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21.
This article addresses one of the areas of global concern for Southern youth: HIV rates amongst young people from key communities. In the Asia-Pacific region 95% of all new infections occur amongst those under 25. Furthermore, in this region the nature of the epidemic is concentrated, chiefly affecting people from certain sub-groups such as those who inject drugs, sell sex, participate in male-to-male sex and people who are transgender. In this article we discuss an innovative peer-led leadership and advocacy program for youth which uses post-structural theoretical frames and concepts in an effort to steer against the dominant medicalised and individualising storylines which tend to inform approaches to HIV prevention. We draw on examples and data collected from the NewGen Asia Leadership training program to illustrate the ways post-structural concepts can be used to inform program design as well as analysis and critique of the impact of change efforts. Rather than the traditional focus on transmission of knowledge, skills, and attitudes in prevention efforts, we aim to show how the concepts of positioning, platform, and possibility may be mobilised in strategies used to address the challenge of HIV prevention amongst key youth populations.  相似文献   
22.
Cell‐based potency assays play an important role in the characterization of biopharmaceuticals but they can be challenging to develop in part because of greater inherent variability than other analytical methods. Our objective is to select concentrations on a dose–response curve that will enhance assay robustness. We apply the maximin D‐optimal design concept to the four‐parameter logistic (4PL) model and then derive and compute the maximin D‐optimal design for a challenging bioassay using curves representative of assay variation. The selected concentration points from this ‘best worst case’ design adequately fit a variety of 4PL shapes and demonstrate improved robustness. Copyright © 2015 John Wiley & Sons, Ltd.  相似文献   
23.
The truncated gamma distribution has been widely studied, primarily in life-testing and reliability settings. Most work has assumed an upper bound on the support of the random variable, i.e. the space of the distribution is (0,u). We consider a doubly-truncated gamma random variable restricted by both a lower (l) and upper (u) truncation point, both of which are considered known. We provide simple forms for the density, cumulative distribution function (CDF), moment generating function, cumulant generating function, characteristic function, and moments. We extend the results to describe the density, CDF, and moments of a doubly-truncated noncentral chi-square variable.  相似文献   
24.
This research report highlights selected findings that describe the characteristics of excellent, innovative programs for high‐risk children and adolescents in Massachusetts. The conclusions reported are based on interviews with administrators and providers at nine sites. A research consortium composed of policy makers, administrators, clinicians, and academic researchers recommended the site selections. The study describes a spectrum of innovative practices used to help youngsters in severe crises. Innovative practice was shaped by a common vision of doing treatment within family and community contexts, and coordinating overall care at all levels of the family's social and professional networks. Topics addressed include an examination of the core values directing these programs, the four distinct subtypes of design, therapeutic approaches, management, and evaluation. Obstacles to innovation are considered in light of current policy and practice limitations. The discussion concludes with a summary of the challenges and future directions for policy makers, funding agencies, program directors, and clinicians committed to addressing the current crisis in mental health care for children and youth.  相似文献   
25.
Societal definitions of intimate partner violence (IPV) are highly gendered and heteronormative, resulting in dissonance regarding cases of same-sex IPV. This study explored perceptions of IPV when the context of the case is inconsistent with societal norms regarding sex and sexuality. Mock jurors read a vignette describing a case of alleged IPV in which the sex and sexual orientation of the defendant were manipulated. Participants (N = 415) rendered a verdict and provided ratings of the defendant, victim, and case. Results suggest participants were more confident in a guilty verdict when the defendant was male, compared to female. Further, male defendants were perceived as more morally responsible, but only when the victim was female. Perceptions regarding the crime suggest violence perpetrated by a man against a woman is viewed more adversely than any other condition. Data are discussed in terms of implications for legal decision-makers and public policy.  相似文献   
26.
This paper explores how taste and distaste, body image and masculinity play into young people’s perceptions of risk related to steroid use. Data are drawn from a qualitative study on risk-taking among 52 Danish youths enrolled in high school or vocational training. A number of ‘risky’ practices such as drug use, fights, speeding, etc. were discussed. In contrast to these practices, which were primarily described in relation to ‘physical risks’, steroid use was understood as part of an ‘identity’ or ‘lifestyle’ in a way these other risks were not. Few interviewees had used steroids, and the large majority distanced themselves from the practice. Reasons for not wanting to use steroids were related to (1) perceiving the drug to be part of a broader lifestyle and identity that they are not interested in committing to or embodying and (2) finding the body image, physicality and associations with steroid use ‘fake’, ‘gross’ and distasteful. We draw on recent developments in feminist sociological theory related to the gendered body as both a performance and process to understand steroid use as a practice through which the body and self is produced. More than a one-dimensional ‘risky’ practice, we argue that gendered and embodied identities are crucial to understanding the dynamics of steroid use.  相似文献   
27.
This article discusses patterns in mental health of young Australians from age 19 through 25 and explores changes in mental health over these years. Data are derived from five waves of the Australian Life Patterns longitudinal study. The outcome variable in focus was self-reported mental health. Analyses were conducted in two steps using linear mixed models with both fixed and random effects. The analysis shows a negative linear trend in mental health status. The mental health of women was worse than that of men though a negative trend was found in both men and women. Though high socio-economic status (SES) individuals reported best mental health compared to their mid and low-SES peers, a negative trend was identified for them as well as for mid-SES participants. There is weak support for a negative trend among those of low-SES backgrounds. The study adds to evidence that there is a negative trend in mental health in young Australians but that this trend is not uniform across all young people. In light of this we argue the need for further research that analyses patterns of poor mental health in relation to social systems and institutions.  相似文献   
28.
Nine years of experience teaching economics in the Tajikistan and Kyrgyzstan provides knowledge on the nuances and challenges of teaching economics across cultures. Particular categories and difficulties are presented with some examples of how to address them. Conclusions and findings are used to form general guiding principles for teaching economics in the increasingly diverse US classroom. The principles offered in the paper are valuable to English speakers providing economic teaching and training in post-Soviet nations and, more broadly, to anyone teaching economics across cultures. Finally, suggestions based these principles are offered to encourage all professors of economics to carefully consider language, illustrations, diversity of views regarding economics and the multi-cultural nature of university classrooms to better relate to students and be more effective teachers.  相似文献   
29.
New analytic forms for distributions at the heart of internal pilot theory solve many problems inherent to current techniques for linear models with Gaussian errors. Internal pilot designs use a fraction of the data to re-estimate the error variance and modify the final sample size. Too small or too large a sample size caused by an incorrect planning variance can be avoided. However, the usual hypothesis test may need adjustment to control the Type I error rate. A bounding test achieves control of Type I error rate while providing most of the advantages of the unadjusted test. Unfortunately, the presence of both a doubly truncated and an untruncated chi-square random variable complicates the theory and computations. An expression for the density of the sum of the two chi-squares gives a simple form for the test statistic density. Examples illustrate that the new results make the bounding test practical by providing very stable, convergent, and much more accurate computations. Furthermore, the new computational methods are effectively never slower and usually much faster. All results apply to any univariate linear model with fixed predictors and Gaussian errors, with the t-test a special case.  相似文献   
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