Risk Assessment for Carcinogens Under California''s Proposition 65

Risk assessments for carcinogens are being developed through an accelerated process in California as a part of the state's implementation of Proposition 65, the Safe Drinking Water and Toxic Enforcement Act. Estimates of carcinogenic potency made by the California Department of Health Services (CDHS) are generally similar to estimates made by the U.S. Environmental Protection Agency (EPA). The largest differences are due to EPA's use of the maximum likelihood estimate instead of CDHS' use of the upper 95% confidence bounds on potencies derived from human data and to procedures used to correct for studies of short duration or with early mortality. Numerical limits derived from these potency estimates constitute "no significant risk" levels, which govern exemption from Proposition 65's discharge prohibition and warning requirements. Under Proposition 65 regulations, lifetime cancer risks less than 10(-5) are not significant and cumulative intake is not considered. Following these regulations, numerical limits for a number of Proposition 65 carcinogens that are applicable to the control of toxic discharges are less stringent than limits under existing federal water pollution control laws. Thus, existing federal limits will become the Proposition 65 levels for discharge. Chemicals currently not covered by federal and state controls will eventually be subject to discharge limitations under Proposition 65. "No significant risk" levels (expressed in terms of daily intake of carcinogens) also trigger warning requirements under Proposition 65 that are more extensive than existing state or federal requirements. A variety of chemical exposures from multiple sources are identified that exceed Proposition 65's "no significant risk" levels.     

Tests of the causal directions of global — Life facet satisfaction relationships

Previous research generally has supported multiple discrepancies theory (MDT) of the processes by which individuals arrive at judgments of satisfaction with various aspects of their lives as well as with life overall. However, the nature of possible causal relationships between overall and life facet satisfaction has been ignored. The purpose of this study was to extend MDT by testing alternative theoretical models which specified Bottom-up, Top-Down, and Bidirectional relationships between overall life satisfaction and satisfaction with 11 life facets in a sample of 1354 U.S. college students. Results most strongly favored the Bidirectional model in which the overall — life facet satisfaction relationship varied across life domains. The need to identify boundary conditions which determine the direction of the overall — life facet satisfaction relationship is discussed.     

Responding to environmental change in longshoring: Four north American experiences

In longshoring, technological change, expanding competition among ports, and the development of lower cost work forces induced a major restructuring of dock operations. This paper focuses on collective bargaining responses to environmental change and the interplay between those responses, government intervention, the law, and market forces. Four coastal regions in the United States and Canada are studied to gain a broad perspective in two jurisdictions with somewhat differing approaches to government intervention and labor law. Market pressures have become a dominant force, altering the need for and nature of government intervention, and accommodation to change seems most appropriate in today’s highly competitive marketplace. We are indebted to those we interviewed: Brian Ciccozzi, D. P. (Don) Garcia, Terry Lane, Arnold E. Masters, Gene Vrana, Greg Storey, Joe Weiler, and R. V. Wilds. We greatly appreciate the comments of Vitor Marciano, Yoni Reshef, and an anonymous referee, as well as the support of the Social Sciences and Humanities Research Council and the Rice Fellowship. I thank the Oakland University Research Committee for grant support.     

The poisson-inverse gaussian disiribuiion as a model for species abundance

An inverse Gaussian mixture of Poisson distributions(the P-IG distribution) is considered as a model for species abundance data,, Minimum chi-square and maximum likelihood methods of estimation for the zero-truncated P-IG distribution are developed, Ihe performance of the P-IG distribution is illustrated and discussed for several well-known sets of insect abundance data.     

The Opportunities and Constraints to Collaboration in Public Sector Management

Public Organization Review - This article synthesizes current insights about the opportunities and constraints to collaborative public management. Despite the swath of research on...     

Personality Disorders Among Pathological Gamblers

The objective of this study was to investigate the prevalence of DSM-III-R diagnostic categories of personality disorders in pathological gamblers and to highlight the possible association between such disorders, psychological distress and selected forms of gambling. The Personality Disorders Questionnaire-Revised and a battery of psychometric measures were administered to a sample of 82 consecutive admissions to a behavioral treatment program for gambling problems at an impulse control disorders research unit in Sydney, Australia. Seventy-three percent of subjects were male. The total sample reported having gambled a mean of 15 years of which, on average, the last 6.4 years were associated with problems. Results indicated that the majority of subjects met diagnostic criteria for at least one Personality Disorder (93%), with an average of 4.6 personality disorders per subject. The majority of gamblers evidenced personality disorders from the Cluster B grouping with particularly high rates of borderline, histrionic, and narcissistic personality disorders which were found to be associated with high levels of impulsivity and affective instability. Antisocial personality disorder and narcissistic personality disorder were both found to be possible mediators of the severity of the problem gambling behaviours.     

Online patient feedback as a safety valve: An automated language analysis of unnoticed and unresolved safety incidents

Safety reporting systems are widely used in healthcare to identify risks to patient safety. But, their effectiveness is undermined if staff do not notice or report incidents. Patients, however, might observe and report these overlooked incidents because they experience the consequences, are highly motivated, and independent of the organization. Online patient feedback may be especially valuable because it is a channel of reporting that allows patients to report without fear of consequence (e.g., anonymously). Harnessing this potential is challenging because online feedback is unstructured and lacks demonstrable validity and added value. Accordingly, we developed an automated language analysis method for measuring the likelihood of patient-reported safety incidents in online patient feedback. Feedback from patients and families (n = 146,685, words = 22,191,427, years = 2013–2019) about acute NHS trusts (hospital conglomerates; n = 134) in England were analyzed. The automated measure had good precision (0.69) and excellent recall (0.98) in identifying incidents; was independent of staff-reported incidents (r = −0.04 to 0.19); and was associated with hospital-level mortality rates (z = 3.87; p < 0.001). The identified safety incidents were often reported as unnoticed (89%) or unresolved (21%), suggesting that patients use online platforms to give visibility to safety concerns they believe have been missed or ignored. Online stakeholder feedback is akin to a safety valve; being independent and unconstrained it provides an outlet for reporting safety issues that may have been unnoticed or unresolved within formal channels.     

Measuring Knowledge,Attitudes and Behaviours Concerning Sustainable Development among Tenth Grade Students in Manitoba

In this paper we present standardized measures of tenth grade students’ knowledge, attitudes and behaviours concerning sustainable development as those concepts are understood in the United Nations Educational, Scientific and Cultural Organization, and we test the hypothesis that knowledge and favourable attitudes toward SD lead to favourable behaviours. Using a fairly representative random sample of 1,551 tenth grade students from the province of Manitoba, Canada, we crafted 3 indexes. There is a 20-item Index of Knowledge of SD with a good Cronbach alpha = 0.89, a 15-item Index of Attitudes Favourable Toward SD with alpha = 0.84 and a 15-item Index of Behaviours Favourable Toward SD with an alpha = 0.83. About 21% of the variation in our Behaviours Index scores could be accounted for by our Knowledge Index and Attitudes Index scores.