposure routes are addressed. Simulated exposure scenarios were consistent with those used by the Environmental Protection Agency (EPA) in their TCE risk assessment. Mean values of physiological parameters were gathered from the literature for both mice (carcinogenic bioassay subjects) and for humans. Realistic physiological value distributions were assumed using existing data on variability. Mouse cancer bioassay data were correlated to total TCE metabolized and area-under-the-curve (blood concentration) trichloroacetic acid (TCA) as determined by a mouse PBPK model. These internal dose metrics were used in a linearized multistage model analysis to determine dose metric values corresponding to 10^-6 lifetime excess cancer risk. Using a human PBPK model, these metabolized doses were then extrapolated to equivalent human exposures (inhalation and ingestion). The Monte Carlo iterations with varying mouse and human physiological parameters produced a range of human exposure concentrations producing a 10^-6 risk.     

The impact of a respite volunteer ‘buddy’ programme on behavioural and psychological well-being in young carers

Young carers often face a great amount of emotional burden and have high practical and social responsibilities. The role of being a young carer is associated with behavioural, developmental, physical and psychosocial problems that may not only affect the individual in childhood but also in adulthood. The aim of this study was to investigate the effect of a Danish respite volunteer programme called The Buddies for Children and Youngsters Programme on young carers' (n = 49; aged 6–16) social–emotional functioning. A pre–post-design was applied, and data were collected through the parent version of the strengths and difficulties questionnaire (SDQ), here with an impact supplement at baseline and at the end of the programme (after 4 months). The programme showed a positive impact on emotional symptoms, hyperactivity symptoms, conduct problems, peer problems, prosocial aspects and impact aspects, with mean differences values of −2.50 (p = .000), −0.62 (p = .271), −1.18 (p = .000), −0.74 (p = .008), 0.62 (p = .004) and −0.88 (p = .007), respectively. Furthermore, a large effect was found for the total difficulties score: −5.03 (p = .000). In conclusion, the programme seems promising considering its effect on young carers' social–emotional functioning. However, future research should include comparative studies with a longer duration.     

A Bayesian meta-analysis of infants’ ability to perceive audio–visual congruence for speech

This paper quantifies the extent to which infants can perceive audio–visual congruence for speech information and assesses whether this ability changes with native language exposure over time. A hierarchical Bayesian robust regression model of 92 separate effect sizes extracted from 24 studies indicates a moderate effect size in a positive direction (0.35, CI [0.21: 0.50]). This result suggests that infants possess a robust ability to detect audio–visual congruence for speech. Moderator analyses, moreover, suggest that infants’ audio–visual matching ability for speech emerges at an early point in the process of language acquisition and remains stable for both native and non-native speech throughout early development. A sensitivity analysis of the meta-analytic data, however, indicates that a moderate publication bias for significant results could shift the lower credible interval to include null effects. Based on these findings, we outline recommendations for new lines of enquiry and suggest ways to improve the replicability of results in future investigations.