Insulin-like growth factor 1 receptor polymorphism rs2229765 and circulating interleukin-6 level affect male longevity in a population-based prospective study (Treviso Longeva--TRELONG)

Insulin-like growth factor 1 (IGF-1) signaling modulation has been associated with increased lifespan in model organisms, while high levels of circulating interleukin-6 (IL-6) are a marker of disability and mortality. In the prospective, population-based "Treviso Longeva"--TRELONG Study from Italy (n = 668, age range 70-105.5 years at baseline, followed for seven years) we investigated the effects of survival on the IGF-1 receptor (IGF-1R) gene polymorphism rs2229765, the IL-6 gene promoter polymorphism rs1800795, and plasma concentrations of IGF-1 and IL-6, alone or in combination. We found a sex-dependent effect for the IGF-1R rs2229765 polymorphism, as male carriers of the homozygous A/A genotype survived longer, while the IL-6 rs1800795 genotype did not influence overall or sex-specific longevity. Higher IL-6 levels were more detrimental for survival among males than females, while IGF-1 had no dose-response effect. These findings sustain the hypothesis that sex-specific longevity relies on detectable differences in genetic and biochemical parameters between males and females.     

Choices and life chances: feminism and the politics of generational change

The perception that young women are disengaged from feminist politics has provoked a great deal of tension between feminist generations. Recent feminist research into generational change has largely avoided this tension by focusing on the shifting meanings of feminism and the discrepancy between young women's reluctance to identify as “feminists” and their general acceptance of feminist attitudes toward gender issues. Nevertheless, in an era when gender equity goals seem to be if not slipping backwards then lacking urgency, young women are less likely to identify with a collective feminist politics than are older women. Underpinned by the findings of a major study of the attitudes toward work, family, and retirement of three generations of Australian women, this paper develops an approach that helps explain this reluctance. Drawing on the work of Karl Mannheim, the paper suggests that the cultural currents shaping the consciousness of different generations of women impact significantly on gender identity. The implications of this cultural shift are considered in the context of feminist politics and the contemporary “culture wars.”     

Embedded Diasporas: Shaping the Geopolitical Landscape

This research argues that the capitalistic world-economy, advantageous to the core nations of World Systems Theory, is simultaneously rebalancing inequalities for semi-peripheral nations through a diasporic mechanism that builds reciprocal embeddedness. This is a challenge to world systems theorists' predominant view that the state class structure is fixed. This research adds to international networks research, extending World Systems Theory by building on and integrating the concept of reciprocal embeddedness at the interorganizational and international levels. A diaspora, explicated as one that is organized toward political action, becomes embedded in a core host, uses the host's influence to reduce state class differences, builds a status-equalizing intercultural channel, and induces an agenda for its homeland.     

Pain relief for childbirth: The preferences of pregnant women,midwives and obstetricians

ObjectiveTo compare the personal preferences of pregnant women, midwives and obstetricians regarding a range of physical, psychosocial and pharmacological methods of pain relief for childbirth.MethodSelf-completed questionnaires were posted to a consecutive sample of 400 pregnant women booked-in to a large tertiary referral centre for maternity care in South Australia. A similar questionnaire was distributed to a national sample of 500 obstetricians as well as 425 midwives at: (1) the same hospital as the pregnant women, (2) an outer-metropolitan teaching hospital and (3) a district hospital. Eligible response rates were: pregnant women 31% (n = 123), obstetricians 50% (n = 242) and midwives 49% (n = 210).FindingsOverall, midwives had a greater personal preference for most of the physical pain relief methods and obstetricians a greater personal preference for pharmacological methods than the other groups. Pregnant women's preferences were generally located between the two care provider groups, though somewhat closer to the midwives. All groups had the greatest preference for having a support person for labour with more than 90% of all participants wanting such support. The least preferred method for pregnant women was pethidine/morphine (14%).ConclusionThere are differences in the personal preferences of pregnant women, midwives and obstetricians regarding pain relief for childbirth. It is important that the pain relief methods available in maternity care settings reflect the informed preferences of pregnant women.     

Do religiosity and spirituality really matter for social,mental, and physical health?: A tale of two samples

ABSTRACT

Some prior research has found that religiosity and spirituality can be related to health. However, the relationships are inconsistent, measures of religiosity and spirituality are often problematic and conflated with the health outcomes they are supposed to predict, and very little research on this topic specifies which aspects of health supposedly benefit from religiosity and spirituality. Using two sets of survey data (Sample 1 N = 347; Sample 2 N = 404), we examined whether religiosity and spirituality had direct or indirect effects on physical, mental, and/or social health. We found that spirituality, when conceptualized as belief and experience of the supernatural, had no direct or indirect effect on physical, mental, or social health. Religiosity had a small but significant direct effect on social health in one sample but not the other. We consider our findings in relation to religious privileging in the United States and how proreligious biases can lead to health inequalities.     

Rethinking the ‘race‐class debate’ in South African historiography

This article argues that revisionist historiography has constituted a debate with its liberal opponents which has an ‘either‐or’ form: either class or race has analytic primacy, and either segregation/apartheid is functional or dysfunctional to capitalist growth. This has led revisionists into reductionism and factionalism, despite frequent disclaimers to the contrary. Failure to conceptualise and address the relative independence of social factors has, as a corollary, a functionalist rendition of their relationship to capitalist interests and development. By way of illustration an article by Wolpe and a book by Saul and Gelb are criticised for analytical shortcomings. Finally revised conceptualisations of the relationships between race and class and between capitalist development and racial policies are proposed.     

Professional Development in the Contemporary Educational Context: Encouraging Practice Wisdom

Preparing social work students to be effective practitioners is a complex and challenging task undertaken in a dynamic environment both in terms of the field of social work and the higher education sector. There have been recommendations that self knowledge, empirical knowledge, theoretical knowledge and procedural knowledge are the keys to high standards of social work practice. This paper suggests that the concept of practice wisdom is a useful focus for integrating these different aspects of informed practice and for focusing educational programmes for social work. As practice wisdom is more about process than possessed characteristics then there are important motivational and value-based considerations in developing wise practitioners. This discussion considers motivational and personal narrative aspects of practice wisdom so that it can be integrated into social work teaching.     

Using social media to engage citizens: A study of Italian municipalities

Local public administrations are increasingly interested in involving citizens in public decisions and public life. In this context, social media represent powerful engagement tools. However, social media contribution to establish relationships between citizens and local administrations is largely unexplored. This brief paper has the objective to examine how social media contribute to public engagement by analyzing 119 Italian municipalities.     

The Critical-Ecological Framework: Advancing Knowledge,Practice, and Policy on Older Adult Abuse

The abuse of older adults in our society is a recognized yet understudied issue compared to other forms of family violence. Within this article, research, theory, and practice in family violence and older adult abuse are compared; elements that can be transferred to the field are analyzed; and gaps are identified. An extensive literature review, two focus groups with local stakeholders, and interviews with six key informants recognized as national subject experts formed the basis of this analysis. The results informed the development of a critical-ecological model designed to address the gaps and advance the field.