Recovery and detachment between shifts, and fatigue during a twelve-hour shift

The study investigated the role of recovery and detachment in the break period between two shifts for fatigue in the current shift. A time-based paper-and-pencil diary study was carried out observing sixty-four railway controllers over ten consecutive working shifts. The results demonstrated that fatigue in the current shift was not only affected by recovery and psychological detachment during break phases before a shift, but also by fatigue at shift onset and perceived workload during the shift.     

Regulation and the future of work: The employment relationship as an innovation facilitator

Digital transformation and the reorganization of the firm have given rise to new forms of work that diverge significantly from the standard employment relationship. Advocates of digital disruption suggest that the existing legal framework cannot accommodate “innovative” working templates and business models. This article, however, argues that labour regulation can continue to facilitate innovation, presenting the employment relationship as a flexible instrument, and standard forms of employment as the means of achieving efficiencies and cost advantages. First, they allow for the full exercise of managerial prerogative and attendant internal flexibility in workforce deployment, and, second, they constitute an effective device to deliver training and develop skills.     

The role of the board in shaping foundations’ strategy: an empirical study

This paper investigates the relationships of the choice of philanthropic strategy with board capital (diversity and networks), board activities (board processes, internal board committees, and board effectiveness), and CEO leadership. Using a sample of 110 Italian foundations, the research shows that board processes have the strongest positive association with an evolved strategic approach to philanthropic institutional grant-giving, while board diversity and strong CEO leadership are associated with the strategic approach only under certain conditions. In particular, good governance processes (e.g., training the board, self-evaluation of trustees, setting the stage for effective board and committee meetings, implementing control software, and steering meetings to improve the board’s analysis) are positively associated with evolved strategic approaches to philanthropy (e.g., signaling other funders for the best grantees, improving the performance of grant recipients, and advancing selected social fields’ state of knowledge and practice).     

Models of Neurotoxicity: Extrapolation of Benchmark Doses in Vitro

In risk assessment, no observed exposure level (NOAEL) and benchmark dose (BMD) are usually derived either from epidemiological studies in humans or from animal experiments. In many in vitro studies, concentration-effect/response curves have been analyzed using different mathematical models finalized to the identification of EC50. In the present article, we propose a model to fit dose-response curves in vitro. The BMD approach has been used to compare the cell viability (MIT assay) of different rat (C6 and PC12, glial and neuronal, respectively) and human cell lines (D384 and SK-N-MC, glial and neuronal, respectively) after 24-hour exposure to the following neurotoxic substances: manganese chloride (MnCl2), methyl-mercury (Me-Hg), and the enantiomers of styrene oxide (SO). For all rat and human cell lines, the potency of the examined compounds was: MnCl2 < S-SO < R-SO < Me-Hg. A preliminary comparison with in vivo toxicity data for these substances gave rise to consistent results. Whereas a reasonable agreement between in vitro and in vivo data has been found for Mn and styrene oxide, a wide scatter of LOAEL has been reported for Me-Hg and these appear to be either much higher or lower than the BMD for the MIT assay we observed in vitro.     

A Structural Model of Government Formation

In this paper we estimate a bargaining model of government formation in parliamentary democracies. We use the estimated structural model to conduct constitutional experiments aimed at evaluating the impact of institutional features of the political environment on the duration of the government formation process, the type of coalitions that form, and their relative stability.     

Statistical concepts of a priori and a posteriori risk classification in insurance

Everyday we face all kinds of risks, and insurance is in the business of providing us a means to transfer or share these risks, usually to eliminate or reduce the resulting financial burden, in exchange for a predetermined price or tariff. Actuaries are considered professional experts in the economic assessment of uncertain events, and equipped with many statistical tools for analytics, they help formulate a fair and reasonable tariff associated with these risks. An important part of the process of establishing fair insurance tariffs is risk classification, which involves the grouping of risks into various classes that share a homogeneous set of characteristics allowing the actuary to reasonably price discriminate. This article is a survey paper on the statistical tools for risk classification used in insurance. Because of recent availability of more complex data in the industry together with the technology to analyze these data, we additionally discuss modern techniques that have recently emerged in the statistics discipline and can be used for risk classification. While several of the illustrations discussed in the paper focus on general, or non-life, insurance, several of the principles we examine can be similarly applied to life insurance. Furthermore, we also distinguish between a priori and a posteriori ratemaking. The former is a process which forms the basis for ratemaking when a policyholder is new and insufficient information may be available. The latter process uses additional historical information about policyholder claims when this becomes available. In effect, the resulting a posteriori premium allows one to correct and adjust the previous a priori premium making the price discrimination even more fair and reasonable.     

On some mixture models based on the Birnbaum-Saunders distribution and associated inference

In this paper, we consider three different mixture models based on the Birnbaum-Saunders (BS) distribution, viz., (1) mixture of two different BS distributions, (2) mixture of a BS distribution and a length-biased version of another BS distribution, and (3) mixture of a BS distribution and its length-biased version. For all these models, we study their characteristics including the shape of their density and hazard rate functions. For the maximum likelihood estimation of the model parameters, we use the EM algorithm. For the purpose of illustration, we analyze two data sets related to enzyme and depressive condition problems. In the case of the enzyme data, it is shown that Model 1 provides the best fit, while for the depressive condition data, it is shown all three models fit well with Model 3 providing the best fit.     

Assessing the pattern of covariance matrices via an augmentation multiple testing procedure

This paper extends the scedasticity comparison among several groups of observations, usually complying with the homoscedastic and the heteroscedastic cases, in order to deal with data sets laying in an intermediate situation. As is well known, homoscedasticity corresponds to equality in orientation, shape and size of the group scatters. Here our attention is focused on two weaker requirements: scatters with the same orientation, but with different shape and size, or scatters with the same shape and size but different orientation. We introduce a multiple testing procedure that takes into account each of the above conditions. This approach discloses a richer information on the data underlying structure than the classical method only based on homo/heteroscedasticity. At the same time, it allows a more parsimonious parametrization, whenever the patterned model is appropriate to describe the real data. The new inferential methodology is then applied to some well-known data sets, chosen in the multivariate literature, to show the real gain in using this more informative approach. Finally, a wide simulation study illustrates and compares the performance of the proposal using data sets with gradual departure from homoscedasticity.