Correlates of caregiving burden in schizophrenia:A cross-sectional,comparative analysis from India

Schizophrenia is a global mental health issue that has serious implications not only for the person with the diagnosis, but for caregivers as well. In Asian societies, the family tends to be the “natural” caregiver in such situations and the caregiving function is usually shouldered by parents or the spouse. Asian communities tend to be more closely knit, and it would be expected that more social support would be available to those facing distressing circumstances such as managing the demands of a person with mental illness. This study seeks to explore the perceived burden in family caregivers of persons diagnosed with schizophrenia, the coping strategies that come into play, as well as the extent of social support available to them. Standardized instruments were administered to collect data at a teaching cum treatment facility in south India. A quantitative methodology was used to analyze cross-sectional data from 75 primary caregivers of people with a diagnosis of schizophrenia and a reference group of caregivers of patients with general medical ailments. Results indicate higher levels of burden, low social support, and poor coping in the caregivers of people with schizophrenia than the reference group. Implications for intervention with caregivers are also discussed in this article.     

Cubic rank transmuted distributions: inferential issues and applications

In this paper, we introduce a new family of transmuted distributions, the cubic rank transmutation map distribution. This new proposal increases the flexibility of the transmuted distributions enabling the modelling of more complex data such as ones possessing bimodal hazard rates. In order to illustrate the usefulness of the cubic rank transmutation map, we use two well-known lifetime distributions, namely the Weibull and log-logistic models. Several mathematical properties of these new distributions, namely the cubic rank transmuted Weibull distribution and the cubic rank transmuted log-logistic distribution, are derived. Then, the maximum likelihood estimation of the model parameters is described. A simulation study designed to assess the properties of this estimation procedure is then carried out. Finally, applications of the proposed models and their fit are illustrated with some datasets and the corresponding diagnostic analyses are also provided.     

On the hidden truncated bivariate Pareto (IV) model and associated inferential issues

Income and wealth data are typically modelled by some variant of the classical Pareto distribution. Often, in practice, the observed data are truncated with respect to some unobserved covariate. In this paper, a hidden truncation formulation of this scenario is proposed and analysed. For this purpose, a bivariate Pareto (IV) distribution is assumed for the variable of interest and the unobserved covariate. Some important distributional properties of the resulting model as well as associated inferential methods are studied. An example is used finally to illustrate the results developed here. In this case, it is noted that hidden truncation on the left does not result in any new model, but the hidden truncation on the right does. The properties and fit of such a model pose a challenging problem and that is what is focused here in this work.     

An EM type estimation procedure for the destructive exponentially weighted Poisson regression cure model under generalized gamma lifetime

In this paper, we assume the number of competing causes to follow an exponentially weighted Poisson distribution. By assuming the initial number of competing causes can undergo destruction and that the population of interest has a cure fraction, we develop the EM algorithm for the determination of the MLEs of the model parameters of such a general cure model. This model is more flexible than the promotion time cure model and also provides an interesting and realistic interpretation of the biological mechanism of the occurrence of an event of interest. Instead of assuming a particular parametric distribution for the lifetime, we assume the lifetime to belong to the wider class of generalized gamma distribution. This allows us to carry out a model discrimination to select a parsimonious lifetime distribution that provides the best fit to the data. Within the EM framework, a two-way profile likelihood approach is proposed to estimate the shape parameters. An extensive Monte Carlo simulation study is carried out to demonstrate the performance of the proposed estimation method. Model discrimination is carried out by means of the likelihood ratio test and information-based methods. Finally, a data on melanoma is analyzed for illustrative purpose.     

Inference for Type II bivariate Pólya–Aeppli distribution

In this article, we discuss the estimation of model parameters of the Type II bivariate Pólya–Aeppli distribution using the method of moments and the maximum likelihood method. We also compare some interval estimation methods. We then carry out a Monte Carlo simulation study to evaluate the performance of the proposed point and interval estimation methods. Finally, we present an example to illustrate all the inferential methods developed here.     

A skew logistic distribution as an alternative to the model of van Staden and King

The logistic distribution is a simple distribution possessing many useful properties and has been used extensively for analyzing growth. Recently, van Staden and King proposed a quantile-based skew logistic distribution. In this paper, we introduce an alternative skew logistic distribution. We then establish recurrence relations for the computation of the single and product moments of order statistics from the standard skew logistic distribution by using the moments of order statistics from the standard half logistic distribution. These enable an efficient computation of means, variances and covariances of order statistics from the skew logistic distibution for all sample sizes. The results become useful in determining the best linear unbiased estimators of the location and scale paramters of the skew logistic distribution. Finally, we provide an example to illustrate the usefulness of the developed model and then compare its fit with that provided by the model of van Staden and King.     

Order statistics and their concomitants from multivariate normal mean–variance mixture distributions with application to Swiss Markets Data

In this article, by considering a multivariate normal mean–variance mixture distribution, we derive the exact joint distribution of linear combinations of order statistics and their concomitants. From this general result, we then deduce the exact marginal and conditional distributions of order statistics and their concomitants arising from this distribution. We finally illustrate the usefulness of these results by using a Swiss markets dataset.     

Likelihood inference for Type I bivariate Pólya–Aeppli distribution

This article discusses likelihood inference for the Type I bivariate Pólya–Aeppli distribution. The Type I bivariate Pólya–Aeppli distribution was derived by Minkova and Balakrishnan by using compounding with geometric random variables and the trivariate reduction method. They also discussed the moment estimation of the parameters of the Type I bivariate Pólya–Aeppli distribution. Here, we carry out a simulation study to compare the performance of the developed Maximum Likelihood Estimation (MLE) method with the moment estimation. The obtained results show that, through the MLEs require more computational time compared to the moment estimates (MoM), the MLEs perform better, in most of the settings, than the MoM. Finally, we apply the Type I bivariate Pólya–Aeppli model to a real dataset containing the frequencies of railway accidents in two subsequent six-year periods for the purpose of illustration. We also carry out some hypothesis tests using the Wald test statistic. From these results, we conclude that the two variables belong to the same univariate Pólya–Aeppli distribution, but are correlated.     

Multivariate Bayesian U-type asymmetric designs for non parametric response surface prediction under correlated errors

The objective of this paper is to study U-type designs for Bayesian non parametric response surface prediction under correlated errors. The asymptotic Bayes criterion is developed in terms of the asymptotic approach of Mitchell et al. (1994 Mitchell, T., Sacks, J., Ylvisaker, D. (1994). Asymptotic Bayes criteria for nonparametric response surface design. Ann. Stat. 22:634–651.[Crossref], [Web of Science ®] , [Google Scholar]) for a more general covariance kernel proposed by Chatterjee and Qin (2011 Chatterjee, K., Qin, H. (2011). Generalized discrete discrepancy and its applications in experimental designs. J. Stat. Plann. Inference 141:951–960.[Crossref], [Web of Science ®] , [Google Scholar]). A relationship between the asymptotic Bayes criterion and other criteria, such as orthogonality and aberration, is then developed. A lower bound for the criterion is also obtained, and numerical results show that this lower bound is tight. The established results generalize those of Yue et al. (2011 Yue, R.X., Qin, H., Chatterjee, K. (2011). Optimal U-type design for Bayesian nonparametric multiresponse prediction. J. Stat. Plann. Inference 141:2472–2479.[Crossref], [Web of Science ®] , [Google Scholar]) from symmetrical case to asymmetrical U-type designs.     

Simultaneous closeness among order statistics to population quantiles

We derive expressions for the probability that an individual order statistic is closest to the target parameter among the order statistics from a complete random sample. Results are given for random variables with bounded and complete support. We then apply these general results to location-scale parameter families of distributions with specific applications to estimation of percentiles. In this case, simultaneous-closeness probabilities depend upon the parameters through the value of p in the percentile and the sample size, n. Results are finally illustrated with the estimation of percentiles for normal and exponential distributions.