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11.
Bernard Sébastien David Hoffman Clémence Rigaux Franck Pellissier Jérôme Msihid 《Pharmaceutical statistics》2016,15(6):450-458
This article describes how a frequentist model averaging approach can be used for concentration–QT analyses in the context of thorough QTc studies. Based on simulations, we have concluded that starting from three candidate model families (linear, exponential, and Emax) the model averaging approach leads to treatment effect estimates that are quite robust with respect to the control of the type I error in nearly all simulated scenarios; in particular, with the model averaging approach, the type I error appears less sensitive to model misspecification than the widely used linear model. We noticed also few differences in terms of performance between the model averaging approach and the more classical model selection approach, but we believe that, despite both can be recommended in practice, the model averaging approach can be more appealing because of some deficiencies of model selection approach pointed out in the literature. We think that a model averaging or model selection approach should be systematically considered for conducting concentration–QT analyses. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
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Marcel de Toledo Vieira Maria de Fátima Salgueiro Peter W. F. Smith 《Journal of applied statistics》2016,43(7):1310-1321
We investigate the impacts of complex sampling on point and standard error estimates in latent growth curve modelling of survey data. Methodological issues are illustrated with empirical evidence from the analysis of longitudinal data on life satisfaction trajectories using data from the British Household Panel Survey, a national representative survey in Great Britain. A multi-process second-order latent growth curve model with conditional linear growth is used to study variation in the two perceived life satisfaction latent factors considered. The benefits of accounting for the complex survey design are considered, including obtaining unbiased both point and standard error estimates, and therefore correctly specified confidence intervals and statistical tests. We conclude that, even for the rather elaborated longitudinal data models that were considered, estimation procedures are affected by variance-inflating impacts of complex sampling. 相似文献
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Gómez P González MJ Gil F Lupiáñez JL Moreno MF Rico L Romero I 《Evaluation and program planning》2007,30(2):149-160
The establishment of the European Higher Education Area has involved specifying lists of professional competencies that programs are expected to develop, and with this the need for procedures to measure how every course within a higher education program is aligned with the program's competencies. We propose an instrument for characterizing this alignment, a process that we call assessing the relevance of a course. Using information from the course syllabus (objectives, contents and assessment scheme), our instrument produces indicators for characterizing the syllabus in terms of a competence list and for assessing its coherence. Because assessment involves quality, the results obtained can also be used to revise and improve the course syllabus. We illustrate this process with an example of a methods course from a mathematics teacher education program at a Spanish university. 相似文献
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Social Indicators Research - Monitoring progress towards the Sustainable Development Goals by 2030 requires the global community to disaggregate targets along socio-economic lines, but little has... 相似文献
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Šťastná Anna Kocourková Jiřina Šprocha Branislav 《Population research and policy review》2020,39(3):415-437
Population Research and Policy Review - The paper investigates the transition to second births in Czechia and Slovakia in the context of the development of parental leave policies since the... 相似文献
19.
Verónica Verdía Varela Belén Fernández Suárez Renée DePalma 《International migration (Geneva, Switzerland)》2020,58(5):128-143
The ongoing project of citizenship construction in societies receiving international immigration demands a perspective that takes into account the interests, views and needs of all socio-demographic groups, including those of newcomers as potential new citizens. We interviewed representatives of 16 immigrant associations operating in the Spanish autonomous community of Galicia, reviewed immigration policy in 13 Spanish (Galician) municipalities, and interviewed 20 municipal government staff members who put these into practice. With this research, we aim to explore the perspectives of immigrants with respect to their own integration and to examine how these compare with local policies designed to facilitate these processes. By comparing the immigrant representatives' perceptions with local policy discourses and practice, our study reveals how local integration practice is not only inconsistent with its own policy discourse but also fails to consider and include immigrants' own understandings of what integration means and how it can be achieved. 相似文献
20.
Csongrádi Gyöngyi 《Voluntas: International Journal of Voluntary and Nonprofit Organizations》2020,31(3):646-647
VOLUNTAS: International Journal of Voluntary and Nonprofit Organizations - 相似文献