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We study the estimation of the strength of signals corresponding to the high valued observations in multivariate binary data. These problems can arise in a variety of areas, such as mass spectrometry or function magnetic resonance imaging (fMRI), where the underlying signals could be interpreted as a proxy for biochemical or physiological response to a condition or treatment. More specifically, the problem we consider involves estimating the sum of a collection of binomial probabilities corresponding to large values of the associated binomial random variables. We emphasize the case where the dimension is much greater than the sample size, and most of the probabilities of the events of interest are close to zero. Two estimation approaches are proposed: conditional maximum likelihood and nonparametric empirical Bayes. We use these estimators to construct a test of homogeneity for two groups of high dimensional multivariate binary data. Simulation studies on the size and power of the proposed tests are given, and the tests are demonstrated using mass spectrometry data from a breast cancer study.  相似文献   
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Abstract The purpose of this research was to explore and explain the role housing plays in rural community vitality. Community vitality refers to economic strength and social well‐being. In spring 2002 we collected primary interview data from informants in 134 small rural communities in nine north‐central states and identified related secondary data from the U.S. census. We developed a structural‐equation‐path model, which supported a “housing decision chain” that influenced community vitality. Based on this research, local housing decisions do play an important role in community vitality. Strong local leaders use housing planning to secure funding to produce a change in the quantity of housing, which in turn positively influences community vitality. Housing inventory also mediated the effects of total population and percentage population change on community vitality, indicating that housing supply is a fundamental ingredient in community growth strategies. These findings support the conclusion that a combination of housing plans and strategies orchestrated by skilled, committed leadership strengthens rural communities. Heretofore the ling between housing and community vitality has not been investigated; evidence‐based data has been missing from the debate on viable rural community‐development strategies.  相似文献   
44.
The gendered subjectivities of high achieving school pupils are examined, demonstrating the uneasy relationship between high educational achievement and peer popularity. Drawing on data from a study involving classroom observation and interviews with 71 high-achieving pupils across nine secondary schools in England, the article focuses on the gendered construction of The Boffin. Judith Butler's work, and Hannah Arendt's conception of pariahs and parvenus, are applied to analyse The Boffin as pariah, and as 'queer' in the classroom. The article explores the ways in which this construction is gendered, and the consequences of its application for girls and boys. It is argued that application of this stigmatised term functioned as a powerful deterrent to 'excessive' performances of achievement, for all pupils. But the risks are particularly acute for boys, to whom the 'naming' of Boffin appeared more readily applied, and for whom marginalization as Boffin appears especially perilous (risking particularly pernicious forms of punishment at the hands of other boys).  相似文献   
45.
In England, when a child dies as a result of suspected maltreatment, the Local Safeguarding Children Board is required to establish whether lessons can be learnt about collaborative working to safeguard children. These reviews usually include recommendations for both inter and intra‐agency training. In this paper, the authors argue that it is crucial, when planning and delivering training in this situation, to recognise the emotional impact on the workforce of the death of a child from maltreatment. This is particularly important when the child has died as a result of fabricated and induced illness (FII) by a carer and professionals may have inadvertently contributed to the child's suffering. Drawing on a case example of training following the death of a child from FII, this paper considers the challenges encountered by those responsible for commissioning and providing training. Attention is given to managing logistics, such as time delays between the death of the child and the eventual publication of the serious case review. The particular knowledge and skills required by trainers, not only in relation to the subject matter but also in managing complex group processes, are discussed. The support required by course participants and the trainers themselves is explored. The paper concludes with a checklist for those commissioning and providing training. Copyright © 2009 John Wiley & Sons, Ltd.  相似文献   
46.
ABSTRACT

Writing is a skill that spans many competencies. The Council on Social Work’s Educational Policy and Accreditation Standards promotes a holistic view of competence informed by knowledge, values, skills, and cognitive and affective processes. This teaching note contributes to the scholarship of teaching and learning by describing a professional writing course that uses a holistic pedagogical approach. We provide pragmatic strategies and assignments that can be readily adapted by other faculty and programs.  相似文献   
47.
Postmodernism charges that sociological methods project ways of thinking and being from the past onto the future, and that sociological forms of presentation are rhetorical defenses of ideologies. Postmodernism contends that sociological theory presents reified constructs no more based in reality than are fictional accounts. Kenneth Burke's logology predates and adequately addresses postmodernism's valid charges against sociology. At the same time, logology avoids the idealistic tendencies and ethical pitfalls of radical forms of postmodernist deconstruction, which acknowledge neither pretextual and extratextual worlds nor the ways in which experience is embodied. While not fully articulated, Burke's logology gives primacy to an embodied, social world prior to text (Body-as-World). Sociology can strengthen both its theoretical arsenal and its response to postmodernism by reacknowledging and reclaiming Burke's logology.  相似文献   
48.
Concurrent and longitudinal relations among parental emotional expressivity, children's sympathy and children's prosocial behavior were assessed with correlations and structural equation modeling when the children were 55–97 months old (N = 214; M age = 73 months, SD = 9.59) and eight years later (N = 130; ages 150–195 months old, M = 171 months, SD = 10.01). Parent emotional expressivity (positive and negative) and children's sympathy were stable across time and early parent‐reported sympathy predicted adolescents' sympathy and prosocial behavior. Parents' positive expressivity was positively related to sympathy and prosocial behavior, but in adolescence, this was likely primarily because of consistency over time. Early observed parental negative expressivity was negatively related to adolescents' prosocial behavior. Reported negative expressivity in childhood was negatively related to boys' sympathy in childhood and positively related to girls' sympathy behavior in adolescence. The later relation remained significant when controlling for the stability of parental expressivity and sympathy, suggesting an emerging positive relation between the variables for girls.  相似文献   
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In “Fatherhood, Cohabitation, and Marriage,” Wade F. Horn, Assistant Secretary for Children and Families at the Department of Health and Human Services, summarizes the importance of fathers to child well-being. He explains that “fatherlessness is a significant risk factor for poor developmental outcomes for children.” This connection has led some observers to view cohabitation as a substitute or at least an alternative to marriage. Horn argues, however, that marriage is the best option for children and that cohabitation is a weak family structure compared with marriage. Children in households with married parents do better on almost every measure of child well-being, even after controlling for income.  相似文献   
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