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991.
In response surface methodology, one is usually interested in estimating the optimal conditions based on a small number of experimental runs which are designed to optimally sample the experimental space. Typically, regression models are constructed from the experimental data and interrogated in order to provide a point estimate of the independent variable settings predicted to optimize the response. Unfortunately, these point estimates are rarely accompanied with uncertainty intervals. Though classical frequentist confidence intervals can be constructed for unconstrained quadratic models, higher order, constrained or nonlinear models are often encountered in practice. Existing techniques for constructing uncertainty estimates in such situations have not been implemented widely, due in part to the need to set adjustable parameters or because of limited or difficult applicability to constrained or nonlinear problems. To address these limitations a Bayesian method of determining credible intervals for response surface optima was developed. The approach shows good coverage probabilities on two test problems, is straightforward to implement and is readily applicable to the kind of constrained and/or nonlinear problems that frequently appear in practice. 相似文献
992.
Rosa Arboretti Giancristofaro Stefano Bonnini Fortunato Pesarin 《Statistics and Computing》2009,19(2):209-216
In many sciences researchers often meet the problem of establishing if the distribution of a categorical variable is more
concentrated, or less heterogeneous, in population P
1 than in population P
2. An approximate nonparametric solution to this problem is discussed within the permutation context. Such a solution has similarities
to that of testing for stochastic dominance, that is, of testing under order restrictions, for ordered categorical variables.
Main properties of given solution and a Monte Carlo simulation in order to evaluate its degree of approximation and its power
behaviour are examined. Two application examples are also discussed. 相似文献
993.
Julian P. T. Higgins Simon G. Thompson David J. Spiegelhalter 《Journal of the Royal Statistical Society. Series A, (Statistics in Society)》2009,172(1):137-159
Summary. Meta-analysis in the presence of unexplained heterogeneity is frequently undertaken by using a random-effects model, in which the effects underlying different studies are assumed to be drawn from a normal distribution. Here we discuss the justification and interpretation of such models, by addressing in turn the aims of estimation, prediction and hypothesis testing. A particular issue that we consider is the distinction between inference on the mean of the random-effects distribution and inference on the whole distribution. We suggest that random-effects meta-analyses as currently conducted often fail to provide the key results, and we investigate the extent to which distribution-free, classical and Bayesian approaches can provide satisfactory methods. We conclude that the Bayesian approach has the advantage of naturally allowing for full uncertainty, especially for prediction. However, it is not without problems, including computational intensity and sensitivity to a priori judgements. We propose a simple prediction interval for classical meta-analysis and offer extensions to standard practice of Bayesian meta-analysis, making use of an example of studies of 'set shifting' ability in people with eating disorders. 相似文献
994.
In this note we provide a counterexample which resolves conjectures about Hadamard matrices made in this journal. Beder [1998. Conjectures about Hadamard matrices. Journal of Statistical Planning and Inference 72, 7–14] conjectured that if H is a maximal m×n row-Hadamard matrix then m is a multiple of 4; and that if n is a power of 2 then every row-Hadamard matrix can be extended to a Hadamard matrix. Using binary integer programming we obtain a maximal 13×32 row-Hadamard matrix, which disproves both conjectures. Additionally for n being a multiple of 4 up to 64, we tabulate values of m for which we have found a maximal row-Hadamard matrix. Based on the tabulated results we conjecture that a m×n row-Hadamard matrix with m?n-7 can be extended to a Hadamard matrix. 相似文献
995.
Estimation of a relative potency of two preparations in so-called parallel-line assays is presented. A special type of incomplete
Latin square designs where doses of preparations are administered is considered. Testing hypotheses about similarity of preparations
and their relative potency in the case of correlated observations are regarded. Confidence interval for the relative potency
of preparations is also given. Theoretical considerations are applied to point and interval estimation of potencies of new
tuberculins with respect to some international standards tested in experiments on guinea-pigs. 相似文献
996.
Modified inference about the mean of the exponential distribution using moving extreme ranked set sampling 总被引:1,自引:1,他引:0
The maximum likelihood estimator (MLE) and the likelihood ratio test (LRT) will be considered for making inference about the
scale parameter of the exponential distribution in case of moving extreme ranked set sampling (MERSS). The MLE and LRT can
not be written in closed form. Therefore, a modification of the MLE using the technique suggested by Maharota and Nanda (Biometrika
61:601–606, 1974) will be considered and this modified estimator will be used to modify the LRT to get a test in closed form
for testing a simple hypothesis against one sided alternatives. The same idea will be used to modify the most powerful test
(MPT) for testing a simple hypothesis versus a simple hypothesis to get a test in closed form for testing a simple hypothesis
against one sided alternatives. Then it appears that the modified estimator is a good competitor of the MLE and the modified
tests are good competitors of the LRT using MERSS and simple random sampling (SRS). 相似文献
997.
In this paper, we study the MDPDE (minimizing a density power divergence estimator), proposed by Basu et al. (Biometrika 85:549–559,
1998), for mixing distributions whose component densities are members of some known parametric family. As with the ordinary
MDPDE, we also consider a penalized version of the estimator, and show that they are consistent in the sense of weak convergence.
A simulation result is provided to illustrate the robustness. Finally, we apply the penalized method to analyzing the red
blood cell SLC data presented in Roeder (J Am Stat Assoc 89:487–495, 1994).
This research was supported (in part) by KOSEF through Statistical Research Center for Complex Systems at Seoul National University. 相似文献
998.
In this note we consider the equality of the ordinary least squares estimator (OLSE) and the best linear unbiased estimator
(BLUE) of the estimable parametric function in the general Gauss–Markov model. Especially we consider the structures of the
covariance matrix V for which the OLSE equals the BLUE. Our results are based on the properties of a particular reparametrized version of the
original Gauss–Markov model.
相似文献
999.
Randomized response techniques are widely employed in surveys dealing with sensitive questions to ensure interviewee anonymity
and reduce nonrespondents rates and biased responses. Since Warner’s (J Am Stat Assoc 60:63–69, 1965) pioneering work, many
ingenious devices have been suggested to increase respondent’s privacy protection and to better estimate the proportion of
people, π
A
, bearing a sensitive attribute. In spite of the massive use of auxiliary information in the estimation of non-sensitive parameters,
very few attempts have been made to improve randomization strategy performance when auxiliary variables are available. Moving
from Zaizai’s (Model Assist Stat Appl 1:125–130, 2006) recent work, in this paper we provide a class of estimators for π
A
, for a generic randomization scheme, when the mean of a supplementary non-sensitive variable is known. The minimum attainable
variance bound of the class is obtained and the best estimator is also identified. We prove that the best estimator acts as
a regression-type estimator which is at least as efficient as the corresponding estimator evaluated without allowing for the
auxiliary variable. The general results are then applied to Warner and Simmons’ model. 相似文献
1000.
Saralees Nadarajah 《Statistical Papers》2009,50(2):441-443