A Two-Dimensional Two-Layered Societal Index of Interpersonal Destructiveness: Internal Consistency Analysis

Although the World Health Assembly emphasized as early as in 1996 the need for violence prevention, there is still no generally accepted index for interpersonal destructiveness in a society. Hereby we propose a Societal Index of Interpersonal Destructiveness (SIID) that could be used to compare interpersonal violence in different societies. SIID is a composite of two sub-indices: (1) Index of Interpersonal Destructiveness Prerequisites, and (2) Index of Interpersonal Destructiveness Consequences. This study addresses the construction and internal consistency analysis of SIID. The Indices for periods 1989–1993, 1994–1999, 1999–2004, 2005–2007 and 2008–2010 are computed and for 28–48 countries, depending on availability of high quality and comparative data across time. We conclude that SIID has considerable potential as an internally consistent yardstick for evaluating and comparing the level of interpersonal destructiveness of societies worldwide.     

Emotion Recognition in Nonverbal Face-to-Face Communication

The perception of emotional facial expressions may activate corresponding facial muscles in the receiver, also referred to as facial mimicry. Facial mimicry is highly dependent on the context and type of facial expressions. While previous research almost exclusively investigated mimicry in response to pictures or videos of emotional expressions, studies with a real, face-to-face partner are still rare. Here we compared facial mimicry of angry, happy, and sad expressions and emotion recognition in a dyadic face-to-face setting. In sender-receiver dyads, we recorded facial electromyograms in parallel. Senders communicated to the receivers—with facial expressions only—the emotions felt during specific personal situations in the past, eliciting anger, happiness, or sadness. Receivers mostly mimicked happiness, to a lesser degree, sadness, and anger as the least mimicked emotion. In actor-partner interdependence models we showed that the receivers’ own facial activity influenced their ratings, which increased the agreement between the senders’ and receivers’ ratings for happiness, but not for angry and sad expressions. These results are in line with the Emotion Mimicry in Context View, holding that humans mimic happy expressions according to affiliative intentions. The mimicry of sad expressions is less intense, presumably because it signals empathy and might imply personal costs. Direct anger expressions are mimicked the least, possibly because anger communicates threat and aggression. Taken together, we show that incidental facial mimicry in a face-to-face setting is positively related to the recognition accuracy for non-stereotype happy expressions, supporting the functionality of facial mimicry.     

Adaptive designs for pivotal trials: discussion points from the PSI Adaptive Design Expert Group

The Committee for Medicinal Products for Human Use (CHMP) is currently preparing a guideline on 'methodological issues in confirmatory clinical trials with flexible design and analysis plan'. PSI (Statisticians in the Pharmaceutical Industry) sponsored a meeting of pharmaceutical statisticians with an interest in the area to share experiences and identify potential opportunities for adaptive designs in late-phase clinical drug development. This article outlines the issues raised, resulting discussions and consensus views reached. Adaptive designs have potential utility in late-phase clinical development. Sample size re-estimation seems to be valuable and widely accepted, but should be made independent of the observed treatment effect where possible. Where unblinding is necessary, careful consideration needs to be given to preserving the integrity of the trial. An area where adaptive designs can be particularly beneficial is to allow dose selection in pivotal trials via adding/dropping treatment arms; for example, combining phase II and III of the drug development program. The more adaptations made during a late-phase clinical trial, the less likely that the clinical trial would be considered as a confirmatory trial. In all cases it would be advisable to consult with regulatory agencies at the protocol design stage. All involved should remain open to scientifically valid opportunities to improve drug development.     

Selection,Alignment, and Their Interplay: Origins of Lifestyle Homogamy in Couple Relationships

The present study examines different processes leading to lifestyle homogamy in married and cohabiting couples using data from the German Socioeconomic Panel (n = 3,490 couples). The analyses first suggest that alignment over time promotes homogamy of leisure‐related lifestyles, especially with respect to action‐oriented activities. However, intermediate stages in the life course (i.e., phases of active parenting and labor force participation) tend to inhibit alignment, whereas cues indicating a high‐quality match (e.g., educational homogamy and being in a long‐term or a marital relationship) promote alignment. Second, we find evidence for selection effects in that not only homogamy but also convergence of lifestyles over time may increase couples' resilience to relationship breakup.     

Development of Life Satisfaction in Old Age: Another View on the "Paradox'

Empirical evidence of no age-related decline in life satisfaction (LS) in old age contrasts with frequently observed declines in the objective quality of elder people's lives and has therefore been labelled a "paradox' and interpreted in terms of stability of LS in the respective gerontological discussion. However, as this evidence was mainly derived from cross-sectional age group comparisons, it does neither clearly indicate the absence of age-related mean level change, nor intra-individual stability of LS. Thus, the development of LS in middle and late adulthood was analysed longitudinally by using data from the German Socio-Economic Panel. Based on single item measures of LS across 16 repeated panel waves with one per annum (1984–1999), autoregressive (quasi-Markov) structural equation models were used to estimate true score variances and intra-individual true score stability in one-year intervals. Research questions concerned (a) "monotonic' stability and variance in a subsample of old respondents (born before 1925) as compared to the total sample and (b) change in stability and variances in old age. Results indicate high "monotonic' true score stability of LS over the whole adult life span, whereas mean levels declined slightly in old age. No striking evidence for age-related changes in variance or stability was found.     

Investment and Competition Policy in the WTO: Issues for Developing Countries

This article uses the case of trade‐related investment measures (TRIMs) to examine the liberalisation of investment and its potential impact on developing countries. Very few developing countries actually use TRIMs to any appreciable degree, but, when taken in conjunction with the broader liberalisation of investment, the 1994 TRIMs Agreement has significant implications that will constrain governments’ policy options and require issues of competition policy to be addressed. Multilateral competition policy would be difficult to agree and implement and the article considers alternative strategies that developing countries could adopt.