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181.
Stochastic kinetic models are often used to describe complex biological processes. Typically these models are analytically intractable and have unknown parameters which need to be estimated from observed data. Ideally we would have measurements on all interacting chemical species in the process, observed continuously in time. However, in practice, measurements are taken only at a relatively few time‐points. In some situations, only very limited observation of the process is available, for example settings in which experimenters can only observe noisy observations on the proportion of cells that are alive. This makes the inference task even more problematic. We consider a range of data‐poor scenarios and investigate the performance of various computationally intensive Bayesian algorithms in determining the posterior distribution using data on proportions from a simple birth‐death process.  相似文献   
182.
This mixed-methods study examined how adolescents understand and evaluate different ways to address intergroup harms in schools. In individual interviews, 77 adolescents (M age = 16.49 years; 39 girls, 38 boys) in Bogotá, Colombia, responded to hypothetical vignettes wherein a rival group at school engaged in a transgression against their group. Adolescents reported that students who were harmed should and would talk to school authorities, but also noted they would likely retaliate. In terms of teacher-sanctioned responses to harm, youth endorsed compensation most strongly, followed by apologies, and rated suspension least positively. Youths' explanations for their endorsement of different disciplinary practices reflected varied concerns, including their perceptions of how justice is best achieved and how restoration could be attained.  相似文献   
183.
This study investigated mothers’ and children's constructions of meaning about responsibility for harm in conversations about two experiences when children were hurt by a peer and felt they had either contributed or not contributed to the situation. The sample included 105 Canadian mothers (75% White) and their children (53 girls, 52 boys) across three age groups (M ages = 6.92, 11.14, 15.89 years). Overall, mothers and children emphasized different aspects of responsibility; mothers made more evaluations of acts and discussed the avoidability of harm whereas children referred more to hurtful acts, consequences, reasons, and subsequent responses. Discussions of the child's and peer's responsibility were responsive to the child's perspective on events. The child's responsibility for self-protection was particularly emphasized by mothers and when the child felt they had not contributed to the situation. Children more often mitigated their responsibility as compared to their mothers, and older children referred more to their own and their peer's responsibility for harm. Findings illuminate how conversations with mothers may inform children's judgments of their own and others’ roles in peer conflict.  相似文献   
184.
Group decision making in the presence of multiple conflicting objectives is complex and difficult. This paper describes and evaluates an iterative technique to facilitate multiple objective decision making by multiple decision makers. The proposed method augments an interactive multiobjective optimization procedure with a preference ranking tool and a consensus ranking heuristic. Two multiple objective linear programming (MOLP) solution approaches, the SIMOLP method of Reeves and Franz [39] and the interactive weighted Tchebycheff procedure of Steuer and Choo [49], are recommended optimization strategies to be used independently or in concert. Computational experience suggests that the proposed framework is an effective decision-making tool. The procedure quickly located excellent compromise solutions in a series of test problems with hypothetical decision makers. In addition, human decision makers gave positive evaluations of the procedure and the production plans the procedure provided for a resource allocation case problem.  相似文献   
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186.
The goal of this study was to better understand similarities and differences in preschool children's expression of needs and prosocial responsiveness to peers’ needs across two culturally distinct contexts. Preschoolers were observed in a semi-naturalistic design across rural Mexico and urban Canada, wherein they were instructed to build a tower with blocks. Three- to 6-year-olds (N = 306; 48% female) were divided into 64 peer groups. We coded for children's expression of needs (instrumental, material, or emotional), responses to prosocial opportunities (prosociality, denial, or no response), prosociality without an apparent need (spontaneous prosociality), and types of prosocial behavior (helping, sharing, or comforting). While instrumental and material needs were expressed similarly across both samples, Tzotzil Maya children expressed fewer emotional needs than Canadian children. Failing to respond to others’ needs, followed by denial, were the most frequent need-provoked response in both countries; surprisingly, only 9% of needs received a prosocial response. Though need-provoked prosociality was rare in both cultural contexts, children engaged in considerable spontaneous prosociality which varied as a function of age, gender, and cultural context. Lastly, Canadian more than Tzotzil Maya children denied emotional and instrumental needs (but not material needs). The findings inform how cultural practices may shape the presentation of needs and prosocial responsiveness in peer interactions.  相似文献   
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