Reference database of hematological parameters for growing and aging rats

The normal hematological values in various phases of the rat life provide a valuable guide to researchers and could be useful for experimental works. However, database information available on the literature are incomplete. Aim: This study aimed to present normal hematological parameters of young and aged rats.

Methods: Male and female rats were distributed into seven experimental groups with 1, 2, 3, 6, 12, 18, and 24 months of age. Blood samples taken from the tails were analyzed. Normal hematological values were determined for each age group.

Results: Rats showed a progressive weight gain with advancing age, predominantly after 3 months of life. With advancing age, differences were found on hematological parameters: some of them showed a progressive rise with age and others did not. Hemoglobin levels and hematocrit did not change while the number of circulating red blood cells suffered slight increase.

Conclusion: The present study determined the normal values for absolute and relative hematological parameters in Wistar rats from 2 to 24 months for male and female rats. The results can be used in studies of effects of aging, feeding, and medications on growing and aging rats.     

Institutional and Demographic Explanations of Women's Employment in 18 OECD Countries, 1975–1999

This study combined demographic and institutional explanations of women's employment, describing and explaining the degree to which mothers in industrialized societies are less likely to be employed than women without children. A large number of cross‐sectional surveys were pooled, covering 18 Organisation for Economic Co‐Operation and Development countries, 192,484 observations, and 305 country‐years between 1975 and 1999. These data were merged with measures of institutional context and analyzed with multilevel logistic regression. The results indicate that, over time, women were increasingly likely to combine motherhood and employment in many, but not all, countries. Both mothers and women without children were more likely to be employed in societies with a large service sector and low unemployment. The employment of women without children was generally unaffected by family policies. Mothers were more likely to be employed in societies with extensive reconciliation policies and limited family allowances.